Development Level

Tbio 23 | 11,445
Tdark 4 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

embryonic lethality prior to t... 4 | 278
decreased vertical activity 2 | 208
enlarged heart 2 | 210
prenatal lethality prior to he... 2 | 87
abnormal behavior 1 | 298
abnormal embryo size 1 | 220
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal liver morphology 1 | 17
abnormal pericardium morpholog... 1 | 26
abnormal retina morphology 1 | 71
abnormal spleen morphology 1 | 55
abnormal whole-body plethysmog... 1 | 4
cardiovascular system phenotyp... 1 | 36
decreased basophil cell number 1 | 16
decreased body weight 1 | 161
decreased circulating amylase ... 1 | 28
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased heart rate variabili... 1 | 13
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular vol... 1 | 79
decreased total body fat amoun... 1 | 207
edema 1 | 59
embryonic lethality prior to o... 1 | 239
enlarged spleen 1 | 41
hydrometra 1 | 53
hyperactivity 1 | 148
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased vertical activity 1 | 24
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
tremors 1 | 39

Disease

Carcinoma 20 | 11,493
osteosarcoma 15 | 7,950
ovarian cancer 15 | 8,520
psoriasis 13 | 6,694
adult high grade glioma 10 | 3,801
medulloblastoma, large-cell 9 | 6,241
Breast cancer 8 | 3,578
Erythrokeratodermia variabilis 8 | 10
Kidney cancer 8 | 2,613
interstitial cystitis 8 | 2,312
lung adenocarcinoma 8 | 2,716
lung cancer 8 | 4,740
malignant mesothelioma 8 | 3,232
Oculodentodigital dysplasia 7 | 14
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,291
invasive ductal carcinoma 7 | 2,951
non-small cell lung cancer 7 | 2,890
Autosomal recessive predisposition 6 | 1,442
Cancer 6 | 2,499
atypical teratoid / rhabdoid tumor 6 | 5,112
diabetes mellitus 6 | 1,728
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,955
pancreatic cancer 6 | 2,398
spina bifida 6 | 1,074
Cataract 5 | 297
Clouston syndrome 5 | 9
Nonsyndromic deafness 5 | 142
Palmoplantar keratosis 5 | 74
Sensorineural hearing loss 5 | 106
acute quadriplegic myopathy 5 | 1,158
group 3 medulloblastoma 5 | 4,104
lung carcinoma 5 | 2,843
primitive neuroectodermal tumor 5 | 3,035
subependymal giant cell astrocytoma 5 | 2,287
Alopecia 4 | 115
Astrocytoma, Pilocytic 4 | 3,081
Deafness, autosomal recessive 1A 4 | 4
Dull intelligence 4 | 645
Epilepsy 4 | 792
Erythema 4 | 58
Flushing 4 | 60
Hyperkeratosis, generalized 4 | 14
Hypertension 4 | 396
Hypertensive disease 4 | 292
Intellectual disability 4 | 1,016
Lens Opacities 4 | 231
Low intelligence 4 | 645
Mental Retardation 4 | 645
Mental deficiency 4 | 645
Neurodegenerative disease 4 | 414
Neuropathy 4 | 261
Poor school performance 4 | 645
Schizophrenia 4 | 1,160
Small head 4 | 374
astrocytic glioma 4 | 2,597
esophageal adenocarcinoma 4 | 737
gastric carcinoma 4 | 807
pituitary cancer 4 | 1,972
ulcerative colitis 4 | 1,819
Atopic dermatitis 3 | 952
Autistic Disorder 3 | 364
Bart-Pumphrey syndrome 3 | 4
Charcot-Marie-Tooth disease 3 | 62
Conductive hearing loss 3 | 123
Congenital pes cavus 3 | 88
DEAFNESS, AUTOSOMAL RECESSIVE 1A (disorder) 3 | 3
Deafness 3 | 198
Down syndrome 3 | 499
Dystrophic fingernails 3 | 18
Enlarged vestibular aqueduct 3 | 10
Fine hair 3 | 42
Frontal bossing 3 | 157
Hearing loss, progressive sensorineural 3 | 23
Heart disease 3 | 306
Infantile onset 3 | 238
Kidney disease 3 | 430
Low Vision 3 | 174
Lung Neoplasms 3 | 232
Myopia 3 | 176
Nail dysplasia 3 | 52
Pick disease 3 | 1,894
Sensorineural Hearing Loss (disorder) 3 | 284
Short stature 3 | 531
Skin Neoplasms 3 | 69
Sparse eyelashes 3 | 31
Sparse hair 3 | 59
Thin, sparse hair 3 | 59
Visual Impairment 3 | 174
X- linked recessive 3 | 110
breast carcinoma 3 | 1,638
cystic fibrosis 3 | 1,696
dermatomyositis 3 | 966
ductal carcinoma in situ 3 | 1,745
facioscapulohumeral dystrophy 3 | 288
juvenile dermatomyositis 3 | 1,187
primary pancreatic ductal adenocarcinoma 3 | 1,109
tuberculosis 3 | 2,010

Tissue

Endocrine System 29 | 18,159
Urinary Tract 28 | 16,678
Female tissues 27 | 17,400
Digestive Tract 26 | 17,369
Liver and Pancreas 26 | 16,750
Skin and soft tissues 26 | 17,230
Blood and immune system 25 | 16,909
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Respiratory system 23 | 16,393
Cardiovascular System 22 | 15,192

Target Family

Non-IDG 28 | 12,091
Kinase 1 | 634

Reactome Pathway

Gap junction trafficking and r... 29 | 29
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Gap junction delta-2 protein GJD2 Tbio Non-IDG -2.48933 326.9 192
Gap junction alpha-3 protein GJA3 Tbio Non-IDG -2.14059 135.1 171
Clathrin heavy chain 2 CLTCL1 Tbio Non-IDG -1.29555 21.3 39
Gap junction alpha-8 protein GJA8 Tbio Non-IDG -2.81282 660.2 196
Clathrin heavy chain 1 CLTC Tbio Non-IDG -1.66258 38.8 231
Gap junction alpha-4 protein GJA4 Tbio Non-IDG -2.27043 180.6 231
Gap junction alpha-5 protein GJA5 Tbio Non-IDG -2.59423 377.5 194
Gap junction beta-2 protein GJB2 Tbio Non-IDG -3.17642 1514.7 242
Gap junction beta-3 protein GJB3 Tbio Non-IDG -2.13572 133.9 212
Gap junction alpha-10 protein GJA10 Tdark Non-IDG 0.15 0.90 51