Development Level

Tbio 15 | 11,445
Tchem 9 | 1,598
Tclin 4 | 613
Tdark 2 | 6,588

Collection

Ion Channel: IDG Consortium (T... 3 | 99

IMPC Phenotype

decreased body weight 2 | 161
preweaning lethality, complete... 2 | 979
tremors 2 | 39
abnormal behavior 1 | 298
abnormal behavioral response t... 1 | 66
abnormal cecum morphology 1 | 7
abnormal heart morphology 1 | 162
abnormal heart shape 1 | 5
abnormal seminal vesicle morph... 1 | 114
abnormal whole-body plethysmog... 1 | 4
absent pinna reflex 1 | 23
decreased bone mineral content 1 | 151
decreased circulating HDL chol... 1 | 68
decreased circulating LDL chol... 1 | 38
decreased circulating amylase ... 1 | 28
decreased circulating triglyce... 1 | 79
decreased exploration in new e... 1 | 11
decreased grip strength 1 | 116
decreased total body fat amoun... 1 | 207
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged cecum 1 | 5
enlarged heart 1 | 210
enlarged seminal vesicle 1 | 10
hydrometra 1 | 53
hyperactivity 1 | 148
hypoactivity 1 | 132
increased bone mineral content 1 | 108
increased circulating chloride... 1 | 41
increased circulating free fat... 1 | 20
increased circulating sodium l... 1 | 71
increased lean body mass 1 | 172
increased mean corpuscular vol... 1 | 92
increased vertical activity 1 | 24
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Carcinoma 25 | 11,493
glioblastoma 23 | 5,792
atypical teratoid / rhabdoid tumor 20 | 5,112
medulloblastoma, large-cell 20 | 6,241
ependymoma 19 | 4,679
adult high grade glioma 17 | 3,801
primitive neuroectodermal tumor 17 | 3,035
ovarian cancer 16 | 8,520
group 3 medulloblastoma 15 | 4,104
oligodendroglioma 15 | 2,850
osteosarcoma 15 | 7,950
psoriasis 15 | 6,694
Astrocytoma, Pilocytic 14 | 3,081
Pick disease 13 | 1,894
Schizophrenia 13 | 1,160
astrocytic glioma 11 | 2,597
lung carcinoma 11 | 2,843
subependymal giant cell astrocytoma 10 | 2,287
Intellectual disability 8 | 1,016
Kidney cancer 8 | 2,613
Bipolar Disorder 7 | 666
Breast cancer 7 | 3,578
Major Depressive Disorder 7 | 301
lung cancer 7 | 4,740
Epilepsy 6 | 792
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
invasive ductal carcinoma 6 | 2,951
Amyotrophic lateral sclerosis 5 | 451
Depressive disorder 5 | 409
Unipolar Depression 5 | 250
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,989
lung adenocarcinoma 5 | 2,716
malignant mesothelioma 5 | 3,232
tuberculosis 5 | 2,010
Cocaine-Related Disorders 4 | 92
Epilepsy characterized by intractable complex partial seizures 4 | 28
General anesthesia 4 | 53
Lennox-Gastaut syndrome 4 | 34
Liver cancer 4 | 604
Local anesthesia 4 | 40
Mental Depression 4 | 333
Migraine Prevention 4 | 23
Partial seizure 4 | 15
Rheumatoid arthritis 4 | 1,191
Simple partial seizure 4 | 26
Tonic-clonic epilepsy 4 | 47
astrocytoma 4 | 1,146
ductal carcinoma in situ 4 | 1,745
gastric carcinoma 4 | 807
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
spina bifida 4 | 1,074
Alzheimer's disease 3 | 658
Autistic Disorder 3 | 364
Cataract 8 multiple types 3 | 33
Down syndrome 3 | 499
Dull intelligence 3 | 645
Low intelligence 3 | 645
Melanoma 3 | 711
Mental Retardation 3 | 645
Mental deficiency 3 | 645
Polycystic ovary syndrome 3 | 360
Poor school performance 3 | 645
Toxic encephalopathy 3 | 141
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
acute quadriplegic myopathy 3 | 1,158
breast carcinoma 3 | 1,638
colon cancer 3 | 1,478
interstitial cystitis 3 | 2,312
juvenile dermatomyositis 3 | 1,187
pediatric high grade glioma 3 | 1,064
primary Sjogren syndrome 3 | 735
Autosomal recessive predisposition 2 | 1,442
Cancer 2 | 2,499
Cardiomegaly 2 | 116
Enophthalmos 2 | 75
Fragile X syndrome 2 | 34
Heart disease 2 | 306
Hyperactive behavior 2 | 91
Hyperalgesia 2 | 83
Lipoma 2 | 32
Liver Cirrhosis, Experimental 2 | 769
Male infertility 2 | 206
Neurodegenerative disease 2 | 414
Nonorganic psychosis 2 | 84
Parkinson's disease 2 | 392
Psychotic Disorders 2 | 151
Schizoaffective Disorder 2 | 55
Skin cancer 2 | 469
Substance-Related Disorders 2 | 115
Type 2 diabetes mellitus 2 | 272
Vascular disease 2 | 319
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
diabetes mellitus 2 | 1,728
pancreatic carcinoma 2 | 562
progressive supranuclear palsy 2 | 676
severe Alzheimer's disease 2 | 47

Tissue

Endocrine System 29 | 18,159
Nervous System 29 | 16,725
Digestive Tract 28 | 17,369
Blood and immune system 27 | 16,909
Female tissues 27 | 17,400
Male tissues 27 | 17,142
Skin and soft tissues 27 | 17,230
Liver and Pancreas 26 | 16,750
Respiratory system 25 | 16,393
Urinary Tract 25 | 16,678
Cardiovascular System 22 | 15,192

Target Family

Non-IDG 13 | 12,091
Ion Channel 8 | 344
Kinase 7 | 634
Enzyme 2 | 4,145

Reactome Pathway

Glutamate binding, activation ... 30 | 30
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glutamate receptor-interacting protein 1 GRIP1 Tbio Non-IDG -2.18570 152.7 157
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Calcium/calmodulin-dependent protein kinase type II subunit gamma CAMK2G Tchem Kinase -0.94556 7.03 308
Calcium/calmodulin-dependent protein kinase type II subunit beta CAMK2B Tchem Kinase -1.14550 13.6 344
Calcium/calmodulin-dependent protein kinase type II subunit alpha CAMK2A Tchem Kinase -1.82317 50.9 620
Protein kinase C gamma type PRKCG Tchem Kinase -2.04120 103.9 435
Vesicle-fusing ATPase NSF Tbio Enzyme -2.93271 688.8 206
Glutamate receptor-interacting protein 2 GRIP2 Tdark Non-IDG 0.00000 0
Calcium/calmodulin-dependent protein kinase type II subunit delta CAMK2D Tchem Kinase -1.37613 16.9 229
AP-2 complex subunit alpha-1 AP2A1 Tbio Non-IDG -0.60535 3.75 186