Development Level

Tbio 15 | 10,625
Tchem 1 | 1,890

IMPC Phenotype

abnormal vibrissa morphology 1 | 17
decreased body weight 1 | 174
decreased circulating glucose ... 1 | 121
decreased circulating glycerol... 1 | 19
increased circulating calcium ... 1 | 32
increased circulating chloride... 1 | 43
increased circulating sodium l... 1 | 71
increased circulating total pr... 1 | 20

Disease

ovarian cancer 10 | 8,491
glioblastoma 7 | 5,572
osteosarcoma 7 | 7,933
psoriasis 7 | 6,685
astrocytoma 6 | 1,493
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,795
Glycogen storage disease 5 | 37
Multiple myeloma 5 | 1,327
colon cancer 5 | 1,475
ductal carcinoma in situ 5 | 1,745
medulloblastoma, large-cell 5 | 6,234
Lafora disease 4 | 9
Waldenstrons macroglobulinemia 4 | 764
atypical teratoid / rhabdoid tumor 4 | 4,369
invasive ductal carcinoma 4 | 2,950
lung cancer 4 | 4,473
posterior fossa group A ependymoma 4 | 1,511
Breast cancer 3 | 3,098
Cancer 3 | 2,346
Epilepsy 3 | 346
Myoclonic Epilepsy of Lafora 3 | 3
Myopathy 3 | 128
Neurodegenerative disease 3 | 383
acute myeloid leukemia 3 | 785
breast carcinoma 3 | 1,614
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
progressive myoclonus epilepsy 3 | 11
Endometrial cancer 2 | 32
Epilepsy, progressive myoclonic 2 2 | 2
Myocardial Ischemia 2 | 169
Myoclonic Epilepsies, Progressive 2 | 12
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Pick's disease 2 | 14
esophageal adenocarcinoma 2 | 737
fibroadenoma 2 | 557
group 4 medulloblastoma 2 | 1,875
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
malignant mesothelioma 2 | 3,163
oligodendroglioma 2 | 2,849
pancreatic cancer 2 | 2,300
pilocytic astrocytoma 2 | 3,086
pituitary cancer 2 | 1,972
primitive neuroectodermal tumor 2 | 3,031
progressive supranuclear palsy 2 | 674
sonic hedgehog group medulloblastoma 2 | 1,482
substance-related disorder 2 | 104
ulcerative colitis 2 | 2,087
Alzheimer's disease 1 | 644
Androgenic alopecia 1 | 10
Apocrine adenoma 1 | 1
Atopic dermatitis 1 | 944
Barre-Lieou syndrome 1 | 2
Bilirubin metabolic disorder 1 | 39
CPI 1 | 1
Carcinoma 1 | 2,147
Cardiac arrhythmia 1 | 26
Cleft Palate, Isolated, And Mental Retardation 1 | 2
Congenital disorder of glycosylation 1 | 53
Congenital disorder of glycosylation 1T 1 | 1
Dementia 1 | 129
Diabetes Mellitus, Insulin-Dependent 1 | 77
Eastern equine encephalitis 1 | 15
Fascioliasis 1 | 18
Fucosidosis 1 | 10
Galactosemia 1 | 20
Glucosephosphate dehydrogenase deficiency 1 | 15
Glycogen Storage Disease 0, Liver 1 | 1
Glycogen Storage Disease 0, Muscle 1 | 1
Glycogen storage disease 0 1 | 1
Glycogen storage disease IV 1 | 6
Granular cell tumor 1 | 8
Histiocytosis 1 | 12
Hypoglycemia 1 | 81
IGA Glomerulonephritis 1 | 454
Motor neuritis 1 | 3
Multiple pterygium syndrome 1 | 17
Muscle Weakness 1 | 92
Muscle glycogen storage disease 0 1 | 1
Neurogenic bladder 1 | 16
Neuroleptic malignant syndrome 1 | 8
Neuropathy 1 | 210
Periventricular leukomalacia 1 | 6
Sea-Blue Histiocyte Syndrome 1 | 3
Secondary hyperparathyroidism 1 | 6
Type 1 diabetes mellitus 1 | 104
adult high grade glioma 1 | 2,148
atypical teratoid/rhabdoid tumor 1 | 1,095
cystic fibrosis 1 | 1,670
hepatocellular carcinoma 1 | 550
lung adenocarcinoma 1 | 2,714
medulloblastoma 1 | 1,524
non-small cell lung cancer 1 | 2,798
pancreatic carcinoma 1 | 567
pediatric high grade glioma 1 | 2,712
post-traumatic stress disorder 1 | 45
primary pancreatic ductal adenocarcinoma 1 | 1,271
subependymal giant cell astrocytoma 1 | 2,287
tuberculosis 1 | 1,563

Tissue

Blood and immune system 16 | 17,994
Cardiovascular System 16 | 17,957
Digestive Tract 16 | 18,472
Endocrine System 16 | 18,511
Female tissues 16 | 18,646
Liver and Pancreas 16 | 18,135
Male tissues 16 | 17,968
Nervous System 16 | 18,560
Urinary Tract 16 | 18,443
Respiratory system 15 | 17,483
Skin and soft tissues 15 | 18,114

Target Family

Enzyme 11 | 4,146
Non-IDG 5 | 11,969

Reactome Pathway

Glycogen synthesis 16 | 16
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phosphoglucomutase-1 PGM1 Tbio Enzyme -2.68147 478.5 119
Laforin, isoform 9 EPM2A Tbio Non-IDG -2.15393 254.1 0
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.10500 124.2 150
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.62947 56.7 150
Glycogen [starch] synthase, muscle GYS1 Tchem Enzyme -2.17279 150.6 211
Glycogenin-2 GYG2 Tbio Enzyme -1.95118 86.9 114
Protein phosphatase 1 regulatory subunit 3C PPP1R3C Tbio Enzyme -2.46104 288.0 78
1,4-alpha-glucan-branching enzyme GBE1 Tbio Enzyme -2.43104 268.8 190
Laforin EPM2A Tbio Enzyme -2.15393 254.1 340
UTP--glucose-1-phosphate uridylyltransferase UGP2 Tbio Enzyme -2.52838 337.9 131