Development Level

Tbio 31 | 11,178
Tdark 4 | 6,569

IMPC Phenotype

preweaning lethality, complete... 8 | 979
abnormal craniofacial morpholo... 1 | 33
abnormal embryo size 1 | 220
abnormal forebrain morphology 1 | 10
abnormal heart morphology 1 | 162
abnormal hindbrain morphology 1 | 10
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
decreased circulating alkaline... 1 | 46
decreased lymphocyte cell numb... 1 | 83
decreased vertical activity 1 | 208
edema 1 | 59
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged heart 1 | 210
increased monocyte cell number 1 | 63

Disease

Carcinoma 31 | 11,192
lung cancer 24 | 4,607
group 3 medulloblastoma 22 | 4,002
ovarian cancer 21 | 8,297
osteosarcoma 18 | 7,766
medulloblastoma, large-cell 17 | 6,086
atypical teratoid / rhabdoid tumor 16 | 4,971
glioblastoma 14 | 5,635
primitive neuroectodermal tumor 12 | 2,957
dermatomyositis 11 | 941
psoriasis 11 | 6,514
non-small cell lung cancer 10 | 2,799
Kidney cancer 9 | 2,548
Waldenstrons macroglobulinemia 9 | 742
ependymoma 9 | 4,559
oligodendroglioma 9 | 2,768
Multiple myeloma 8 | 1,296
acute quadriplegic myopathy 8 | 1,133
adult high grade glioma 8 | 3,701
astrocytic glioma 8 | 2,530
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,204
Breast cancer 7 | 3,469
Pick disease 7 | 1,856
colon cancer 6 | 1,428
malignant mesothelioma 6 | 3,135
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,911
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,902
invasive ductal carcinoma 5 | 2,867
lung adenocarcinoma 5 | 2,627
pediatric high grade glioma 5 | 1,035
tuberculosis 5 | 1,963
Astrocytoma, Pilocytic 4 | 3,006
Atopic dermatitis 4 | 915
Cancer 4 | 2,388
HIV Infections 4 | 94
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,872
subependymal giant cell astrocytoma 4 | 2,230
Amyotrophic lateral sclerosis 3 | 437
Leukemia, Myelocytic, Acute 3 | 120
acute myeloid leukemia 3 | 760
adrenocortical carcinoma 3 | 1,385
astrocytoma 3 | 1,113
breast carcinoma 3 | 1,589
nasopharyngeal carcinoma 3 | 1,024
pancreatic cancer 3 | 2,322
Autosomal recessive predisposition 2 | 1,407
Galloway-Mowat syndrome 2 | 15
Influenza 2 | 136
Legionnaires' disease 2 | 20
Leukemia 2 | 103
Leukemia, Acute Myeloid 2 | 17
Leukemia, Myeloid, Acute 2 | 105
NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE 2 | 4
Nephrotic syndrome, idiopathic, steroid-resistant 2 | 4
Rheumatoid arthritis 2 | 1,156
diabetes mellitus 2 | 1,683
ductal carcinoma in situ 2 | 1,686
inflammatory breast cancer 2 | 272
interstitial lung disease 2 | 287
juvenile dermatomyositis 2 | 1,147
sonic hedgehog group medulloblastoma 2 | 459
spina bifida 2 | 1,053
ulcerative colitis 2 | 1,765
ATRIAL FIBRILLATION, FAMILIAL, 1 (disorder) 1 | 21
Acute Promyelocytic Leukemia 1 | 40
Adenocarcinoma of lung 1 | 140
Animal Mammary Neoplasms 1 | 130
Autosomal recessive hypohidrotic ectodermal dysplasia syndrome 1 | 3
Bejel 1 | 5
Brain disease 1 | 95
Degenerative polyarthritis 1 | 110
Deglutition Disorders 1 | 128
DiGeorge syndrome 1 | 46
Disease Models, Animal 1 | 148
Ectodermal Dysplasia 10A, Hypohidrotic/Hair/Nail Type, Autosomal Dominant 1 | 3
Familial atrial fibrillation 1 | 23
Gaucher disease type 1 1 | 177
Hypohidrotic ectodermal dysplasia 1 | 14
Infectious mononucleosis 1 | 13
Irritable bowel syndrome 1 | 57
Kidney Neoplasms 1 | 36
Large intestine cancer 1 | 123
Leukemia, Promyelocytic, Acute 1 | 35
Lymphoid leukemia 1 | 156
Lymphopenia 1 | 66
MYELODYSPLASTIC SYNDROME 1 | 53
Mammary Neoplasms, Animal 1 | 130
Mammary Neoplasms, Experimental 1 | 147
Neutropenia 1 | 71
Osteitis Deformans 1 | 11
Osteoarthritis 1 | 179
Paget's disease of bone 1 | 35
Right atrial isomerism 1 | 27
Spinocerebellar ataxia type 1 1 | 16
Velocardiofacial syndrome 1 | 46
Weight Gain 1 | 95
Yaws 1 | 7
adrenocortical adenoma 1 | 127
permanent atrial fibrillation 1 | 42
triple-A syndrome 1 | 17

Tissue

Blood and immune system 34 | 16,909
Cardiovascular System 34 | 15,192
Digestive Tract 34 | 17,369
Endocrine System 34 | 18,159
Female tissues 34 | 17,400
Liver and Pancreas 34 | 16,750
Male tissues 34 | 17,142
Nervous System 34 | 16,725
Respiratory system 34 | 16,393
Skin and soft tissues 34 | 17,230
Urinary Tract 34 | 16,678

Target Family

Non-IDG 30 | 12,091
Enzyme 5 | 4,145

Reactome Pathway

Interactions of Rev with host ... 35 | 35
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear pore complex protein Nup93 NUP93 Tbio Non-IDG -1.35565 22.2 62
Nuclear envelope pore membrane protein POM 121 POM121 Tbio Non-IDG -1.63036 38.7 49
Nuclear pore complex protein Nup107 NUP107 Tbio Non-IDG -1.49021 31.5 165
Nuclear pore complex protein Nup85 NUP85 Tbio Non-IDG -1.23703 17.9 139
Nucleoporin NDC1 NDC1 Tbio Non-IDG -0.66901 4.57 46
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.26305 200.9 189
Nuclear pore complex protein Nup160 NUP160 Tbio Non-IDG -1.13177 13.6 169
Nucleoprotein TPR TPR Tbio Non-IDG -2.11491 135.6 161
Ran GTPase-activating protein 1 RANGAP1 Tbio Enzyme -1.84078 65.7 254
Nucleoporin-like protein 2 NUPL2 Tbio Non-IDG -1.04073 10.5 78