Development Level

Tchem 3 | 1,598
Tbio 2 | 11,445

IMPC Phenotype

abnormal gait 1 | 69
decreased circulating bilirubi... 1 | 19
decreased monocyte cell number 1 | 8
enlarged heart 1 | 210
increased blood urea nitrogen ... 1 | 48
increased monocyte cell number 1 | 63
increased or absent threshold ... 1 | 101

Disease

Bilirubin metabolic disorder 3 | 41
Carcinoma 3 | 11,493
Neonatal Jaundice 3 | 30
malignant mesothelioma 3 | 3,232
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
subependymal giant cell astrocytoma 3 | 2,287
Acute kidney injury 2 | 70
Adverse reaction to drug 2 | 61
Anemia 2 | 365
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Cerebral Hemorrhage 2 | 42
Contact Dermatitis 2 | 81
Crigler Najjar syndrome, type 1 2 | 2
Crigler Najjar syndrome, type 2 2 | 2
Dermatitis, Contact 2 | 71
Drug-Related Side Effects and Adverse Reactions 2 | 62
Hypertension 2 | 396
Liver disease 2 | 237
Sickle Cell Anemia 2 | 53
Stomach Neoplasms 2 | 300
adult high grade glioma 2 | 3,801
diabetes mellitus 2 | 1,728
lung cancer 2 | 4,740
lung carcinoma 2 | 2,843
ovarian cancer 2 | 8,520
psoriasis 2 | 6,694
Adrenoleukodystrophy 1 | 29
Age related macular degeneration 1 | 72
Anemia, Hemolytic 1 | 55
Asymptomatic dengue 1 | 5
BILIARY TRACT ABNORMALITY 1 | 16
Biliary Tract Diseases 1 | 16
Blood Coagulation Disorders 1 | 42
Brain disease 1 | 96
Breast Neoplasms 1 | 445
COPD 1 | 118
Carcinoma, Small Cell 1 | 9
Cardiomegaly 1 | 116
Carotid Artery Diseases 1 | 11
Cerebral palsy 1 | 40
Chemical and Drug Induced Liver Injury 1 | 195
Cholelithiasis 1 | 33
Chromosome 2q32-q33 deletion syndrome 1 | 5
Chronic Obstructive Airway Disease 1 | 37
Colitis 1 | 54
Congestive heart failure 1 | 113
Diabetes Mellitus, Experimental 1 | 108
Diabetic Angiopathies 1 | 16
Dihydropyrimidine dehydrogenase deficiency 1 | 6
Encephalopathies 1 | 43
Esophageal Squamous Cell Carcinoma 1 | 77
Fibrosis 1 | 44
Gastroparesis 1 | 22
Glucosephosphate dehydrogenase deficiency 1 | 15
Growth Disorders 1 | 35
Growth delay 1 | 114
Growth failure 1 | 114
Growth retardation 1 | 115
Heart failure 1 | 162
Hematuria 1 | 36
Hepatitis 1 | 67
Hepatorenal syndrome 1 | 6
Hodgkin Disease 1 | 15
Hyperglycemia 1 | 137
Hyperinsulinism 1 | 133
Icterus 1 | 82
Infantile muscular hypotonia 1 | 12
Inflammation 1 | 120
Insulin Resistance 1 | 72
Iron Metabolism Disorders 1 | 5
Ischemia 1 | 28
Kernicterus 1 | 11
Kidney Failure, Chronic 1 | 46
Learning Disorders 1 | 29
Leishmaniasis, Visceral 1 | 13
Liver diseases 1 | 87
Lung Injury 1 | 20
Mammary Neoplasms 1 | 425
Mammary Neoplasms, Experimental 1 | 154
Neurodegenerative Diseases 1 | 38
Neurodegenerative Disorders 1 | 79
Neutropenia 1 | 72
Parkinson Disease 1 | 64
Pneumonia 1 | 174
Poor growth 1 | 114
Pre-Eclampsia 1 | 68
Pulmonary Disease, Chronic Obstructive 1 | 31
Pulmonary Fibrosis 1 | 106
Pulmonary emphysema 1 | 48
Retinal Diseases 1 | 55
Retinal ischemia 1 | 7
SPINOCEREBELLAR ATAXIA 17 1 | 9
Squamous cell carcinoma of esophagus 1 | 77
Thalassemia 1 | 53
Thrombosis 1 | 46
Unconjugated hyperbilirubinemia 1 | 4
Ureteral obstruction 1 | 33
Very poor growth 1 | 114
Wounds and Injuries 1 | 18

Tissue

Digestive Tract 5 | 17,369
Liver and Pancreas 5 | 16,750
Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Enzyme 5 | 4,145

Reactome Pathway

Heme degradation 5 | 5
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Flavin reductase (NADPH) BLVRB Tbio Enzyme -2.31527 194.9 246
UDP-glucuronosyltransferase 1-1 UGT1A1 Tchem Enzyme -2.95436 932.5 146
UDP-glucuronosyltransferase 1-4 UGT1A4 Tbio Enzyme -1.80749 62.9 59
Heme oxygenase 2 HMOX2 Tchem Enzyme -3.00092 967.9 376
Heme oxygenase 1 HMOX1 Tchem Enzyme -3.75004 6181.3 706