Development Level

Tbio 173 | 11,445
Tdark 81 | 6,588
Tclin 12 | 613
Tchem 6 | 1,598

IMPC Phenotype

increased lean body mass 3 | 172
abnormal QT variability 1 | 10
abnormal pelvic girdle bone mo... 1 | 12
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
aorta dilation 1 | 3
decreased cardiac muscle contr... 1 | 11
decreased circulating calcium ... 1 | 36
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased circulating magnesiu... 1 | 13
decreased lean body mass 1 | 135
decreased lymphocyte cell numb... 1 | 83
decreased mature B cell number 1 | 7
decreased monocyte cell number 1 | 8
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
increased body weight 1 | 25
increased circulating sodium l... 1 | 71
increased grip strength 1 | 41
increased lymphocyte cell numb... 1 | 32
increased mean corpuscular hem... 1 | 36
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
preweaning lethality, complete... 1 | 979
prolonged QRS complex duration 1 | 8
prolonged QT interval 1 | 38
small superior vagus ganglion 1 | 74

Disease

Cancer 116 | 2,499
psoriasis 114 | 6,694
Carcinoma 98 | 11,493
osteosarcoma 79 | 7,950
Ankylosing spondylitis 74 | 140
diabetes mellitus 74 | 1,728
Behcet's disease 72 | 89
Hypersensitivity reaction type II disease 71 | 253
tuberculosis 64 | 2,010
Arthritis 62 | 290
Human immunodeficiency virus infectious disease 61 | 138
Acquired immunodeficiency syndrome 59 | 197
Uveitis 58 | 103
Herpes zoster 57 | 68
Juvenile rheumatoid arthritis 57 | 111
lung cancer 55 | 4,740
interstitial cystitis 53 | 2,312
lung carcinoma 52 | 2,843
Psoriatic arthritis 51 | 86
Stevens-Johnson syndrome 50 | 92
cutaneous lupus erythematosus 50 | 1,057
Rheumatoid arthritis 49 | 1,191
dermatomyositis 47 | 966
Dermatitis 41 | 157
Takayasu's arteritis 38 | 53
glioblastoma 38 | 5,792
Multiple Sclerosis 37 | 540
Synovitis 37 | 78
non-small cell lung cancer 37 | 2,890
ovarian cancer 37 | 8,520
Behcet's syndrome 35 | 50
Congenital adrenal hyperplasia 35 | 73
Nephritis 35 | 51
Retinal vasculitis 35 | 36
Spondyloarthropathy, Susceptibility To, 1 35 | 35
drug-induced hepatitis 35 | 44
ulcerative colitis 34 | 1,819
Kidney disease 31 | 430
Anemia 29 | 365
invasive ductal carcinoma 29 | 2,951
lung adenocarcinoma 29 | 2,716
adult high grade glioma 28 | 3,801
Astrocytoma, Pilocytic 26 | 3,081
Liver disease 26 | 237
Skin disease 26 | 66
primary Sjogren syndrome 26 | 735
Leprosy 24 | 73
medulloblastoma, large-cell 24 | 6,241
Hepatitis B 23 | 108
Primary immunodeficiency disease 23 | 54
Hemochromatosis 22 | 54
Birdshot chorioretinopathy 21 | 23
periodontitis 20 | 293
subependymal giant cell astrocytoma 20 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
atypical teratoid / rhabdoid tumor 18 | 5,112
malignant mesothelioma 17 | 3,232
mucosa-associated lymphoid tissue lymphoma 17 | 484
Autosomal recessive predisposition 16 | 1,442
Pre-Eclampsia 16 | 68
ependymoma 16 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
Human immunodeficiency virus type 1, susceptibility to 15 | 26
Multiple myeloma 15 | 1,332
pancreatic cancer 15 | 2,398
Liver Cirrhosis, Experimental 14 | 769
Psoriasis susceptibility 1 14 | 14
juvenile dermatomyositis 14 | 1,187
head and neck cancer and chronic obstructive pulmonary disease 12 | 239
intraductal papillary-mucinous neoplasm (IPMN) 12 | 3,291
Breast cancer 11 | 3,578
Immunologic Deficiency Syndromes 11 | 113
Schizophrenia 11 | 1,160
breast carcinoma 11 | 1,638
chronic lymphosyte leukemia 11 | 204
Asthma 10 | 385
Duchenne muscular dystrophy 10 | 601
colon cancer 10 | 1,478
ductal carcinoma in situ 10 | 1,745
group 3 medulloblastoma 10 | 4,104
group 4 medulloblastoma 10 | 1,855
pituitary cancer 10 | 1,972
Kidney cancer 9 | 2,613
Lymphoproliferative syndrome 9 | 58
Thrombocytopenia 9 | 197
astrocytic glioma 9 | 2,597
astrocytoma 9 | 1,146
primary pancreatic ductal adenocarcinoma 9 | 1,109
Crohn's disease 8 | 321
Inflammatory bowel disease 8 | 151
Malaria 8 | 160
cystic fibrosis 8 | 1,696
gastric carcinoma 8 | 807
nasopharyngeal carcinoma 8 | 1,058
posterior fossa group A ependymoma 8 | 468
sarcoidosis 8 | 370
Atherosclerosis 7 | 291
Chronic Lymphocytic Leukemia 7 | 262
active Crohn's disease 7 | 922
primitive neuroectodermal tumor 7 | 3,035

Tissue

Blood and immune system 115 | 16,909
Digestive Tract 112 | 17,369
Respiratory system 111 | 16,393
Endocrine System 110 | 18,159
Liver and Pancreas 110 | 16,750
Female tissues 109 | 17,400
Skin and soft tissues 108 | 17,230
Urinary Tract 108 | 16,678
Male tissues 105 | 17,142
Nervous System 101 | 16,725
Cardiovascular System 99 | 15,192

Target Family

Non-IDG 271 | 12,091
Enzyme 1 | 4,145

Reactome Pathway

Immunoregulatory interactions ... 272 | 272
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
HLA class I histocompatibility antigen, B-35 alpha chain HLA-B Tbio Non-IDG -1.88752 1613.5 0
Leukocyte-associated immunoglobulin-like receptor 1 LAIR1 Tbio Non-IDG -1.74760 64.2 487
Natural cytotoxicity triggering receptor 2 NCR2 Tbio Non-IDG -2.05295 100.7 196
CD40 ligand CD40LG Tbio Non-IDG -4.58203 37578.3 1461
Sialic acid-binding Ig-like lectin 11 SIGLEC11 Tbio Non-IDG 0.00000 173
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
T-cell receptor beta chain V region CTL-L17 TCRB Tdark Non-IDG 0.00000 0
Cytotoxic and regulatory T-cell molecule CRTAM Tbio Non-IDG -1.11760 15.6 131
Killer cell immunoglobulin-like receptor 2DL4 KIR2DL4 Tbio Non-IDG -1.87668 75.1 222
Immunoglobulin kappa variable 1D-39 IGKV1D-39 Tdark Non-IDG 0.00000 0