Development Level

Tbio 7 | 10,625
Tchem 6 | 1,890
Tclin 1 | 602

Collection

Eligible Kinase Proteins 3 | 134

IMPC Term

preweaning lethality, incomple... 2 | 260
cataract 1 | 26
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
long tibia 1 | 13

Disease

Glycogen storage disease 11 | 37
osteosarcoma 9 | 7,933
ovarian cancer 7 | 8,492
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
invasive ductal carcinoma 6 | 2,950
malignant mesothelioma 6 | 3,163
ductal carcinoma in situ 5 | 1,745
glioblastoma 5 | 5,572
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,795
psoriasis 5 | 6,685
Myopathy 4 | 128
breast carcinoma 4 | 1,614
group 4 medulloblastoma 4 | 1,875
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
medulloblastoma, large-cell 4 | 6,234
pilocytic astrocytoma 4 | 3,086
Carcinoma 3 | 2,147
Duchenne muscular dystrophy 3 | 602
Myocardial Ischemia 3 | 169
colon cancer 3 | 1,475
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
oligodendroglioma 3 | 2,849
pediatric high grade glioma 3 | 2,712
pituitary cancer 3 | 1,972
posterior fossa group A ependymoma 3 | 1,511
subependymal giant cell astrocytoma 3 | 2,287
tuberculosis 3 | 1,563
Breast cancer 2 | 3,099
Cardiomyopathy 2 | 110
Gastrointestinal stromal tumor 2 | 61
Glycogen Storage Disease IXC 2 | 2
Glycogen Storage Disease, Type IXD 2 | 2
Glycogen storage disease V 2 | 7
Glycogen storage disease VI 2 | 3
Multiple myeloma 2 | 1,328
Myoglobinuria 2 | 11
Pancreatic Neuroendocrine Tumor 2 | 45
Renal Cell Carcinoma 2 | 199
Waldenstrons macroglobulinemia 2 | 765
astrocytoma 2 | 1,493
cystic fibrosis 2 | 1,670
fibroadenoma 2 | 557
group 3 medulloblastoma 2 | 2,254
hereditary spastic paraplegia 2 | 313
lung cancer 2 | 4,473
lung carcinoma 2 | 2,844
sonic hedgehog group medulloblastoma 2 | 1,482
Acute myocardial infarction 1 | 3
Adenoid Cystic Carcinoma 1 | 99
Atopic dermatitis 1 | 944
Cancer 1 | 2,346
Cardiac arrhythmia 1 | 26
Carotid artery dissection 1 | 3
Congenital disorder of glycosylation 1 | 53
Danon disease 1 | 6
Diabetes Mellitus, Insulin-Dependent 1 | 77
Diabetes mellitus type 2 1 | 69
Eastern equine encephalitis 1 | 15
Fabry disease 1 | 9
Fascioliasis 1 | 18
Finger agnosia 1 | 2
Fucosidosis 1 | 10
Gangliosidosis 1 | 17
Gaucher's disease 1 | 25
Glucosephosphate dehydrogenase deficiency 1 | 15
Glucosylceramide beta-glucosidase deficiency 1 | 4
Glycogen Storage Disease Type V 1 | 2
Glycogen storage disease 5 1 | 1
Glycogen storage disease 9C 1 | 1
Glycogen storage disease II 1 | 7
Glycoproteinosis 1 | 13
Gout 1 | 93
Granular cell tumor 1 | 8
Histiocytosis 1 | 12
Hypertrophic Cardiomyopathy 1 | 56
Hypoglycemia 1 | 81
IGA Glomerulonephritis 1 | 454
Inflammatory diarrhea 1 | 2
Intermediate coronary syndrome 1 | 12
Krabbe disease 1 | 11
Left Ventricular Hypertrophy 1 | 24
Leukemia, Lymphocytic, Acute, L1 1 | 11
Liver carcinoma 1 | 217
Lymphoid leukemia 1 | 69
Mucopolysaccharidosis 1 | 24
Multiple Endocrine Neoplasia Type 1 1 | 30
Muscle Weakness 1 | 92
Neuropathy 1 | 210
Parkinson's disease 1 | 364
Ptosis 1 | 42
Respiratory failure 1 | 30
Salivary Gland Neoplasms 1 | 45
Type 1 diabetes mellitus 1 | 104
Ventricular Dysfunction 1 | 7
Vitelliform macular dystrophy 1 | 14
adrenocortical carcinoma 1 | 1,427
atypical teratoid/rhabdoid tumor 1 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
membranous glomerulonephritis 1 | 12
substance-related disorder 1 | 105

Tissue

Blood and immune system 14 | 17,995
Cardiovascular System 14 | 17,958
Digestive Tract 14 | 18,473
Endocrine System 14 | 18,512
Female tissues 14 | 18,647
Liver and Pancreas 14 | 18,136
Male tissues 14 | 17,969
Nervous System 14 | 18,561
Respiratory system 14 | 17,484
Skin and soft tissues 14 | 18,115
Urinary Tract 14 | 18,444

Target Family

Enzyme 9 | 4,146
Kinase 4 | 634
Non-IDG 1 | 11,969

Reactome Pathway

Glycogen breakdown (glycogenol... 14 | 14
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform PHKG2 Tchem Kinase -0.90687 8.65 202
Glycogen phosphorylase, brain form PYGB Tbio Enzyme -1.96736 92.3 345
Glycogenin-2 GYG2 Tbio Enzyme -1.95118 86.9 114
Glycogen phosphorylase, muscle form PYGM Tchem Enzyme -2.23067 154.4 185
Phosphorylase b kinase regulatory subunit beta PHKB Tchem Enzyme -1.11278 11.1 102
Lysosomal alpha-glucosidase GAA Tclin Enzyme -3.05938 1113.9 149
Glycogen debranching enzyme AGL Tbio Non-IDG -2.68773 479.5 115
Phosphorylase b kinase regulatory subunit alpha, liver isoform PHKA2 Tbio Kinase -2.18251 149.4 57
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform PHKA1 Tchem Kinase -1.17088 14.3 67
Phosphoglucomutase-1 PGM1 Tbio Enzyme -2.68147 478.5 119