Development Level

Tbio 32 | 10,625
Tdark 4 | 7,003

IMPC Term

preweaning lethality, complete... 4 | 633

Disease

lung cancer 25 | 4,466
ovarian cancer 21 | 8,484
osteosarcoma 19 | 7,933
medulloblastoma, large-cell 18 | 6,234
group 3 medulloblastoma 16 | 2,254
glioblastoma 14 | 5,572
atypical teratoid / rhabdoid tumor 13 | 4,369
pediatric high grade glioma 12 | 2,712
primitive neuroectodermal tumor 12 | 3,031
Carcinoma 11 | 2,147
dermatomyositis 11 | 933
psoriasis 11 | 6,685
non-small cell lung cancer 10 | 2,798
Waldenstrons macroglobulinemia 9 | 765
oligodendroglioma 9 | 2,849
Multiple myeloma 8 | 1,327
acute quadriplegic myopathy 8 | 1,157
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,289
Breast cancer 7 | 3,094
Pick disease 7 | 1,893
sonic hedgehog group medulloblastoma 7 | 1,482
astrocytic glioma 6 | 2,241
colon cancer 6 | 1,475
malignant mesothelioma 6 | 3,162
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
astrocytoma 5 | 1,493
ependymoma 5 | 2,514
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
invasive ductal carcinoma 5 | 2,950
lung adenocarcinoma 5 | 2,713
Atopic dermatitis 4 | 944
Cancer 4 | 2,346
HIV Infections 4 | 100
atypical teratoid/rhabdoid tumor 4 | 1,095
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
pilocytic astrocytoma 4 | 3,086
subependymal giant cell astrocytoma 4 | 2,287
Leukemia, Myelocytic, Acute 3 | 113
Rheumatoid Arthritis 3 | 1,160
acute myeloid leukemia 3 | 780
adrenocortical carcinoma 3 | 1,427
breast carcinoma 3 | 1,614
nasopharyngeal carcinoma 3 | 1,056
pancreatic cancer 3 | 2,300
posterior fossa group B ependymoma 3 | 1,530
Amyotrophic Lateral Sclerosis 2 | 431
Influenza 2 | 142
Legionnaires' disease 2 | 20
Leukemia 2 | 88
diabetes mellitus 2 | 1,663
ductal carcinoma in situ 2 | 1,745
group 4 medulloblastoma 2 | 1,875
inflammatory breast cancer 2 | 404
interstitial lung disease 2 | 291
juvenile dermatomyositis 2 | 1,189
posterior fossa group A ependymoma 2 | 1,511
spina bifida 2 | 1,064
triple-A syndrome 2 | 18
tuberculosis 2 | 1,557
ulcerative colitis 2 | 2,087
Achalasia 1 | 11
Animal Mammary Neoplasms 1 | 136
Anorexia nervosa 1 | 59
Atherosclerosis 1 | 275
Bejel 1 | 5
Brain disease 1 | 83
Chronic obstructive pulmonary disease 1 | 146
Coronary artery disease 1 | 240
Degenerative polyarthritis 1 | 93
DiGeorge syndrome 1 | 46
Familial atrial fibrillation 1 | 16
Gaucher disease type 1 1 | 171
Hypersensitivity reaction type II disease 1 | 235
Hypertension 1 | 287
IGA Glomerulonephritis 1 | 454
Infectious mononucleosis 1 | 15
Irritable bowel syndrome 1 | 59
Liver Cirrhosis 1 | 101
MYELODYSPLASTIC SYNDROME 1 | 36
Malaria 1 | 140
Mammary Neoplasms, Experimental 1 | 150
Osteitis Deformans 1 | 10
Paget's disease of bone 1 | 28
Peripheral vascular disease 1 | 90
Retinitis pigmentosa 1 | 153
Stomach Neoplasms 1 | 282
Velocardiofacial syndrome 1 | 45
Weight Gain 1 | 87
Yaws 1 | 8
adrenocortical adenoma 1 | 134
adult high grade glioma 1 | 2,148
cystic fibrosis and chronic rhinosinusitis 1 | 213
hepatocellular carcinoma 1 | 532
hereditary spastic paraplegia 1 | 313
medulloblastoma 1 | 1,524
pancreatic carcinoma 1 | 567
permanent atrial fibrillation 1 | 44
progressive supranuclear palsy 1 | 674
tuberculosis and treatment for 3 months 1 | 327
tuberculosis and treatment for 6 months 1 | 686

Tissue

Blood and immune system 36 | 17,995
Cardiovascular System 36 | 17,958
Endocrine System 36 | 18,512
Female tissues 36 | 18,647
Liver and Pancreas 36 | 18,136
Male tissues 36 | 17,969
Nervous System 36 | 18,561
Digestive Tract 35 | 18,473
Respiratory system 35 | 17,484
Skin and soft tissues 35 | 18,115
Urinary Tract 35 | 18,444

Target Family

Non-IDG 31 | 11,971
Enzyme 5 | 4,146

Reactome Pathway

Interactions of Rev with host ... 36 | 36
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nucleoprotein TPR TPR Tbio Non-IDG -2.07876 130.9 158
Nuclear pore complex protein Nup98-Nup96 NUP98 Tbio Enzyme -2.21148 186.3 172
Nucleoporin p58/p45 NUP58 Tdark Non-IDG -0.70757 5.23 31
Nucleoporin-like protein 2 NUPL2 Tbio Non-IDG -0.99049 10.1 66
Ran GTPase-activating protein 1 RANGAP1 Tbio Enzyme -1.81728 64.0 214
GTP-binding nuclear protein Ran RAN Tbio Enzyme -2.52041 303.8 437
Nuclear pore complex protein Nup85 NUP85 Tbio Non-IDG -1.18116 15.9 128
Nuclear pore complex protein Nup160 NUP160 Tbio Non-IDG -1.10072 12.8 160
Nuclear pore glycoprotein p62 NUP62 Tbio Non-IDG -1.74350 57.4 221
Importin subunit beta-1 KPNB1 Tbio Non-IDG -1.50954 31.5 171