Development Level

Tbio 13 | 10,625
Tchem 1 | 1,890
Tclin 1 | 602

IMPC Term

abnormal behavior 1 | 226
abnormal bone structure 1 | 131
abnormal coat appearance 1 | 25
abnormal coping response 1 | 12
abnormal posture 1 | 5
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 49
decreased grip strength 1 | 123
decreased lean body mass 1 | 195
decreased leukocyte cell numbe... 1 | 54
decreased mean corpuscular hem... 1 | 34
decreased total body fat amoun... 1 | 186
decreased vertical activity 1 | 22
hypoactivity 1 | 89
increased circulating HDL chol... 1 | 63
increased circulating LDL chol... 1 | 15
preweaning lethality, incomple... 1 | 260
short tibia 1 | 82

Disease

ovarian cancer 10 | 8,484
medulloblastoma, large-cell 9 | 6,234
osteosarcoma 9 | 7,933
glioblastoma 8 | 5,572
Cancer 7 | 2,346
psoriasis 7 | 6,685
atypical teratoid / rhabdoid tumor 6 | 4,369
oligodendroglioma 6 | 2,849
primitive neuroectodermal tumor 6 | 3,031
lung cancer 5 | 4,466
non-small cell lung cancer 5 | 2,798
Pick disease 4 | 1,893
astrocytoma 4 | 1,493
invasive ductal carcinoma 4 | 2,950
acute myeloid leukemia 3 | 780
astrocytic glioma 3 | 2,241
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
lung carcinoma 3 | 2,844
malignant mesothelioma 3 | 3,162
pancreatic cancer 3 | 2,300
pediatric high grade glioma 3 | 2,712
pilocytic astrocytoma 3 | 3,086
pituitary cancer 3 | 1,972
ulcerative colitis 3 | 2,087
Carcinoma 2 | 2,147
Leukemia, Myelocytic, Acute 2 | 113
Multiple myeloma 2 | 1,327
Myofibrillar myopathy 1 2 | 5
Myofibrillar myopathy 3 2 | 4
Pick's disease 2 | 14
Rheumatoid Arthritis 2 | 1,160
Spinocerebellar ataxia type 2 2 | 19
adult high grade glioma 2 | 2,148
breast carcinoma 2 | 1,614
ependymoma 2 | 2,514
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 832
group 4 medulloblastoma 2 | 1,875
interstitial cystitis 2 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
juvenile dermatomyositis 2 | 1,189
posterior fossa group A ependymoma 2 | 1,511
primary Sjogren syndrome 2 | 789
primary pancreatic ductal adenocarcinoma 2 | 1,271
progressive supranuclear palsy 2 | 674
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 1,557
Adenocarcinoma 1 | 115
Allergic rhinitis 1 | 91
Alzheimer's disease 1 | 644
Anemia 1 | 252
Atopic dermatitis 1 | 944
Autistic Disorder 1 | 320
Barrett's esophagus 1 | 183
Chronic Lymphocytic Leukemia 1 | 242
Colonic Neoplasms 1 | 126
Developmental Disabilities 1 | 20
Enamel caries 1 | 8
Esophageal Neoplasms 1 | 67
Hematologic cancer 1 | 9
Homocystinuria 1 | 23
Huntington's disease 1 | 72
Immune system cancer 1 | 38
Leukemia 1 | 88
Liver carcinoma 1 | 217
Liver disease 1 | 219
Lung Neoplasms 1 | 171
Methylmalonic acidemia 1 | 39
Multiple Sclerosis 1 | 498
Neoplasm Invasiveness 1 | 127
Neoplasm Metastasis 1 | 138
Neoplastic Syndromes, Hereditary 1 | 48
Neuroblastoma 1 | 78
Nonsyndromic deafness 1 | 121
Parkinson Disease 1 | 102
Parkinson's disease 1 | 364
Renal Cell Carcinoma 1 | 199
Squamous cell carcinoma 1 | 94
Stomach Neoplasms 1 | 282
Vasculitis 1 | 64
Vitamin B12 deficiency 1 | 20
Waldenstrons macroglobulinemia 1 | 765
acute quadriplegic myopathy 1 | 1,157
aldosterone-producing adenoma 1 | 664
colon cancer 1 | 1,475
cystic fibrosis 1 | 1,665
dermatomyositis 1 | 933
fibroadenoma 1 | 557
hepatocellular carcinoma 1 | 532
interstitial lung disease 1 | 291
medulloblastoma 1 | 1,524
nephrosclerosis 1 | 329
non-small cell lung carcinoma 1 | 413
ovarian neoplasm 1 | 97
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,795
sonic hedgehog group medulloblastoma 1 | 1,482
spina bifida 1 | 1,064
tuberculosis and treatment for 6 months 1 | 686
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 15 | 17,995
Cardiovascular System 15 | 17,958
Digestive Tract 15 | 18,473
Endocrine System 15 | 18,512
Female tissues 15 | 18,647
Liver and Pancreas 15 | 18,136
Male tissues 15 | 17,969
Nervous System 15 | 18,561
Respiratory system 15 | 17,484
Skin and soft tissues 15 | 18,115
Urinary Tract 15 | 18,444

Target Family

Non-IDG 11 | 11,971
Enzyme 3 | 4,146
Kinase 1 | 634

Reactome Pathway

InlB-mediated entry of Listeri... 15 | 15
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.21113 124.2 150
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG 56.7 150
Growth factor receptor-bound protein 2 GRB2 Tchem Non-IDG -2.99303 933.5 424
Endophilin-A2 SH3GL1 Tbio Non-IDG -1.91832 115.6 229
Endophilin-A1 SH3GL2 Tbio Non-IDG -1.74208 55.9 226
Endophilin-A3 SH3GL3 Tbio Non-IDG -1.01922 9.86 73
Polyubiquitin-C UBC Tbio Non-IDG -2.87012 56.7 130
Polyubiquitin-B UBB Tbio Non-IDG 92.3 370
Epidermal growth factor receptor substrate 15 EPS15 Tbio Non-IDG -2.26621 171.7 162
Signal transducing adapter molecule 1 STAM Tbio Non-IDG -1.06047 12.6 232