Development Level

Tbio 14 | 11,651
Tchem 1 | 1,388

IMPC Phenotype

abnormal vibrissa morphology 1 | 25
decreased body weight 1 | 161
decreased circulating glucose ... 1 | 126
decreased circulating glycerol... 1 | 16
increased circulating calcium ... 1 | 34
increased circulating chloride... 1 | 41
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 28
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979

Disease

ovarian cancer 11 | 8,520
Carcinoma 9 | 11,493
glioblastoma 7 | 5,792
osteosarcoma 7 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 7 | 1,962
ductal carcinoma in situ 6 | 1,745
medulloblastoma, large-cell 6 | 6,241
psoriasis 6 | 6,694
Glycogen storage disease 5 | 39
Multiple myeloma 5 | 1,332
astrocytoma 5 | 1,146
atypical teratoid / rhabdoid tumor 5 | 5,112
Autosomal recessive predisposition 4 | 1,442
Waldenstrons macroglobulinemia 4 | 765
colon cancer 4 | 1,478
ependymoma 4 | 4,679
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
lung cancer 4 | 4,740
Astrocytoma, Pilocytic 3 | 3,081
Breast cancer 3 | 3,578
Cancer 3 | 2,499
Epilepsy 3 | 792
Myopathy 3 | 185
acute myeloid leukemia 3 | 783
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
group 3 medulloblastoma 3 | 4,104
oligodendroglioma 3 | 2,850
pancreatic cancer 3 | 2,398
pituitary cancer 3 | 1,972
Anemia 2 | 365
Cardiomyopathies 2 | 110
Lafora disease 2 | 9
Muscle Weakness 2 | 170
Myocardial Ischemia 2 | 169
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Neurogenic Muscular Atrophy 2 | 139
Neurogenic muscle atrophy, especially in the lower limbs 2 | 139
Pick's disease 2 | 15
Seizures 2 | 596
Skeletal muscle atrophy 2 | 139
Slow progression 2 | 89
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 559
gastric cancer 2 | 459
group 4 medulloblastoma 2 | 1,855
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
muscle degeneration 2 | 139
non-small cell lung cancer 2 | 2,890
primitive neuroectodermal tumor 2 | 3,035
progressive supranuclear palsy 2 | 676
substance-related disorder 2 | 162
tuberculosis 2 | 2,010
ulcerative colitis 2 | 1,819
Abnormal upper motor neuron morphology 1 | 11
Abnormality of metabolism/homeostasis 1 | 134
Adult onset 1 | 82
Androgenic alopecia 1 | 9
Arthrogryposis 1 | 54
Ascites 1 | 22
Barre-Lieou syndrome 1 | 2
Cardiac Arrhythmia 1 | 103
Colorectal Neoplasms 1 | 243
Congenital disorder of glycosylation 1 | 54
Cortical white matter abnormalities seen on MRI 1 | 18
Decreased to absent deep tendon reflexes 1 | 42
Distal sensory impairment 1 | 52
Eastern equine encephalitis 1 | 16
Fasting Hypoglycemia 1 | 8
Fucosidosis 1 | 10
Glycogen Storage Disease 0, Liver 1 | 1
Glycogen storage disease IV 1 | 6
Griscelli syndrome type 2 1 | 12
Hyperglycemia, Postprandial 1 | 8
Hypertension, Portal 1 | 22
Increased serum lactate 1 | 60
Ketonemia 1 | 11
Ketosis 1 | 11
Left Ventricular Hypertrophy 1 | 47
Leukoaraiosis 1 | 18
Liver Failure 1 | 73
Multiple pterygium syndrome 1 | 18
Myoclonic Epilepsies, Progressive 1 | 44
Neonatal hypoglycemia 1 | 17
Neurogenic bladder 1 | 16
Paresthesia 1 | 32
Polyhydramnios 1 | 108
Reduced fetal movement 1 | 51
Secondary hyperparathyroidism 1 | 6
Sphincter disturbances 1 | 16
Urinary Incontinence 1 | 50
Ventricular arrhythmia 1 | 27
X-linked cerebral adrenoleukodystrophy 1 | 116
post-traumatic stress disorder 1 | 40

Tissue

Blood and immune system 15 | 16,909
Digestive Tract 15 | 17,369
Endocrine System 15 | 18,159
Female tissues 15 | 17,400
Liver and Pancreas 15 | 16,750
Skin and soft tissues 15 | 17,230
Urinary Tract 15 | 16,678
Cardiovascular System 14 | 15,192
Male tissues 14 | 17,142
Nervous System 14 | 16,725
Respiratory system 14 | 16,393

Target Family

Enzyme 11 | 4,145
Non-IDG 4 | 12,091

Reactome Pathway

Glycogen synthesis 15 | 15
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glycogen [starch] synthase, liver GYS2 Tbio Enzyme -1.61077 38.6 69
Protein phosphatase 1 regulatory subunit 3C PPP1R3C Tbio Enzyme -2.51439 321.6 83
Glycogen [starch] synthase, muscle GYS1 Tchem Enzyme -2.18151 151.1 227
Glycogenin-2 GYG2 Tbio Enzyme -1.96980 92.0 145
1,4-alpha-glucan-branching enzyme GBE1 Tbio Enzyme -2.45230 289.3 230
UTP--glucose-1-phosphate uridylyltransferase UGP2 Tbio Enzyme -2.53652 342.5 148
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427