Development Level

Tbio 128 | 11,445
Tclin 9 | 613
Tchem 7 | 1,598
Tdark 7 | 6,588

IMPC Phenotype

preweaning lethality, complete... 15 | 979
abnormal heart morphology 3 | 162
decreased vertical activity 3 | 208
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
enlarged heart 3 | 210
abnormal embryo size 2 | 220
abnormal skin morphology 2 | 50
hydrometra 2 | 53
increased leukocyte cell numbe... 2 | 47
preweaning lethality, incomple... 2 | 499
small superior vagus ganglion 2 | 74
abnormal behavioral response t... 1 | 66
abnormal bone structure 1 | 187
abnormal cecum morphology 1 | 7
abnormal craniofacial morpholo... 1 | 33
abnormal epididymis morphology 1 | 42
abnormal forebrain morphology 1 | 10
abnormal heart shape 1 | 5
abnormal hindbrain morphology 1 | 10
abnormal kidney morphology 1 | 65
abnormal midbrain morphology 1 | 10
abnormal neural tube closure 1 | 46
abnormal placenta size 1 | 20
abnormal seminal vesicle morph... 1 | 114
absent pinna reflex 1 | 23
decreased T cell number 1 | 15
decreased caudal vertebrae num... 1 | 53
decreased circulating alkaline... 1 | 46
decreased circulating chloride... 1 | 30
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating total pr... 1 | 49
decreased fasted circulating g... 1 | 65
decreased lymphocyte cell numb... 1 | 83
edema 1 | 59
embryonic growth retardation 1 | 106
enlarged cecum 1 | 5
enlarged epididymis 1 | 31
enlarged seminal vesicle 1 | 10
hemorrhage 1 | 23
improved glucose tolerance 1 | 79
increased CD4-positive, alpha ... 1 | 4
increased blood urea nitrogen ... 1 | 48
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating free fat... 1 | 20
increased grip strength 1 | 41
increased heart rate 1 | 23
increased heart weight 1 | 62
increased mean corpuscular hem... 1 | 96
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
prolonged PR interval 1 | 15
prolonged QT interval 1 | 38
prolonged ST segment 1 | 36
shortened RR interval 1 | 17

