Development Level

Tbio 82 | 11,651
Tdark 17 | 6,593
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 9 | 979
embryonic lethality prior to o... 3 | 239
embryonic lethality prior to t... 3 | 278
increased grip strength 2 | 41
male infertility 2 | 123
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal heart morphology 1 | 162
abnormal retina morphology 1 | 71
abnormal snout morphology 1 | 23
absent spleen 1 | 3
decreased body weight 1 | 161
decreased circulating sodium l... 1 | 22
decreased neutrophil cell numb... 1 | 42
decreased red blood cell distr... 1 | 41
decreased spleen weight 1 | 10
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hyperactivity 1 | 148
increased circulating free fat... 1 | 20

Disease

Carcinoma 65 | 11,493
ovarian cancer 50 | 8,520
lung cancer 41 | 4,740
osteosarcoma 38 | 7,950
medulloblastoma, large-cell 33 | 6,241
group 3 medulloblastoma 31 | 4,104
psoriasis 31 | 6,694
Breast cancer 29 | 3,578
atypical teratoid / rhabdoid tumor 28 | 5,112
glioblastoma 25 | 5,792
Kidney cancer 24 | 2,613
intraductal papillary-mucinous neoplasm (IPMN) 21 | 3,291
Multiple myeloma 20 | 1,332
primitive neuroectodermal tumor 18 | 3,035
Cancer 17 | 2,499
invasive ductal carcinoma 17 | 2,951
astrocytic glioma 16 | 2,597
malignant mesothelioma 16 | 3,232
non-small cell lung cancer 16 | 2,890
oligodendroglioma 16 | 2,850
breast carcinoma 15 | 1,638
ependymoma 15 | 4,679
Pick disease 14 | 1,894
intraductal papillary-mucinous carcinoma (IPMC) 14 | 2,989
Waldenstrons macroglobulinemia 13 | 765
dermatomyositis 13 | 966
intraductal papillary-mucinous adenoma (IPMA) 13 | 2,955
lung adenocarcinoma 13 | 2,716
pancreatic cancer 12 | 2,398
adult high grade glioma 11 | 3,801
ductal carcinoma in situ 11 | 1,745
group 4 medulloblastoma 10 | 1,855
acute quadriplegic myopathy 9 | 1,158
colon cancer 9 | 1,478
pancreatic carcinoma 9 | 562
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Male infertility 8 | 206
juvenile dermatomyositis 8 | 1,187
Rheumatoid arthritis 7 | 1,191
acute myeloid leukemia 7 | 783
cutaneous lupus erythematosus 7 | 1,057
tuberculosis 7 | 2,010
Astrocytoma, Pilocytic 6 | 3,081
Infertility 6 | 188
Schizophrenia 6 | 1,160
cystic fibrosis 6 | 1,696
diabetes mellitus 6 | 1,728
Amyotrophic lateral sclerosis 5 | 451
adrenocortical carcinoma 5 | 1,428
hepatocellular carcinoma 5 | 547
lung carcinoma 5 | 2,843
nasopharyngeal carcinoma 5 | 1,058
non primary Sjogren syndrome sicca 5 | 891
pediatric high grade glioma 5 | 1,064
pituitary cancer 5 | 1,972
progressive supranuclear palsy 5 | 676
spina bifida 5 | 1,074
subependymal giant cell astrocytoma 5 | 2,287
Atopic dermatitis 4 | 952
Breast Neoplasms 4 | 445
Chikungunya 4 | 16
Cleft Palate 4 | 271
Hereditary spherocytosis type 5 4 | 12
Liver cancer 4 | 604
Mammary Neoplasms 4 | 425
Wilms Tumor 4 | 28
astrocytoma 4 | 1,146
non-small cell lung carcinoma 4 | 317
ulcerative colitis 4 | 1,819
Alzheimer's disease 3 | 658
Autosomal recessive predisposition 3 | 1,442
Bipolar Disorder 3 | 666
Connective tissue disease 3 | 62
Endometriosis 3 | 540
HIV Infections 3 | 102
Intellectual disability 3 | 1,016
Klinefelter's syndrome 3 | 56
Lupus erythematosus 3 | 57
NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE 3 | 4
Nephrotic syndrome, idiopathic, steroid-resistant 3 | 4
gastric cancer 3 | 459
hereditary spastic paraplegia 3 | 318
sarcoidosis 3 | 370
sonic hedgehog group medulloblastoma 3 | 467
tuberculosis and treatment for 6 months 3 | 409
Cockayne syndrome 2 | 60
Depressive disorder 2 | 409
Down syndrome 2 | 499
Endometrial cancer 2 | 311
Leukemia 2 | 104
Major Depressive Disorder 2 | 301
Malaria 2 | 160
Mental Depression 2 | 333
Mood Disorders 2 | 184
Polycystic ovary syndrome 2 | 360
Psychotic Disorders 2 | 151
gastric carcinoma 2 | 807
medulloblastoma 2 | 720
posterior fossa group B ependymoma 2 | 416
primary pancreatic ductal adenocarcinoma 2 | 1,109

Tissue

Endocrine System 99 | 18,159
Digestive Tract 97 | 17,369
Female tissues 97 | 17,400
Blood and immune system 96 | 16,909
Nervous System 95 | 16,725
Male tissues 94 | 17,142
Respiratory system 94 | 16,393
Skin and soft tissues 94 | 17,230
Liver and Pancreas 93 | 16,750
Urinary Tract 93 | 16,678
Cardiovascular System 92 | 15,192

Target Family

Non-IDG 70 | 12,091
Enzyme 23 | 4,145
Epigenetic 5 | 242
Kinase 1 | 634
Transcription Factor 1 | 1,400

Reactome Pathway

Gene Silencing by RNA 100 | 100
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Protein argonaute-2 AGO2 Tbio Non-IDG -2.97243 867.1 202
Nuclear pore complex protein Nup50 NUP50 Tbio Non-IDG -1.18445 15.9 270
Protein argonaute-1 AGO1 Tbio Non-IDG -2.22336 158.4 203
Trinucleotide repeat-containing gene 6C protein TNRC6C Tbio Non-IDG -0.67756 3.07 30
DNA-directed RNA polymerase II subunit RPB11-a POLR2J Tbio Enzyme -1.43224 29.3 213
Microprocessor complex subunit DGCR8 DGCR8 Tbio Non-IDG -2.46439 274.8 239
Nucleoporin p58/p45 NUP58 Tdark Non-IDG -0.69756 4.39 42
Trinucleotide repeat-containing gene 6A protein TNRC6A Tbio Non-IDG -2.08032 118.3 77
DNA-directed RNA polymerase II subunit RPB7 POLR2G Tbio Enzyme -1.77350 60.4 174
Nuclear pore glycoprotein p62 NUP62 Tbio Non-IDG -1.80390 62.5 241