Development Level

Tbio 24 | 10,625
Tchem 7 | 1,890
Tdark 5 | 7,003
Tclin 3 | 602

IMPC Term

preweaning lethality, complete... 5 | 633
increased monocyte cell number 2 | 27
preweaning lethality, incomple... 2 | 260
abnormal coat/hair pigmentatio... 1 | 54
abnormal retinal pigmentation 1 | 61
abnormal rib morphology 1 | 28
abnormal snout morphology 1 | 18
abnormal vibrissa morphology 1 | 17
brachydactyly 1 | 2
decreased B cell number 1 | 30
decreased CD8-positive, alpha-... 1 | 26
decreased Ly6C high monocyte n... 1 | 18
decreased NK T cell number 1 | 28
decreased T cell number 1 | 31
decreased T-helper cell number 1 | 4
decreased alpha-beta T cell nu... 1 | 12
decreased body length 1 | 108
decreased bone mineral content 1 | 157
decreased erythrocyte cell num... 1 | 43
decreased hematocrit 1 | 25
decreased hemoglobin content 1 | 53
decreased lean body mass 1 | 195
decreased mature B cell number 1 | 25
decreased startle reflex 1 | 48
embryonic lethality prior to t... 1 | 187
enlarged heart 1 | 111
increased CD4-positive, CD25-p... 1 | 18
increased CD4-positive, alpha ... 1 | 15
increased KLRG1+ CD4 alpha bet... 1 | 5
increased KLRG1-positive CD4-p... 1 | 3
increased Ly6C low monocyte nu... 1 | 8
increased caudal vertebrae num... 1 | 8
increased circulating alkaline... 1 | 119
increased effector memory CD4-... 1 | 15
increased effector memory CD8-... 1 | 14
increased gamma-delta T cell n... 1 | 16
increased or absent threshold ... 1 | 128
increased total body fat amoun... 1 | 57
thrombocytosis 1 | 23
tremors 1 | 34
vertebral transformation 1 | 12

