Development Level

Tbio 15 | 10,625
Tchem 1 | 1,890

IMPC Term

abnormal vibrissa morphology 1 | 17
decreased body weight 1 | 174
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20

Disease

ovarian cancer 10 | 8,484
glioblastoma 7 | 5,572
osteosarcoma 7 | 7,933
psoriasis 7 | 6,685
astrocytoma 6 | 1,493
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
Glycogen storage disease 5 | 37
Multiple myeloma 5 | 1,327
colon cancer 5 | 1,475
ductal carcinoma in situ 5 | 1,745
medulloblastoma, large-cell 5 | 6,234
Lafora disease 4 | 9
Waldenstrons macroglobulinemia 4 | 765
atypical teratoid / rhabdoid tumor 4 | 4,369
invasive ductal carcinoma 4 | 2,950
lung cancer 4 | 4,466
posterior fossa group A ependymoma 4 | 1,511
Breast cancer 3 | 3,094
Cancer 3 | 2,346
Epilepsy 3 | 346
Myopathy 3 | 128
Neurodegenerative disease 3 | 383
acute myeloid leukemia 3 | 780
breast carcinoma 3 | 1,614
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
Endometrial cancer 2 | 25
Myocardial Ischemia 2 | 169
Myoclonic Epilepsies, Progressive 2 | 12
Myofibrillar myopathy 1 2 | 5
Myofibrillar myopathy 3 2 | 4
Pick's disease 2 | 14
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 557
group 4 medulloblastoma 2 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
malignant mesothelioma 2 | 3,162
oligodendroglioma 2 | 2,849
pancreatic cancer 2 | 2,300
pilocytic astrocytoma 2 | 3,086
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,031
progressive supranuclear palsy 2 | 674
sonic hedgehog group medulloblastoma 2 | 1,482
substance-related disorder 2 | 105
ulcerative colitis 2 | 2,087
Alzheimer's disease 1 | 644
Androgenic alopecia 1 | 10
Apocrine adenoma 1 | 1
Atopic dermatitis 1 | 944
Barre-Lieou syndrome 1 | 2
Bilirubin metabolic disorder 1 | 39
Carcinoma 1 | 2,147
Cardiac Arrhythmia 1 | 20
Cleft Palate, Isolated, And Mental Retardation 1 | 2
Congenital disorder of glycosylation 1 | 53
Dementia 1 | 129
Diabetes Mellitus, Insulin-Dependent 1 | 76
Eastern equine encephalitis 1 | 15
Fascioliasis 1 | 18
Fucosidosis 1 | 10
Galactosemia 1 | 20
Glucosephosphate dehydrogenase deficiency 1 | 15
Glycogen Storage Disease 0, Liver 1 | 1
Glycogen Storage Disease 0, Muscle 1 | 1
Glycogen Storage Disease Type III 1 | 2
Glycogen Storage Disease Type IV 1 | 1
Glycogen Storage Disease XIV 1 | 1
Glycogen storage disease IV 1 | 6
Granular cell tumor 1 | 8
Histiocytosis 1 | 12
Hypoglycemia 1 | 81
IGA Glomerulonephritis 1 | 454
Motor neuritis 1 | 3
Multiple pterygium syndrome 1 | 17
Muscle Weakness 1 | 92
Neurogenic bladder 1 | 16
Neuroleptic malignant syndrome 1 | 8
Neuropathy 1 | 210
Periventricular leukomalacia 1 | 6
Sea-Blue Histiocyte Syndrome 1 | 3
Secondary hyperparathyroidism 1 | 5
Type 1 diabetes mellitus 1 | 101
adult high grade glioma 1 | 2,148
astrocytic glioma 1 | 2,241
atypical teratoid/rhabdoid tumor 1 | 1,095
cystic fibrosis 1 | 1,665
diabetes mellitus 1 | 1,663
gastric carcinoma 1 | 832
hepatocellular carcinoma 1 | 532
lung adenocarcinoma 1 | 2,713
lung carcinoma 1 | 2,844
medulloblastoma 1 | 1,524
non-small cell lung cancer 1 | 2,798
pancreatic carcinoma 1 | 567
pediatric high grade glioma 1 | 2,712
post-traumatic stress disorder 1 | 45
primary pancreatic ductal adenocarcinoma 1 | 1,271
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 1,557

Tissue

Blood and immune system 16 | 17,995
Cardiovascular System 16 | 17,958
Digestive Tract 16 | 18,473
Endocrine System 16 | 18,512
Female tissues 16 | 18,647
Liver and Pancreas 16 | 18,136
Male tissues 16 | 17,969
Nervous System 16 | 18,561
Urinary Tract 16 | 18,444
Respiratory system 15 | 17,484
Skin and soft tissues 15 | 18,115

Target Family

Enzyme 11 | 4,146
Non-IDG 5 | 11,971

Reactome Pathway

Glycogen synthesis 16 | 16
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein phosphatase 1 regulatory subunit 3C PPP1R3C Tbio Enzyme -2.41843 288.0 78
Glycogenin-2 GYG2 Tbio Enzyme -1.91838 86.9 114
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.21113 124.2 150
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG 56.7 150
Glycogen [starch] synthase, muscle GYS1 Tchem Enzyme -2.17524 150.6 211
Polyubiquitin-C UBC Tbio Non-IDG -2.87012 56.7 130
Polyubiquitin-B UBB Tbio Non-IDG 92.3 370
Glycogen [starch] synthase, liver GYS2 Tbio Enzyme -1.54865 34.7 62
Phosphoglucomutase-1 PGM1 Tbio Enzyme -2.67373 478.5 119
1,4-alpha-glucan-branching enzyme GBE1 Tbio Enzyme -2.40980 268.8 190