Development Level

Tbio 3 | 11,445

IMPC Phenotype

decreased mean corpuscular vol... 1 | 79

Disease

adult high grade glioma 3 | 3,801
Asthma 2 | 385
Astrocytoma, Pilocytic 2 | 3,081
Cancer 2 | 2,499
Carcinoma 2 | 11,493
Inflammatory bowel disease 2 | 151
Influenza 2 | 142
Melioidosis 2 | 17
Pneumonia 2 | 174
Salmonellosis 2 | 42
astrocytoma 2 | 1,146
glioblastoma 2 | 5,792
lung cancer 2 | 4,740
psoriasis 2 | 6,694
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Allergic hypersensitivity disease 1 | 126
Arthritis 1 | 290
Bronchiolitis 1 | 18
Brucellosis 1 | 24
Cardiovascular system disease 1 | 246
Cell Transformation, Neoplastic 1 | 97
Cholestasis, Extrahepatic 1 | 25
Connective tissue disease 1 | 62
Depressed mood 1 | 17
Diffuse large B-cell lymphoma 1 | 39
Dizziness 1 | 26
Eosinophilia 1 | 28
Gingival Hemorrhage 1 | 18
Hematologic Neoplasms 1 | 22
Hypersensitivity reaction type II disease 1 | 253
Hypertension 1 | 396
Hypertensive disease 1 | 292
Immune system cancer 1 | 140
Immunologic Deficiency Syndromes 1 | 113
Impaired lymphocyte transformation with phytohemagglutinin 1 | 1
Inflammation 1 | 120
Keratitis 1 | 62
Kidney disease 1 | 430
Legionnaires' disease 1 | 20
Leukemia 1 | 104
Lupus Erythematosus, Systemic 1 | 67
Lupus erythematosus 1 | 57
Lymphoid leukemia 1 | 160
Lymphoma 1 | 81
Lymphoma, Follicular 1 | 18
Lymphoma, Large B-Cell, Diffuse 1 | 34
MYD88 Deficiency 1 | 1
Macroglobulinemia 1 | 18
Malaria 1 | 160
Meningitis 1 | 67
Multiple Sclerosis 1 | 540
Neoplasm Invasiveness 1 | 161
Neoplastic Cell Transformation 1 | 89
Neutrophil abnormality 1 | 20
Normocytic anemia 1 | 6
Pallor 1 | 40
Peripheral Neuropathy 1 | 134
Peritonitis 1 | 43
Polyclonal elevation of IgM 1 | 1
Polyneuropathy 1 | 64
Prostatic Neoplasms 1 | 495
Recurrent bacterial skin infections 1 | 8
Reperfusion Injury 1 | 86
Respiratory Insufficiency 1 | 132
Respiratory function loss 1 | 121
Systemic lupus erythematosus 1 | 194
Theileriasis 1 | 13
Thrombophilia 1 | 38
Tularemia 1 | 23
Typhoid fever 1 | 22
Vascular disease 1 | 319
Vertigo 1 | 29
WM1 1 | 1
Waldenstrom Macroglobulinemia 1 | 1
cutaneous lupus erythematosus 1 | 1,057
cystic fibrosis 1 | 1,696
diabetes mellitus 1 | 1,728
group 3 medulloblastoma 1 | 4,104
interstitial cystitis 1 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 1 | 3,291
juvenile dermatomyositis 1 | 1,187
lung carcinoma 1 | 2,843
malignant mesothelioma 1 | 3,232
mucosa-associated lymphoid tissue lymphoma 1 | 484
osteosarcoma 1 | 7,950
ovarian cancer 1 | 8,520
pancreatic cancer 1 | 2,398
pancreatic carcinoma 1 | 562
pituitary cancer 1 | 1,972
primitive neuroectodermal tumor 1 | 3,035
ulcerative colitis 1 | 1,819

Tissue

Blood and immune system 3 | 16,909
Cardiovascular System 3 | 15,192
Digestive Tract 3 | 17,369
Endocrine System 3 | 18,159
Female tissues 3 | 17,400
Liver and Pancreas 3 | 16,750
Male tissues 3 | 17,142
Nervous System 3 | 16,725
Respiratory system 3 | 16,393
Skin and soft tissues 3 | 17,230
Urinary Tract 3 | 16,678

Target Family

Non-IDG 3 | 12,091

Reactome Pathway

IRAK4 deficiency (TLR5) 3 | 3
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myeloid differentiation primary response protein MyD88 MYD88 Tbio Non-IDG -3.26747 1795.4 672
Toll-like receptor 10 TLR10 Tbio Non-IDG -1.80961 63.7 288
Toll-like receptor 5 TLR5 Tbio Non-IDG -2.79280 635.6 691