Development Level

Tbio 4 | 11,445
Tchem 3 | 1,598
Tclin 3 | 613

IMPC Phenotype

abnormal behavior 1 | 298
abnormal femur morphology 1 | 14
decreased leukocyte cell numbe... 1 | 73
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499

Disease

osteosarcoma 9 | 7,950
Cancer 8 | 2,499
Carcinoma 8 | 11,493
Breast cancer 7 | 3,578
glioblastoma 7 | 5,792
ovarian cancer 7 | 8,520
Kidney cancer 6 | 2,613
psoriasis 6 | 6,694
atypical teratoid / rhabdoid tumor 5 | 5,112
invasive ductal carcinoma 5 | 2,951
medulloblastoma, large-cell 5 | 6,241
Adenocarcinoma 4 | 122
Autosomal recessive predisposition 4 | 1,442
Breast Neoplasms 4 | 445
Mammary Neoplasms 4 | 425
Neoplasm Metastasis 4 | 168
Rheumatoid arthritis 4 | 1,191
Schizophrenia 4 | 1,160
breast carcinoma 4 | 1,638
juvenile dermatomyositis 4 | 1,187
lung adenocarcinoma 4 | 2,716
lung cancer 4 | 4,740
non-small cell lung cancer 4 | 2,890
oligodendroglioma 4 | 2,850
Alcoholic Intoxication, Chronic 3 | 289
Carcinoma, Hepatocellular 3 | 228
Carcinoma, Squamous Cell 3 | 110
Colorectal Neoplasms 3 | 243
DOID:2627 3 | 94
Disease Progression 3 | 136
Failure to gain weight 3 | 365
Hypoplastic mandible condyle 3 | 275
Liver carcinoma 3 | 240
Mandibular hypoplasia 3 | 275
Micrognathism 3 | 275
Myopia 3 | 176
Neoplasm Invasiveness 3 | 161
Noonan syndrome 3 | 34
Pediatric failure to thrive 3 | 365
Pick disease 3 | 1,894
Prostatic Neoplasms 3 | 495
Squamous cell carcinoma 3 | 129
Stomach Neoplasms 3 | 300
astrocytic glioma 3 | 2,597
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
ependymoma 3 | 4,679
interstitial cystitis 3 | 2,312
pancreatic cancer 3 | 2,398
pancreatic carcinoma 3 | 562
Acquired scoliosis 2 | 281
Adenocarcinoma of lung 2 | 142
Adenoma 2 | 167
Animal Mammary Neoplasms 2 | 136
Arthritis 2 | 290
Bladder Neoplasm 2 | 112
Broad flat nasal bridge 2 | 236
Byzanthine arch palate 2 | 194
Colonic Neoplasms 2 | 142
Congenital Epicanthus 2 | 177
Curvature of spine 2 | 282
Delayed bone age 2 | 136
Dermatitis 2 | 157
Diarrhea 2 | 253
Downward slant of palpebral fissure 2 | 158
Endometrial cancer 2 | 311
Endometriosis 2 | 540
Esophageal carcinoma 2 | 16
Fatigue 2 | 182
Frontal bossing 2 | 157
Gaucher disease type 1 2 | 180
High forehead 2 | 102
Joint hyperflexibility 2 | 78
Kidney disease 2 | 430
Leukemia 2 | 104
Lung Neoplasms 2 | 232
Major Depressive Disorder 2 | 301
Mammary Neoplasms, Experimental 2 | 154
Melanocytic nevus 2 | 43
Nasal bridge wide 2 | 236
Noncancerous mole 2 | 28
Pectus excavatum 2 | 100
Polycystic ovary syndrome 2 | 360
Sensorineural Hearing Loss (disorder) 2 | 284
Somatic mutation 2 | 61
Tall forehead 2 | 102
Triangular face 2 | 58
Unipolar Depression 2 | 250
Urinary Bladder Neoplasms 2 | 114
Urinary bladder cancer 2 | 36
Vascular disease 2 | 319
Ventricular Septal Defects 2 | 119
chronic lymphosyte leukemia 2 | 204
cystic fibrosis 2 | 1,696
hepatocellular carcinoma 2 | 547
pediatric high grade glioma 2 | 1,064
pituitary cancer 2 | 1,972
progressive supranuclear palsy 2 | 676
spina bifida 2 | 1,074
tuberculosis 2 | 2,010

Tissue

Blood and immune system 10 | 16,909
Cardiovascular System 10 | 15,192
Digestive Tract 10 | 17,369
Endocrine System 10 | 18,159
Female tissues 10 | 17,400
Liver and Pancreas 10 | 16,750
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678

Target Family

Non-IDG 5 | 12,091
Kinase 4 | 634
Enzyme 1 | 4,145

Reactome Pathway

GAB1 signalosome 10 | 10
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
GRB2-associated-binding protein 1 GAB1 Tbio Non-IDG -1.55563 50.4 268
Paxillin PXN Tbio Non-IDG -2.99437 902.9 1251
Pro-epidermal growth factor EGF Tbio Non-IDG -3.75933 4903.2 978
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 PAG1 Tbio Non-IDG -1.69647 50.1 216
Growth factor receptor-bound protein 2 GRB2 Tchem Non-IDG -3.02404 981.4 501
Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 Tchem Kinase -2.51919 316.4 758
Proto-oncogene tyrosine-protein kinase Src SRC Tclin Kinase -4.00292 9201.7 1455
Tyrosine-protein phosphatase non-receptor type 11 PTPN11 Tchem Enzyme -3.11032 1400.0 1077
Epidermal growth factor receptor EGFR Tclin Kinase -4.02650 10013.1 6418
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform PIK3CA Tclin Kinase -3.04988 1076.8 484