Development Level

Tbio 7 | 11,445
Tdark 4 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

abnormal lens morphology 1 | 81
cataract 1 | 92
decreased heart rate 1 | 18
decreased red blood cell distr... 1 | 41
increased startle reflex 1 | 112

Disease

Carcinoma 8 | 11,493
ovarian cancer 6 | 8,520
Cancer 5 | 2,499
psoriasis 5 | 6,694
lung cancer 4 | 4,740
non-small cell lung cancer 4 | 2,890
osteosarcoma 4 | 7,950
Autosomal recessive predisposition 3 | 1,442
Bilirubin metabolic disorder 3 | 41
Hypertension 3 | 396
Myocardial Infarction 3 | 151
Schizophrenia 3 | 1,160
group 4 medulloblastoma 3 | 1,855
interstitial cystitis 3 | 2,312
lung adenocarcinoma 3 | 2,716
medulloblastoma, large-cell 3 | 6,241
nasopharyngeal carcinoma 3 | 1,058
pancreatic cancer 3 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
Alcohol dependence 2 | 107
Algoneurodystrophy 2 | 4
Ancylostomiasis 2 | 6
Anemia 2 | 365
Anemia, Hemolytic 2 | 55
Animal Mammary Neoplasms 2 | 136
Atherosclerosis 2 | 291
Breast cancer 2 | 3,578
Cholangitis 2 | 32
Choledocholithiasis 2 | 11
Cholestasis 2 | 155
Congenital hemolytic anemia 2 | 32
Contact Dermatitis 2 | 81
Coronary artery disease 2 | 268
Dermatitis, Contact 2 | 71
Fatty liver disease 2 | 103
Hepatitis B 2 | 108
Hepatitis C 2 | 94
Kidney disease 2 | 430
Liver disease 2 | 237
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Multiple myeloma 2 | 1,332
Obesity 2 | 678
Pancreatitis 2 | 123
Pick disease 2 | 1,894
Progeria 2 | 25
Substance abuse 2 | 59
Toxic encephalopathy 2 | 141
astrocytic glioma 2 | 2,597
atypical teratoid / rhabdoid tumor 2 | 5,112
breast carcinoma 2 | 1,638
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
ependymoma 2 | 4,679
gastric cancer 2 | 459
glioblastoma 2 | 5,792
hepatocellular carcinoma 2 | 547
juvenile dermatomyositis 2 | 1,187
lung carcinoma 2 | 2,843
pancreatic carcinoma 2 | 562
subependymal giant cell astrocytoma 2 | 2,287
tuberculosis 2 | 2,010
Abdominal Pain 1 | 98
Abnormality of metabolism/homeostasis 1 | 134
Alcoholic Intoxication, Chronic 1 | 289
Carcinoma, Non-Small-Cell Lung 1 | 107
Cardiovascular system disease 1 | 246
Cataract 4 multiple types 1 | 14
Chemical and Drug Induced Liver Injury 1 | 195
Diabetic Nephropathies 1 | 37
Diabetic Nephropathy 1 | 34
Diarrhea 1 | 253
Down syndrome 1 | 499
Dysarthria 1 | 192
Epilepsy 1 | 792
Fatty Liver 1 | 70
Gestational diabetes 1 | 26
Hemoglobin low 1 | 124
Liver diseases 1 | 87
Lung Neoplasms 1 | 232
Metabolic acidosis 1 | 90
Mouth Diseases 1 | 12
Myopathy 1 | 185
Neutrophil count decreased 1 | 47
Peripheral Neuropathy 1 | 134
Polyhydramnios 1 | 108
Refractive error 1 | 50
Seizures 1 | 596
Vomiting 1 | 116
Waldenstrons macroglobulinemia 1 | 765
active Crohn's disease 1 | 922
astrocytoma 1 | 1,146
chronic rhinosinusitis 1 | 512
colon cancer 1 | 1,478
cystic fibrosis 1 | 1,696
inflammatory breast cancer 1 | 286
non-small cell lung carcinoma 1 | 317
substance-related disorder 1 | 162
tuberculosis and treatment for 3 months 1 | 179
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Enzyme 12 | 4,145

Reactome Pathway

Glutathione synthesis and recy... 12 | 12
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative glutathione hydrolase 3 proenzyme GGT3P Tdark Enzyme -3.09193 1683.2 0
Glutathione synthetase GSS Tbio Enzyme -2.78139 592.8 229
Gamma-glutamylcyclotransferase GGCT Tbio Enzyme -2.20495 142.5 128
Glutathione hydrolase 6 GGT6 Tdark Enzyme -0.29857 2.02 106
5-oxoprolinase OPLAH Tdark Enzyme 0.00000 39
Cytosolic non-specific dipeptidase CNDP2 Tbio Enzyme -2.43986 262.5 239
Glutathione-specific gamma-glutamylcyclotransferase 2 CHAC2 Tdark Enzyme -0.36798 2.89 93
Glutathione hydrolase 7 GGT7 Tbio Enzyme -0.81907 6.45 101
Glutathione hydrolase 5 proenzyme GGT5 Tbio Enzyme -1.89298 76.6 76
Glutamate--cysteine ligase regulatory subunit GCLM Tbio Enzyme -2.23855 156.3 277