Development Level

Tbio 12 | 11,651
Tchem 1 | 1,388

IMPC Phenotype

abnormal spleen morphology 1 | 55
decreased circulating chloride... 1 | 30
decreased vertical activity 1 | 208
preweaning lethality, incomple... 1 | 499

Disease

Carcinoma 12 | 11,493
atypical teratoid / rhabdoid tumor 7 | 5,112
glioblastoma 7 | 5,792
medulloblastoma, large-cell 7 | 6,241
ovarian cancer 7 | 8,520
Breast cancer 6 | 3,578
group 3 medulloblastoma 6 | 4,104
osteosarcoma 6 | 7,950
Kidney cancer 5 | 2,613
adult high grade glioma 5 | 3,801
ependymoma 5 | 4,679
invasive ductal carcinoma 5 | 2,951
psoriasis 5 | 6,694
Acquired metabolic disease 4 | 336
Astrocytoma, Pilocytic 4 | 3,081
Bipolar Disorder 4 | 666
Mental Depression 4 | 333
astrocytic glioma 4 | 2,597
breast carcinoma 4 | 1,638
interstitial cystitis 4 | 2,312
oligodendroglioma 4 | 2,850
primitive neuroectodermal tumor 4 | 3,035
Depressive disorder 3 | 409
Mood Disorders 3 | 184
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
lung carcinoma 3 | 2,843
non-small cell lung cancer 3 | 2,890
ulcerative colitis 3 | 1,819
Alcoholic Intoxication, Chronic 2 | 289
Amnesia 2 | 17
Animal Mammary Neoplasms 2 | 136
Diabetic Angiopathies 2 | 16
Dystonia 2 | 164
Liver cancer 2 | 604
Major Depressive Disorder 2 | 301
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Pick disease 2 | 1,894
Schizophrenia 2 | 1,160
Substance Withdrawal Syndrome 2 | 55
Unipolar Depression 2 | 250
dermatomyositis 2 | 966
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
juvenile dermatomyositis 2 | 1,187
lung adenocarcinoma 2 | 2,716
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
pancreatic cancer 2 | 2,398
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
subependymal giant cell astrocytoma 2 | 2,287
Alcohol dependence 1 | 107
Angle class 2 malocclusion 1 | 57
Angle class 3 malocclusion 1 | 57
Anxiety 1 | 136
Anxiety disease 1 | 113
Atrioventricular block 1 | 35
Bradycardia 1 | 36
Breast Neoplasms 1 | 445
Capuchin ears 1 | 17
Cardiomyopathies 1 | 110
Cervical Dystonia 1 | 26
Common variable immunodeficiency 1 | 101
Cupped ears (finding) 1 | 17
Deafness dystonia syndrome 1 | 21
Dystonia Disorders 1 | 6
Dystonia, Limb 1 | 9
Dystonic Disorders 1 | 7
Fibrosis 1 | 44
Globe disease 1 | 67
Granulomatous amebic encephalitis 1 | 8
Hyperactive behavior 1 | 91
Hyperkinesis 1 | 32
Inadequate arch length for tooth size 1 | 45
Laryngeal dystonia 1 | 5
Leukemia, Myelocytic, Acute 1 | 120
Leukemia, Myeloid, Acute 1 | 105
Malocclusion 1 | 57
Mammary Neoplasms 1 | 425
Meningoencephalitis 1 | 13
Neoplasm Recurrence, Local 1 | 37
Osteoporosis 1 | 363
Polycystic liver disease 1 | 16
Respiratory distress 1 | 43
Round face 1 | 45
Round, full face 1 | 45
Rubinstein-Taybi syndrome 1 | 10
Spasmodic torticollis 1 | 17
Sudden Cardiac Death 1 | 29
Tooth Crowding 1 | 45
Tooth mass arch size discrepancy 1 | 45
Tooth size discrepancy 1 | 45
Torticollis 1 | 18
Ventricular Dysfunction, Left 1 | 22
facioscapulohumeral dystrophy 1 | 288

Tissue

Digestive Tract 13 | 17,369
Endocrine System 13 | 18,159
Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Enzyme 8 | 4,145
Non-IDG 5 | 12,091

Reactome Pathway

Inhibition of adenylate cyclas... 13 | 13
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Guanine nucleotide-binding protein G(i) subunit alpha-1 GNAI1 Tbio Non-IDG -0.63224 3.23 220
Guanine nucleotide-binding protein G(i) subunit alpha-2 GNAI2 Tbio Non-IDG -1.25466 17.2 212
Guanine nucleotide-binding protein G(olf) subunit alpha GNAL Tbio Non-IDG -1.49178 31.9 92
Adenylate cyclase type 2 ADCY2 Tbio Enzyme -1.37166 21.4 117
Adenylate cyclase type 4 ADCY4 Tbio Enzyme -2.04603 107.6 156
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Guanine nucleotide-binding protein G(t) subunit alpha-3 GNAT3 Tbio Non-IDG -2.28370 189.3 111
Adenylate cyclase type 6 ADCY6 Tbio Enzyme -2.05332 113.7 111
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114
Adenylate cyclase type 5 ADCY5 Tchem Enzyme -2.37306 236.5 103