Development Level

Tdark 57 | 7,003
Tbio 23 | 10,625
Tchem 3 | 1,890
Tclin 1 | 602

IMPC Term

decreased circulating glucose ... 1 | 121
increased circulating sodium l... 1 | 71
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45

Disease

ulcerative colitis 18 | 2,087
psoriasis 16 | 6,685
lung cancer 15 | 4,466
interstitial cystitis 14 | 2,299
non-small cell lung cancer 14 | 2,798
tuberculosis 14 | 1,557
lung adenocarcinoma 13 | 2,713
osteosarcoma 12 | 7,933
periodontitis 12 | 269
ovarian cancer 11 | 8,484
chronic lymphosyte leukemia 10 | 232
lung carcinoma 10 | 2,844
adrenocortical carcinoma 9 | 1,427
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,988
invasive ductal carcinoma 8 | 2,950
Complement deficiency 7 | 15
pancreatic cancer 7 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,795
primary pancreatic ductal adenocarcinoma 7 | 1,271
subependymal giant cell astrocytoma 7 | 2,287
Duchenne muscular dystrophy 6 | 602
Lupus erythematosus 6 | 80
Multiple myeloma 6 | 1,327
Progressive relapsing multiple sclerosis 6 | 18
Rheumatoid Arthritis 6 | 1,160
acute quadriplegic myopathy 6 | 1,157
colon cancer 6 | 1,475
cutaneous lupus erythematosus 6 | 1,056
glioblastoma 6 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,289
juvenile dermatomyositis 6 | 1,189
limb girdle muscular dystrophy 2A 6 | 156
medulloblastoma, large-cell 6 | 6,234
pilocytic astrocytoma 6 | 3,086
primary Sjogren syndrome 6 | 789
systemic lupus erythematosus 6 | 156
Amebiasis 5 | 22
Becker muscular dystrophy 5 | 187
Kidney disease 5 | 396
Leukemia 5 | 88
Lymphoma 5 | 56
dermatomyositis 5 | 933
diabetes mellitus 5 | 1,663
head and neck cancer and chronic obstructive pulmonary disease 5 | 237
3MC syndrome 4 | 4
Age related macular degeneration 4 | 84
Chronic obstructive pulmonary disease 4 | 146
Immunologic Deficiency Syndromes 4 | 16
Lupus Erythematosus, Systemic 4 | 73
Macular degeneration 4 | 41
Type 1 diabetes mellitus 4 | 101
astrocytoma 4 | 1,493
cystic fibrosis 4 | 1,665
cystic fibrosis and chronic rhinosinusitis 4 | 213
esophageal adenocarcinoma 4 | 737
malignant mesothelioma 4 | 3,162
pediatric high grade glioma 4 | 2,712
posterior fossa group A ependymoma 4 | 1,511
sonic hedgehog group medulloblastoma 4 | 1,482
Breast cancer 3 | 3,094
C1q DEFICIENCY 3 | 3
Carcinoma 3 | 2,147
Down syndrome 3 | 548
IGA Glomerulonephritis 3 | 454
Myositis 3 | 24
Vascular disease 3 | 281
aldosterone-producing adenoma 3 | 664
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 499
chronic kidney disease 3 | 90
gastric carcinoma 3 | 832
group 3 medulloblastoma 3 | 2,254
hemolytic-uremic syndrome 3 | 28
mucosa-associated lymphoid tissue lymphoma 3 | 480
non-small cell lung carcinoma 3 | 413
pituitary cancer 3 | 1,972
Anemia 2 | 252
Atopic dermatitis 2 | 944
Autoimmune Diseases 2 | 33
Cancer 2 | 2,346
Congenital adrenal hyperplasia 2 | 74
Craniofacial Abnormalities 2 | 147
Diabetes Mellitus, Insulin-Dependent 2 | 76
Ehlers-Danlos syndrome 2 | 42
Endometriosis 2 | 535
Inflammation 2 | 109
Malaria 2 | 140
Meningitis 2 | 46
Multiple Sclerosis 2 | 498
Myocardial Ischemia 2 | 169
Osteoporosis 2 | 257
Peripheral Neuropathy 2 | 303
Pigmentation Disorders 2 | 5
Pneumonia 2 | 133
Polycystic Ovary Syndrome 2 | 332
Relapsing fever 2 | 16
Thrombocytopenia 2 | 105
fibroadenoma 2 | 557
nasopharyngeal carcinoma 2 | 1,056
nephrosclerosis 2 | 329

Tissue

Blood and immune system 69 | 17,995
Digestive Tract 69 | 18,473
Female tissues 69 | 18,647
Respiratory system 69 | 17,484
Skin and soft tissues 69 | 18,115
Liver and Pancreas 68 | 18,136
Urinary Tract 68 | 18,444
Cardiovascular System 66 | 17,958
Endocrine System 65 | 18,512
Nervous System 65 | 18,561
Male tissues 62 | 17,969

Target Family

Non-IDG 80 | 11,971
Enzyme 4 | 4,146

Reactome Pathway

Initial triggering of compleme... 84 | 84
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Complement C1q subcomponent subunit C C1QC Tbio Non-IDG -1.27032 17.5 141
Complement C1q subcomponent subunit B C1QB Tbio Non-IDG -1.63026 41.3 161
Complement C1q subcomponent subunit A C1QA Tbio Non-IDG -1.71898 50.3 208
Ig lambda-7 chain C region IGLC7 Tdark Non-IDG 228.7 0
Immunoglobulin lambda variable 1-44 IGLV1-44 Tdark Non-IDG 0.00000 0
Immunoglobulin heavy variable 1-2 IGHV1-2 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 3-15 IGKV3-15 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 2-28 IGKV2-28 Tdark Non-IDG 0.00000 0