Development Level

Tbio 12 | 11,445
Tchem 4 | 1,598

IMPC Phenotype

abnormal coat appearance 1 | 31
decreased circulating glucose ... 1 | 126
decreased eosinophil cell numb... 1 | 24
preweaning lethality, incomple... 1 | 499
short tibia 1 | 97

Disease

Carcinoma 13 | 11,493
ovarian cancer 11 | 8,520
Cancer 8 | 2,499
glioblastoma 8 | 5,792
psoriasis 7 | 6,694
atypical teratoid / rhabdoid tumor 6 | 5,112
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung cancer 6 | 4,740
osteosarcoma 6 | 7,950
primitive neuroectodermal tumor 6 | 3,035
Breast cancer 5 | 3,578
Mucopolysaccharidosis 5 | 26
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung adenocarcinoma 5 | 2,716
malignant mesothelioma 5 | 3,232
non-small cell lung cancer 5 | 2,890
Autosomal recessive predisposition 4 | 1,442
Neurodegenerative disease 4 | 414
breast carcinoma 4 | 1,638
colon cancer 4 | 1,478
ductal carcinoma in situ 4 | 1,745
ependymoma 4 | 4,679
invasive ductal carcinoma 4 | 2,951
medulloblastoma, large-cell 4 | 6,241
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
pituitary cancer 4 | 1,972
tuberculosis 4 | 2,010
Atopic dermatitis 3 | 952
Duchenne muscular dystrophy 3 | 601
Kidney cancer 3 | 2,613
Multiple myeloma 3 | 1,332
Waldenstrons macroglobulinemia 3 | 765
adrenocortical carcinoma 3 | 1,428
adult high grade glioma 3 | 3,801
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
esophageal adenocarcinoma 3 | 737
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
juvenile dermatomyositis 3 | 1,187
non diabetic and post-ischemic heart failure 3 | 200
ulcerative colitis 3 | 1,819
Acute kidney injury 2 | 70
Adenoma 2 | 167
Astrocytoma, Pilocytic 2 | 3,081
Attention deficit hyperactivity disorder 2 | 278
Big calvaria 2 | 147
Blind Vision 2 | 111
Blindness, Legal 2 | 110
Cherry red spot of the macula 2 | 7
Coarse facial features 2 | 108
Dermatologic disorders 2 | 93
Dysarthria 2 | 192
Gangliosidosis 2 | 20
Increased head circumference 2 | 147
Increased size of cranium 2 | 147
Increased size of skull 2 | 147
Intellectual disability 2 | 1,016
Lymphedema 2 | 42
Muscle hypotonia 2 | 571
Nerve Degeneration 2 | 121
Osteoarthritis 2 | 184
Short stature 2 | 531
Skin atrophy 2 | 16
Skin cancer 2 | 469
Thickened facial skin with coarse facial features 2 | 108
astrocytic glioma 2 | 2,597
astrocytoma 2 | 1,146
gastric carcinoma 2 | 807
lung carcinoma 2 | 2,843
mucopolysaccharidosis IX 2 | 2
mucosa-associated lymphoid tissue lymphoma 2 | 484
nasopharyngeal carcinoma 2 | 1,058
nephrosclerosis 2 | 333
oligodendroglioma 2 | 2,850
pediatric high grade glioma 2 | 1,064
subependymal giant cell astrocytoma 2 | 2,287
Abdominal pain, episodic 1 | 9
Adenomatous Polyposis Coli 1 | 16
Ataxia, Appendicular 1 | 25
Barrett Esophagus 1 | 16
Cerebellar Dysmetria 1 | 56
Dysdiadochokinesis 1 | 25
Edema 1 | 81
Familial cancer of breast 1 | 12
Hydrops Fetalis 1 | 21
Lyme disease 1 | 26
Metatarsus Varus 1 | 24
Non-immune hydrops fetalis 1 | 11
ODONTOID HYPOPLASIA 1 | 16
Onset of lymphedema around puberty 1 | 21
Pain 1 | 103
Periodontal disease 1 | 40
Skin Abnormalities 1 | 37
Toeing-in 1 | 24
Tularemia 1 | 23
intermittent abdominal pain 1 | 9

Tissue

Blood and immune system 16 | 16,909
Cardiovascular System 16 | 15,192
Digestive Tract 16 | 17,369
Endocrine System 16 | 18,159
Female tissues 16 | 17,400
Liver and Pancreas 16 | 16,750
Male tissues 16 | 17,142
Nervous System 16 | 16,725
Respiratory system 16 | 16,393
Skin and soft tissues 16 | 17,230
Urinary Tract 16 | 16,678

Target Family

Enzyme 9 | 4,145
Non-IDG 6 | 12,091
Transporter 1 | 473

Reactome Pathway

Hyaluronan metabolism 16 | 16
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Cell migration-inducing and hyaluronan-binding protein CEMIP Tbio Non-IDG -1.58210 41.5 144
Calcineurin B homologous protein 1 CHP1 Tbio Non-IDG -1.63966 41.9 162
Sodium/hydrogen exchanger 1 SLC9A1 Tchem Transporter -2.93178 921.2 198
Hyaluronan synthase 1 HAS1 Tbio Enzyme -3.15895 1400.6 126
Hyaluronan synthase 2 HAS2 Tbio Enzyme -2.48728 287.4 109
Stabilin-2 STAB2 Tbio Non-IDG -2.81864 640.7 72
Lymphatic vessel endothelial hyaluronic acid receptor 1 LYVE1 Tbio Non-IDG -2.77184 557.5 586
Hyaluronidase-2 HYAL2 Tbio Enzyme -2.01424 105.1 212
Hyaluronidase-1 HYAL1 Tbio Enzyme -1.88328 77.3 220
Hyaluronidase-3 HYAL3 Tbio Enzyme -0.92743 7.88 126