Development Level

Tbio 24 | 11,445
Tchem 7 | 1,598
Tdark 5 | 6,588

IMPC Phenotype

abnormal coat-hair pigmentatio... 1 | 64
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal spleen morphology 1 | 55
abnormal vibrissa morphology 1 | 25
cataract 1 | 92
decreased heart rate 1 | 18
decreased mean corpuscular vol... 1 | 79
decreased red blood cell distr... 1 | 41
enlarged heart 1 | 210
increased heart weight 1 | 62
increased mean corpuscular vol... 1 | 92
increased monocyte cell number 1 | 63
increased startle reflex 1 | 112

Disease

psoriasis 18 | 6,694
ovarian cancer 15 | 8,520
Carcinoma 14 | 11,493
Cancer 13 | 2,499
osteosarcoma 13 | 7,950
glioblastoma 11 | 5,792
Schizophrenia 10 | 1,160
lung carcinoma 10 | 2,843
Breast cancer 9 | 3,578
lung cancer 9 | 4,740
Prostatic Neoplasms 8 | 495
malignant mesothelioma 8 | 3,232
medulloblastoma, large-cell 8 | 6,241
Chemical and Drug Induced Liver Injury 7 | 195
Hypertension 7 | 396
cystic fibrosis 7 | 1,696
group 3 medulloblastoma 7 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
invasive ductal carcinoma 7 | 2,951
non-small cell lung cancer 7 | 2,890
tuberculosis 7 | 2,010
Multiple myeloma 6 | 1,332
Neurodegenerative Diseases 6 | 38
Neurodegenerative Disorders 6 | 79
astrocytic glioma 6 | 2,597
diabetes mellitus 6 | 1,728
ependymoma 6 | 4,679
interstitial cystitis 6 | 2,312
lung adenocarcinoma 6 | 2,716
pancreatic ductal adenocarcinoma liver metastasis 6 | 1,962
subependymal giant cell astrocytoma 6 | 2,287
adrenocortical carcinoma 5 | 1,428
atypical teratoid / rhabdoid tumor 5 | 5,112
colon cancer 5 | 1,478
ductal carcinoma in situ 5 | 1,745
nasopharyngeal carcinoma 5 | 1,058
pancreatic cancer 5 | 2,398
Asthma 4 | 385
Bipolar Disorder 4 | 666
Bladder Neoplasm 4 | 112
Hypertensive disease 4 | 292
Liver Cirrhosis, Experimental 4 | 769
Liver disease 4 | 237
Lung Neoplasms 4 | 232
Myocardial Ischemia 4 | 169
Non-alcoholic Fatty Liver Disease 4 | 42
Urinary Bladder Neoplasms 4 | 114
Xeroderma pigmentosum group D 4 | 33
aldosterone-producing adenoma 4 | 665
group 4 medulloblastoma 4 | 1,855
Amphetamine-Related Disorders 3 | 74
Atherosclerosis 3 | 291
Autosomal recessive predisposition 3 | 1,442
Bilirubin metabolic disorder 3 | 41
Carcinoma, Non-Small-Cell Lung 3 | 107
Carcinoma, Renal Cell 3 | 124
Chromosome Aberrations 3 | 16
Chronic obstructive pulmonary disease 3 | 184
Contact Dermatitis 3 | 81
Dermatitis, Contact 3 | 71
Myocardial Infarction 3 | 151
Osteoarthritis 3 | 184
Parkinson Disease 3 | 64
Pick disease 3 | 1,894
Precancerous Conditions 3 | 80
Psychotic Disorders 3 | 151
Renal Cell Carcinoma 3 | 214
Toxic encephalopathy 3 | 141
Waldenstrons macroglobulinemia 3 | 765
adult high grade glioma 3 | 3,801
breast carcinoma 3 | 1,638
head and neck cancer and chronic obstructive pulmonary disease 3 | 239
non-small cell lung carcinoma 3 | 317
oligodendroglioma 3 | 2,850
pituitary cancer 3 | 1,972
primitive neuroectodermal tumor 3 | 3,035
spina bifida 3 | 1,074
ulcerative colitis 3 | 1,819
Adenoma 2 | 167
Anemia 2 | 365
Atopic dermatitis 2 | 952
Carcinoma, Hepatocellular 2 | 228
Cholestasis 2 | 155
Coronary artery disease 2 | 268
Depressive disorder 2 | 409
Down syndrome 2 | 499
Endometriosis 2 | 540
Hepatitis B 2 | 108
Kidney disease 2 | 430
Leukemia 2 | 104
Liver carcinoma 2 | 240
Male infertility 2 | 206
Mental Depression 2 | 333
Neurodegenerative disease 2 | 414
active Crohn's disease 2 | 922
hepatocellular carcinoma 2 | 547
pancreatic carcinoma 2 | 562
tuberculosis and treatment for 3 months 2 | 179

Tissue

Endocrine System 33 | 18,159
Blood and immune system 32 | 16,909
Digestive Tract 32 | 17,369
Female tissues 32 | 17,400
Male tissues 32 | 17,142
Respiratory system 32 | 16,393
Skin and soft tissues 32 | 17,230
Liver and Pancreas 31 | 16,750
Nervous System 31 | 16,725
Urinary Tract 31 | 16,678
Cardiovascular System 29 | 15,192

Target Family

Enzyme 36 | 4,145

Reactome Pathway

Glutathione conjugation 36 | 36
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Putative glutathione hydrolase 3 proenzyme GGT3P Tdark Enzyme -3.09193 1683.2 0
Glutathione S-transferase theta-2 GSTT2 Tbio Enzyme -1.25193 16.8 0
Glutathione-specific gamma-glutamylcyclotransferase 1 CHAC1 Tbio Enzyme -1.29114 18.9 179
Maleylacetoacetate isomerase GSTZ1 Tbio Enzyme -1.99892 99.5 150
Glutathione S-transferase A5 GSTA5 Tdark Enzyme -0.93224 8.65 46
Glutathione synthetase GSS Tbio Enzyme -2.78139 592.8 229
Gamma-glutamylcyclotransferase GGCT Tbio Enzyme -2.20495 142.5 128
Glutathione hydrolase 6 GGT6 Tdark Enzyme -0.29857 2.02 106
5-oxoprolinase OPLAH Tdark Enzyme 0.00000 39
Microsomal glutathione S-transferase 1 MGST1 Tbio Enzyme -2.30082 197.5 146