Development Level

Tbio 12 | 11,445
Tchem 8 | 1,598
Tclin 3 | 613

IMPC Phenotype

abnormal gait 2 | 69
increased neutrophil cell numb... 2 | 46
preweaning lethality, complete... 2 | 979
abnormal maxilla morphology 1 | 17
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
enlarged lymph nodes 1 | 37
impaired righting response 1 | 26
increased blood urea nitrogen ... 1 | 48
increased lymphocyte cell numb... 1 | 32
increased monocyte cell number 1 | 63
increased spleen weight 1 | 10
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

Carcinoma 19 | 11,493
Cancer 17 | 2,499
osteosarcoma 14 | 7,950
diabetes mellitus 13 | 1,728
lung cancer 13 | 4,740
ovarian cancer 12 | 8,520
psoriasis 12 | 6,694
Obesity 11 | 678
Breast cancer 10 | 3,578
medulloblastoma, large-cell 10 | 6,241
invasive ductal carcinoma 9 | 2,951
pituitary cancer 9 | 1,972
atypical teratoid / rhabdoid tumor 8 | 5,112
malignant mesothelioma 8 | 3,232
Arthritis 7 | 290
Liver Cirrhosis, Experimental 7 | 769
breast carcinoma 7 | 1,638
ductal carcinoma in situ 7 | 1,745
glioblastoma 7 | 5,792
Anemia 6 | 365
Atopic dermatitis 6 | 952
Schizophrenia 6 | 1,160
Short stature 6 | 531
active ulcerative colitis 6 | 764
adult high grade glioma 6 | 3,801
cystic fibrosis 6 | 1,696
group 3 medulloblastoma 6 | 4,104
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
tuberculosis 6 | 2,010
Astrocytoma, Pilocytic 5 | 3,081
Hyperglycemia 5 | 137
Liver Neoplasms, Experimental 5 | 59
Mammary Neoplasms, Experimental 5 | 154
Prostatic Neoplasms 5 | 495
Rheumatoid arthritis 5 | 1,191
Vascular disease 5 | 319
interstitial cystitis 5 | 2,312
lung adenocarcinoma 5 | 2,716
lung carcinoma 5 | 2,843
non-small cell lung cancer 5 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
Acromegaly 4 | 51
Adenoma 4 | 167
Animal Mammary Neoplasms 4 | 136
Asthma 4 | 385
Autistic Disorder 4 | 364
Brain Ischemia 4 | 110
Carcinoma, Hepatocellular 4 | 228
Hyperinsulinism 4 | 133
Hypertension 4 | 396
Hypoglycemia 4 | 152
Hypopituitarism 4 | 40
Hypothyroidism 4 | 122
Insulin Resistance 4 | 72
Liver carcinoma 4 | 240
Mammary Neoplasms, Animal 4 | 136
Multiple Sclerosis 4 | 540
Myocardial Ischemia 4 | 169
Neoplasm Metastasis 4 | 168
Pituitary adenoma 4 | 38
Precancerous Conditions 4 | 80
Stomach Neoplasms 4 | 300
Systemic lupus erythematosus 4 | 194
adrenocortical carcinoma 4 | 1,428
cutaneous lupus erythematosus 4 | 1,057
ependymoma 4 | 4,679
group 4 medulloblastoma 4 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
juvenile dermatomyositis 4 | 1,187
nasopharyngeal carcinoma 4 | 1,058
pancreatic cancer 4 | 2,398
primary Sjogren syndrome 4 | 735
subependymal giant cell astrocytoma 4 | 2,287
ulcerative colitis 4 | 1,819
Acquired metabolic disease 3 | 336
Alzheimer's disease 3 | 658
Cardiomyopathies 3 | 110
Cocaine-Related Disorders 3 | 92
Delayed bone age 3 | 136
Depressive disorder 3 | 409
Dermatitis, Allergic Contact 3 | 67
Diabetes Mellitus, Non-Insulin-Dependent 3 | 145
Diabetes Mellitus, Type 2 3 | 142
Disease Models, Animal 3 | 155
Dwarfism 3 | 37
Fever 3 | 138
Heart disease 3 | 306
Inflammation 3 | 120
Inflammatory bowel disease 3 | 151
Kidney cancer 3 | 2,613
Kidney disease 3 | 430
Lung Neoplasms 3 | 232
Mastocytosis 3 | 27
Polycystic ovary syndrome 3 | 360
Turner syndrome 3 | 28
active Crohn's disease 3 | 922
astrocytoma 3 | 1,146
esophageal adenocarcinoma 3 | 737
medulloblastoma 3 | 720

Tissue

Digestive Tract 23 | 17,369
Endocrine System 23 | 18,159
Female tissues 23 | 17,400
Blood and immune system 22 | 16,909
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Cardiovascular System 20 | 15,192
Urinary Tract 20 | 16,678
Nervous System 19 | 16,725

Target Family

Non-IDG 13 | 12,091
Kinase 4 | 634
Transcription Factor 4 | 1,400
Enzyme 2 | 4,145

Reactome Pathway

Growth hormone receptor signal... 23 | 23
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prolactin PRL Tbio Non-IDG -3.98498 10147.6 1281
Signal transducer and activator of transcription 3 STAT3 Tchem Transcription Factor -3.81500 6459.7 1749
Mitogen-activated protein kinase 3 MAPK3 Tchem Kinase -3.66226 3484.0 1440
Tyrosine-protein kinase JAK2 JAK2 Tclin Kinase -3.54037 3339.7 801
Signal transducer and activator of transcription 1-alpha/beta STAT1 Tchem Transcription Factor -3.33049 2009.0 1596
Growth hormone variant GH2 Tbio Non-IDG -3.15201 1736.7 159
Somatotropin GH1 Tbio Non-IDG -3.03406 1736.7 722
Insulin receptor substrate 1 IRS1 Tbio Non-IDG -3.18611 1482.3 1920
Growth hormone receptor GHR Tclin Non-IDG -3.11970 1322.6 236
Tyrosine-protein phosphatase non-receptor type 1 PTPN1 Tchem Enzyme -3.07650 1308.1 528