Development Level

Tbio 3 | 11,445
Tchem 1 | 1,598

IMPC Phenotype

abnormal heart morphology 1 | 162
cardiovascular system phenotyp... 1 | 36
decreased cardiac muscle contr... 1 | 11
decreased heart rate 1 | 18
decreased total body fat amoun... 1 | 207
decreased vertical activity 1 | 208
embryonic lethality prior to o... 1 | 239
enlarged heart 1 | 210
enlarged spleen 1 | 41
increased circulating choleste... 1 | 66
preweaning lethality, complete... 1 | 979
prolonged PQ interval 1 | 5
prolonged QT interval 1 | 38

Disease

Carcinoma 3 | 11,493
Kidney cancer 3 | 2,613
ovarian cancer 3 | 8,520
Anemia 2 | 365
Atherosclerosis 2 | 291
Coronary artery disease 2 | 268
Kidney disease 2 | 430
Lipid metabolism disorder 2 | 114
Proteinuria 2 | 144
invasive ductal carcinoma 2 | 2,951
oligodendroglioma 2 | 2,850
psoriasis 2 | 6,694
subependymal giant cell astrocytoma 2 | 2,287
3-methylglutaconic aciduria type 1 1 | 7
Abnormality of the liver 1 | 21
Acute Lung Injury 1 | 22
Adenocarcinoma 1 | 122
Adenocarcinoma of lung 1 | 142
Adenocarcinoma of lung (disorder) 1 | 60
Amphetamine-Related Disorders 1 | 74
Amyloidosis 1 | 67
Anemia, Megaloblastic 1 | 16
Animal Mammary Neoplasms 1 | 136
Autistic Disorder 1 | 364
Behcet Syndrome 1 | 21
Behcet's syndrome 1 | 50
Blurred vision 1 | 19
Carcinoma, Hepatocellular 1 | 228
Carcinoma, Renal Cell 1 | 124
Cerebrovascular accident 1 | 63
Cerebrovascular disease 1 | 238
Chemical and Drug Induced Liver Injury 1 | 195
Childhood onset 1 | 38
Cholestasis 1 | 155
Chromosome 2q37 deletion syndrome 1 | 4
Clouding of corneal stroma 1 | 50
Cocaine-Related Disorders 1 | 92
Confusion 1 | 21
Corneal Opacity 1 | 53
Cystinosis 1 | 14
Dementia 1 | 175
Diabetic Cardiomyopathies 1 | 10
Disease of metabolism 1 | 18
Drug Eruptions 1 | 18
Edema 1 | 81
Electromyogram abnormal 1 | 49
Endometrial cancer 1 | 311
Exanthema 1 | 43
Fanconi-like syndrome 1 | 3
Follicular cyst 1 | 1
Generalized amyloid deposition 1 | 6
Glomerulonephritis, Membranous 1 | 7
HIGH DENSITY LIPOPROTEIN CHOLESTEROL LEVEL QUANTITATIVE TRAIT LOCUS 6 1 | 1
HIV Infections 1 | 102
Heart disease 1 | 306
Hematuria 1 | 36
Hemiplegia and hemiparesis 1 | 38
Hemoglobin low 1 | 124
Hepatitis C 1 | 94
High density lipoprotein decreased 1 | 10
Hypertension 1 | 396
Hypesthesia 1 | 7
Hypoalphalipoproteinemias 1 | 10
Hypoxia 1 | 33
Inflammation 1 | 120
Kidney Diseases 1 | 114
Kidney Failure, Chronic 1 | 46
Kidney damage 1 | 25
Liver cancer 1 | 604
Liver carcinoma 1 | 240
Liver disease 1 | 237
Liver diseases 1 | 87
Lung Neoplasms 1 | 232
Lymphadenopathy 1 | 62
Malabsorption of vitamin B12 (cyanocobalamin) 1 | 2
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Marijuana Abuse 1 | 31
Megaloblastic Anemia 1 1 | 2
Megaloblastic anemia 1 | 18
Megaloblastic anemia due to inborn errors of metabolism 1 | 2
Melanoma 1 | 711
Membranous glomerulonephritis 1 | 13
Mesothelioma, Malignant 1 | 105
Neoplastic Processes 1 | 10
Nephrotic Syndrome 1 | 78
Neuropathy 1 | 261
Non-alcoholic Fatty Liver Disease 1 | 42
Paresthesia 1 | 32
Pediatric Obesity 1 | 4
Phencyclidine abuse 1 | 6
Renal Cell Carcinoma 1 | 214
Skin cancer 1 | 469
Stomach Neoplasms 1 | 300
Stroke 1 | 33
Syndromic X-linked intellectual disability Snyder type 1 | 21
Tangier disease 1 | 10
Vitamin B12 deficiency 1 | 20
Vitamin B12 deficiency caused by intestinal malabsorption 1 | 2
Xanthomatosis 1 | 12

Tissue

Blood and immune system 4 | 16,909
Cardiovascular System 4 | 15,192
Digestive Tract 4 | 17,369
Endocrine System 4 | 18,159
Female tissues 4 | 17,400
Liver and Pancreas 4 | 16,750
Male tissues 4 | 17,142
Nervous System 4 | 16,725
Respiratory system 4 | 16,393
Skin and soft tissues 4 | 17,230
Urinary Tract 4 | 16,678

Target Family

Non-IDG 4 | 12,091

Reactome Pathway

HDL clearance 4 | 4
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Vigilin HDLBP Tbio Non-IDG -2.01228 106.9 233
Scavenger receptor class B member 1 SCARB1 Tchem Non-IDG -2.93920 915.7 378
Apolipoprotein A-I APOA1 Tbio Non-IDG -3.62534 3592.8 1151
Cubilin CUBN Tbio Non-IDG -2.18842 161.0 78