Disease

psoriasis 15 | 6,685
ovarian cancer 14 | 8,484
glioblastoma 13 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 13 | 3,289
osteosarcoma 13 | 7,933
Cancer 10 | 2,346
atypical teratoid / rhabdoid tumor 8 | 4,369
lung cancer 8 | 4,466
medulloblastoma, large-cell 8 | 6,234
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,795
Vitamin K deficiency hemorrhagic disease 7 | 11
lung carcinoma 7 | 2,844
malignant mesothelioma 7 | 3,162
pediatric high grade glioma 7 | 2,712
Chondrodysplasia punctata 6 | 41
Thrombosis 6 | 42
intraductal papillary-mucinous adenoma (IPMA) 6 | 2,956
invasive ductal carcinoma 6 | 2,950
lung adenocarcinoma 6 | 2,713
pancreatic cancer 6 | 2,300
pilocytic astrocytoma 6 | 3,086
primitive neuroectodermal tumor 6 | 3,031
Mucopolysaccharidosis 5 | 24
Thromboembolism 5 | 12
Thrombophilia 5 | 36
Vascular disease 5 | 281
cystic fibrosis 5 | 1,665
diabetes mellitus 5 | 1,663
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
non-small cell lung cancer 5 | 2,798
posterior fossa group A ependymoma 5 | 1,511
tuberculosis 5 | 1,557
Breast cancer 4 | 3,094
Factor X deficiency 4 | 5
Hemophilia B 4 | 11
Metachromatic leukodystrophy 4 | 13
Mucosulfatidosis 4 | 5
Pick disease 4 | 1,893
Protein C deficiency 4 | 19
group 3 medulloblastoma 4 | 2,254
oligodendroglioma 4 | 2,849
subependymal giant cell astrocytoma 4 | 2,287
Alzheimer's disease 3 | 644
Asthma 3 | 349
Atherosclerosis 3 | 275
Blood Coagulation Disorders 3 | 8
Cerebrovascular disease 3 | 231
Coronary artery disease 3 | 240
Disseminated intravascular coagulation 3 | 32
Factor VII deficiency 3 | 5
Factor VIII deficiency 3 | 10
Factor XI deficiency 3 | 9
Leukodystrophy 3 | 30
Liver disease 3 | 219
Multiple myeloma 3 | 1,327
Obesity 3 | 616
Pulmonary Embolism 3 | 45
Venous Thrombosis 3 | 21
Von Willebrand's disease 3 | 19
X-linked ichthyosis 3 | 18
active Crohn's disease 3 | 918
acute myeloid leukemia 3 | 780
adrenocortical carcinoma 3 | 1,427
adult high grade glioma 3 | 2,148
ependymoma 3 | 2,514
medulloblastoma 3 | 1,524
non primary Sjogren syndrome sicca 3 | 840
pancreatic carcinoma 3 | 567
Animal Mammary Neoplasms 2 | 136
Arthritis 2 | 248
Atrial Fibrillation 2 | 110
Blood protein disease 2 | 10
Endocarditis 2 | 18
Fatty Liver 2 | 48
Heart disease 2 | 279
Hepatitis B 2 | 103
Hypertension 2 | 287
Hypogonadism 2 | 70
IGA Glomerulonephritis 2 | 454
Kidney disease 2 | 396
Mammary Neoplasms, Experimental 2 | 150
Ocular albinism 2 | 29
Thrombocytopenia 2 | 105
Thrombophlebitis 2 | 16
Typhoid fever 2 | 22
Venous Thromboembolism 2 | 34
Waldenstrons macroglobulinemia 2 | 765
active ulcerative colitis 2 | 477
acute quadriplegic myopathy 2 | 1,157
astrocytic glioma 2 | 2,241
astrocytoma 2 | 1,493
atypical teratoid/rhabdoid tumor 2 | 1,095
dermatomyositis 2 | 933
ductal carcinoma in situ 2 | 1,745
inclusion-cell disease 2 | 15
interstitial cystitis 2 | 2,299
nasopharyngeal carcinoma 2 | 1,056
primary pancreatic ductal adenocarcinoma 2 | 1,271
tuberculosis and treatment for 3 months 2 | 327
tuberculosis and treatment for 6 months 2 | 686

Tissue

Blood and immune system 39 | 17,995
Digestive Tract 39 | 18,473
Endocrine System 39 | 18,512
Female tissues 39 | 18,647
Liver and Pancreas 39 | 18,136
Male tissues 39 | 17,969
Nervous System 39 | 18,561
Skin and soft tissues 39 | 18,115
Urinary Tract 39 | 18,444
Cardiovascular System 38 | 17,958
Respiratory system 38 | 17,484

Target Family

Enzyme 27 | 4,146
Non-IDG 10 | 11,971
Kinase 2 | 634

Reactome Pathway

Gamma carboxylation, hypusine ... 39 | 39
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Elongation factor 2 EEF2 Tchem Non-IDG -2.93803 911.5 347
Arylsulfatase I ARSI Tbio Enzyme -1.93924 88.6 108
Arylsulfatase H ARSH Tbio Enzyme -2.12798 119.1 77
Arylsulfatase J ARSJ Tdark Enzyme -0.07048 1.18 17
Arylsulfatase F ARSF Tbio Enzyme -0.46364 2.97 126
Sulfatase-modifying factor 1 SUMF1 Tbio Enzyme -2.17638 149.5 134
DnaJ homolog subfamily C member 24 DNAJC24 Tbio Non-IDG -0.61394 4.38 0
Osteocalcin BGLAP Tbio Non-IDG -3.89171 7292.7 532
Sulfatase-modifying factor 2 SUMF2 Tbio Enzyme -3.27011 1887.5 51
Arylsulfatase B ARSB Tbio Enzyme -2.42590 280.1 198