Disease

Carcinoma 99 | 11,493
ovarian cancer 90 | 8,520
lung cancer 63 | 4,740
osteosarcoma 57 | 7,950
psoriasis 52 | 6,694
Cancer 49 | 2,499
glioblastoma 48 | 5,792
Multiple myeloma 45 | 1,332
medulloblastoma, large-cell 39 | 6,241
diabetes mellitus 37 | 1,728
atypical teratoid / rhabdoid tumor 34 | 5,112
tuberculosis 34 | 2,010
group 3 medulloblastoma 32 | 4,104
Acquired immunodeficiency syndrome 28 | 197
Anemia 26 | 365
Breast cancer 26 | 3,578
Hypersensitivity reaction type II disease 26 | 253
Waldenstrons macroglobulinemia 26 | 765
dermatomyositis 26 | 966
intraductal papillary-mucinous neoplasm (IPMN) 26 | 3,291
adult high grade glioma 25 | 3,801
Kidney disease 24 | 430
non-small cell lung cancer 24 | 2,890
Ankylosing spondylitis 23 | 140
Hepatitis B 23 | 108
Primary immunodeficiency disease 23 | 54
ependymoma 23 | 4,679
malignant mesothelioma 23 | 3,232
Arthritis 22 | 290
Hemochromatosis 22 | 54
Juvenile rheumatoid arthritis 22 | 111
Liver disease 22 | 237
Multiple Sclerosis 22 | 540
Uveitis 22 | 103
Behcet's disease 21 | 89
Birdshot chorioretinopathy 21 | 23
Herpes zoster 21 | 68
Leprosy 21 | 73
Skin disease 21 | 66
invasive ductal carcinoma 21 | 2,951
HIV Infections 20 | 102
subependymal giant cell astrocytoma 20 | 2,287
intraductal papillary-mucinous carcinoma (IPMC) 19 | 2,989
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
oligodendroglioma 18 | 2,850
Astrocytoma, Pilocytic 17 | 3,081
Pick disease 17 | 1,894
intraductal papillary-mucinous adenoma (IPMA) 17 | 2,955
primitive neuroectodermal tumor 17 | 3,035
Kidney cancer 16 | 2,613
acute quadriplegic myopathy 16 | 1,158
astrocytic glioma 16 | 2,597
astrocytoma 16 | 1,146
interstitial cystitis 15 | 2,312
lung carcinoma 15 | 2,843
lung adenocarcinoma 14 | 2,716
ulcerative colitis 14 | 1,819
pancreatic cancer 12 | 2,398
primary Sjogren syndrome 12 | 735
Autosomal recessive predisposition 11 | 1,442
Rheumatoid arthritis 11 | 1,191
colon cancer 11 | 1,478
cutaneous lupus erythematosus 11 | 1,057
juvenile dermatomyositis 11 | 1,187
acute myeloid leukemia 10 | 783
breast carcinoma 10 | 1,638
pediatric high grade glioma 9 | 1,064
Liver Cirrhosis, Experimental 8 | 769
Schizophrenia 8 | 1,160
non primary Sjogren syndrome sicca 8 | 891
Intellectual disability 7 | 1,016
progressive supranuclear palsy 7 | 676
Atopic dermatitis 6 | 952
adrenocortical carcinoma 6 | 1,428
ductal carcinoma in situ 6 | 1,745
group 4 medulloblastoma 6 | 1,855
medulloblastoma 6 | 720
primary pancreatic ductal adenocarcinoma 6 | 1,109
spina bifida 6 | 1,074
Mantle cell lymphoma 5 | 23
Osteoporosis 5 | 363
esophageal adenocarcinoma 5 | 737
hepatocellular carcinoma 5 | 547
sarcoidosis 5 | 370
Alzheimer's disease 4 | 658
Duchenne muscular dystrophy 4 | 601
Dull intelligence 4 | 645
Failure to gain weight 4 | 365
Immunologic Deficiency Syndromes 4 | 113
Leukemia, Myelocytic, Acute 4 | 120
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Pain agnosia 4 | 104
Pediatric failure to thrive 4 | 365
Poor school performance 4 | 645
Stevens-Johnson syndrome 4 | 92
gastric carcinoma 4 | 807
inflammatory breast cancer 4 | 286
sonic hedgehog group medulloblastoma 4 | 467

Tissue

Endocrine System 129 | 18,159
Blood and immune system 128 | 16,909
Digestive Tract 128 | 17,369
Female tissues 128 | 17,400
Nervous System 128 | 16,725
Respiratory system 128 | 16,393
Urinary Tract 128 | 16,678
Liver and Pancreas 127 | 16,750
Male tissues 127 | 17,142
Skin and soft tissues 127 | 17,230
Cardiovascular System 126 | 15,192

Target Family

Non-IDG 90 | 12,091
Enzyme 51 | 4,145
Kinase 5 | 634
Transporter 3 | 473
Epigenetic 1 | 242
Transcription Factor 1 | 1,400

Reactome Pathway

Host Interactions of HIV facto... 151 | 151
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Nuclear pore complex protein Nup160 NUP160 Tbio Non-IDG -1.13177 13.6 169
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
HLA class I histocompatibility antigen, A-80 alpha chain HLA-A Tbio Non-IDG -2.41667 4123.8 0
Proteasome activator complex subunit 4 PSME4 Tdark Non-IDG -1.60128 39.3 43
Nucleoporin NDC1 NDC1 Tbio Non-IDG -0.66901 4.57 46
Proteasome activator complex subunit 2 PSME2 Tbio Non-IDG -1.47440 29.1 305
Proteasome subunit beta type-10 PSMB10 Tchem Enzyme -1.88722 74.3 178
DNA dC->dU-editing enzyme APOBEC-3G APOBEC3G Tbio Non-IDG -2.78510 662.2 477
Ran GTPase-activating protein 1 RANGAP1 Tbio Enzyme -1.84078 65.7 254