Development Level

Tbio 5 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613

Collection

GPCR: IDG Consortium (Targets) 1 | 126

IMPC Phenotype

preweaning lethality, complete... 1 | 979

Disease

Cancer 8 | 2,499
Carcinoma 7 | 11,493
group 3 medulloblastoma 7 | 4,104
lung cancer 7 | 4,740
glioblastoma 5 | 5,792
ovarian cancer 5 | 8,520
Breast cancer 4 | 3,578
ependymoma 4 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
lung adenocarcinoma 4 | 2,716
lung carcinoma 4 | 2,843
medulloblastoma, large-cell 4 | 6,241
Multiple myeloma 3 | 1,332
Waldenstrons macroglobulinemia 3 | 765
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
atypical teratoid / rhabdoid tumor 3 | 5,112
breast carcinoma 3 | 1,638
dermatomyositis 3 | 966
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
oligodendroglioma 3 | 2,850
osteosarcoma 3 | 7,950
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primitive neuroectodermal tumor 3 | 3,035
tuberculosis 3 | 2,010
Astrocytoma, Pilocytic 2 | 3,081
Common variable immunodeficiency 2 | 101
Diabetes Mellitus, Experimental 2 | 108
Intestinal Neoplasms 2 | 12
Kidney cancer 2 | 2,613
Liver Cirrhosis, Experimental 2 | 769
Schizophrenia 2 | 1,160
adrenocortical carcinoma 2 | 1,428
astrocytoma 2 | 1,146
colon cancer 2 | 1,478
ductal carcinoma in situ 2 | 1,745
juvenile dermatomyositis 2 | 1,187
psoriasis 2 | 6,694
spina bifida 2 | 1,074
subependymal giant cell astrocytoma 2 | 2,287
Abortion, Spontaneous 1 | 109
Arthralgia 1 | 90
Barrett's esophagus 1 | 182
Brachycephaly 1 | 88
Broad cranium shape 1 | 88
Cholestasis 1 | 155
Chronic otitis media 1 | 52
Colorectal Neoplasms 1 | 243
Decreased antibody level in blood 1 | 35
Down syndrome 1 | 499
Elevated hepatic transaminases 1 | 81
Glomerulonephritis, IGA 1 | 34
Heart disease 1 | 306
Hepatic enzyme increased 1 | 81
Hepatomegaly 1 | 285
Hypertension 1 | 396
Hypogammaglobulinemia 1 | 35
IGA Glomerulonephritis 1 | 50
Immunologic Deficiency Syndromes 1 | 113
Infantile onset 1 | 238
Influenza 1 | 142
Leukemia 1 | 104
Liver Dysfunction 1 | 99
Liver disease 1 | 237
Liver enzymes abnormal 1 | 81
Liver function test increased 1 | 81
Liver function tests abnormal finding 1 | 81
Lymphadenopathy 1 | 62
Lymphoid leukemia 1 | 160
Lymphopenia 1 | 67
Malaria 1 | 160
Necrosis 1 | 53
Neoplasm Invasiveness 1 | 161
Neoplasm Metastasis 1 | 168
Pneumonia 1 | 174
Psychotic Disorders 1 | 151
Purpura 1 | 43
Schizoaffective Disorder 1 | 55
Seizures 1 | 596
Spontaneous abortion 1 | 113
Subclinical abnormal liver function tests 1 | 81
Transaminases increased 1 | 81
Wide skull shape 1 | 88
active ulcerative colitis 1 | 764
adrenocortical adenoma 1 | 131
atypical teratoid/rhabdoid tumor 1 | 357
chronic rhinosinusitis 1 | 512
cystic fibrosis 1 | 1,696
ear infection chronic 1 | 52
fibroadenoma 1 | 559
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
medulloblastoma 1 | 720
nasopharyngeal carcinoma 1 | 1,058
posterior fossa group A ependymoma 1 | 468
progressive supranuclear palsy 1 | 676
pterygium 1 | 76
type II diabetes mellitus and post-ischemic heart failure 1 | 88

Tissue

Blood and immune system 9 | 16,909
Cardiovascular System 9 | 15,192
Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Male tissues 9 | 17,142
Nervous System 9 | 16,725
Respiratory system 9 | 16,393
Skin and soft tissues 9 | 17,230
Urinary Tract 9 | 16,678

Target Family

Non-IDG 5 | 12,091
Kinase 2 | 634
Enzyme 1 | 4,145
GPCR 1 | 408

Reactome Pathway

HuR (ELAVL1) binds and stabili... 9 | 9
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 ENPP2 Tchem Enzyme -2.62921 463.2 377
Nuclear pore complex protein Nup214 NUP214 Tbio Non-IDG -2.25062 166.6 35
Tumor necrosis factor ligand superfamily member 13 TNFSF13 Tbio Non-IDG -1.40980 22.8 527
Retinoic acid-induced protein 3 GPRC5A Tbio GPCR -1.51692 37.7 294
Protein kinase C delta type PRKCD Tclin Kinase -2.18452 141.4 804
ELAV-like protein 1 ELAVL1 Tchem Non-IDG -2.76074 585.8 338
Exportin-1 XPO1 Tbio Non-IDG -3.14385 1273.6 200
Protein SET SET Tbio Non-IDG -2.57590 358.6 255
Protein kinase C alpha type PRKCA Tchem Kinase -2.40732 226.8 822