Development Level

Tbio 25 | 11,445
Tchem 5 | 1,598
Tdark 4 | 6,588
Tclin 1 | 613

Collection

Kinase: IDG Consortium (Target... 2 | 125

IMPC Phenotype

abnormal bone structure 4 | 187
increased heart weight 4 | 62
increased startle reflex 4 | 112
preweaning lethality, incomple... 2 | 499
decreased circulating chloride... 1 | 30
decreased lean body mass 1 | 135
decreased vertical activity 1 | 208
enlarged heart 1 | 210
enlarged spleen 1 | 41
small kidney 1 | 16
small superior vagus ganglion 1 | 74

Disease

Carcinoma 20 | 11,493
ovarian cancer 19 | 8,520
osteosarcoma 17 | 7,950
glioblastoma 16 | 5,792
medulloblastoma, large-cell 16 | 6,241
ependymoma 14 | 4,679
atypical teratoid / rhabdoid tumor 13 | 5,112
psoriasis 12 | 6,694
Astrocytoma, Pilocytic 11 | 3,081
pancreatic cancer 11 | 2,398
Breast cancer 10 | 3,578
Carney complex 10 | 25
Obesity 10 | 678
adult high grade glioma 10 | 3,801
group 3 medulloblastoma 10 | 4,104
invasive ductal carcinoma 10 | 2,951
lung cancer 10 | 4,740
primitive neuroectodermal tumor 10 | 3,035
Kidney cancer 9 | 2,613
astrocytic glioma 9 | 2,597
lung carcinoma 9 | 2,843
Depressive disorder 8 | 409
Primary pigmented nodular adrenocortical disease 8 | 13
diabetes mellitus 8 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
non-small cell lung cancer 8 | 2,890
pituitary cancer 8 | 1,972
Pick disease 7 | 1,894
interstitial cystitis 7 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 7 | 2,955
oligodendroglioma 7 | 2,850
subependymal giant cell astrocytoma 7 | 2,287
Acromegaly 6 | 51
Adenoma 6 | 167
Cushing's syndrome 6 | 48
Hypertensive disease 6 | 292
Liver cancer 6 | 604
Multiple Endocrine Neoplasia Type 1 6 | 29
active Crohn's disease 6 | 922
group 4 medulloblastoma 6 | 1,855
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
lung adenocarcinoma 6 | 2,716
malignant mesothelioma 6 | 3,232
ulcerative colitis 6 | 1,819
Acrodysostosis 5 | 12
Brachydactyly 5 | 156
Cancer 5 | 2,499
Duchenne muscular dystrophy 5 | 601
Hyperthyroidism 5 | 53
Hypothyroidism 5 | 122
Kidney disease 5 | 430
McCune Albright syndrome 5 | 19
Pituitary adenoma 5 | 38
Pseudohypoparathyroidism 5 | 18
Substance Withdrawal Syndrome 5 | 55
breast carcinoma 5 | 1,638
ductal carcinoma in situ 5 | 1,745
ACTH-secreting pituitary adenoma 4 | 9
Acquired metabolic disease 4 | 336
Adrenal gland cancer 4 | 12
Beckwith-Wiedemann syndrome 4 | 44
Biliary tract cancer 4 | 19
Bipolar Disorder 4 | 666
Bone cancer 4 | 16
Cervix carcinoma 4 | 10
Cushing syndrome due to macronodular adrenal hyperplasia 4 | 5
DOID:3297 4 | 4
Diabetes Mellitus, Non-Insulin-Dependent 4 | 145
Diabetes Mellitus, Type 2 4 | 142
Fibrodysplasia ossificans progressiva 4 | 17
Fibrous dysplasia 4 | 15
Hyperphosphatemia 4 | 32
Hypertension 4 | 396
Hypoparathyroidism 4 | 41
Mccune-Albright Syndrome 4 | 4
Mental Depression 4 | 333
Monostotic fibrous dysplasia 4 | 4
Mood Disorders 4 | 184
Ossifying fibroma 4 | 15
Osteoporosis 4 | 363
Pituitary Adenoma, Growth Hormone-Secreting, 1 4 | 5
Plummer's disease 4 | 11
Polycystic ovary syndrome 4 | 360
Progressive osseous heteroplasia 4 | 4
Pseudohypoparathyroidism type 1C 4 | 4
Pseudohypoparathyroidism, Type 1A 4 | 4
Pseudohypoparathyroidism, Type 1B 4 | 5
Pseudopseudohypoparathyroidism 4 | 6
Small intestine cancer 4 | 12
Stomach cancer 4 | 30
Thyroid cancer 4 | 36
autosomal dominant Emery-Dreifuss muscular dystrophy 4 | 510
colon cancer 4 | 1,478
cystic fibrosis 4 | 1,696
juvenile dermatomyositis 4 | 1,187
sarcoidosis 4 | 370
substance-related disorder 4 | 162
Schizophrenia 3 | 1,160
acute quadriplegic myopathy 3 | 1,158
primary pancreatic ductal adenocarcinoma 3 | 1,109

Tissue

Endocrine System 32 | 18,159
Blood and immune system 31 | 16,909
Digestive Tract 31 | 17,369
Male tissues 31 | 17,142
Liver and Pancreas 30 | 16,750
Nervous System 30 | 16,725
Skin and soft tissues 30 | 17,230
Urinary Tract 30 | 16,678
Female tissues 29 | 17,400
Respiratory system 29 | 16,393
Cardiovascular System 28 | 15,192

Target Family

Non-IDG 19 | 12,091
Enzyme 12 | 4,145
Kinase 3 | 634
GPCR 1 | 408

Reactome Pathway

Glucagon signaling in metaboli... 35 | 35
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 GNG8 Tdark Non-IDG -2.17483 154.8 34
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 GNG10 Tdark Non-IDG 0.16 0.62 18
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 GNG5 Tbio Non-IDG -0.57807 4.05 87
Adenylate cyclase type 6 ADCY6 Tchem Enzyme -2.05332 113.7 111
Protein ALEX GNAS Tbio Non-IDG -2.63356 1389.7 509
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 GNG12 Tbio Non-IDG -0.39851 2.26 42
Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas GNAS Tbio Non-IDG -2.63356 1389.7 509
Adenylate cyclase type 4 ADCY4 Tbio Enzyme -2.04603 107.6 156