Development Level

Tbio 10 | 10,625
Tchem 10 | 1,890
Tdark 3 | 7,003
Tclin 2 | 602

IMPC Term

embryonic lethality prior to o... 1 | 148
embryonic lethality prior to t... 1 | 187

Disease

ovarian cancer 19 | 8,484
Cancer 16 | 2,346
medulloblastoma, large-cell 16 | 6,234
glioblastoma 14 | 5,572
osteosarcoma 14 | 7,933
psoriasis 14 | 6,685
lung cancer 12 | 4,466
non-small cell lung cancer 11 | 2,798
primitive neuroectodermal tumor 11 | 3,031
Breast cancer 10 | 3,094
group 3 medulloblastoma 10 | 2,254
malignant mesothelioma 10 | 3,162
pediatric high grade glioma 10 | 2,712
adrenocortical carcinoma 9 | 1,427
intraductal papillary-mucinous neoplasm (IPMN) 9 | 3,289
lung adenocarcinoma 9 | 2,713
invasive ductal carcinoma 8 | 2,950
Endometriosis 7 | 535
atypical teratoid / rhabdoid tumor 7 | 4,369
atypical teratoid/rhabdoid tumor 7 | 1,095
ductal carcinoma in situ 7 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,988
pilocytic astrocytoma 7 | 3,086
Atopic dermatitis 6 | 944
colon cancer 6 | 1,475
nasopharyngeal carcinoma 6 | 1,056
Waldenstrons macroglobulinemia 5 | 765
breast carcinoma 5 | 1,614
oligodendroglioma 5 | 2,849
pancreatic cancer 5 | 2,300
primary Sjogren syndrome 5 | 789
ulcerative colitis 5 | 2,087
active Crohn's disease 4 | 918
astrocytoma 4 | 1,493
medulloblastoma 4 | 1,524
posterior fossa group A ependymoma 4 | 1,511
sonic hedgehog group medulloblastoma 4 | 1,482
Carcinoma 3 | 2,147
IGA Glomerulonephritis 3 | 454
Liver carcinoma 3 | 217
Mammary Neoplasms 3 | 410
Multiple myeloma 3 | 1,327
Pick disease 3 | 1,893
Polycystic Ovary Syndrome 3 | 332
Retinoblastoma 3 | 14
dermatomyositis 3 | 933
ependymoma 3 | 2,514
interstitial cystitis 3 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
subependymal giant cell astrocytoma 3 | 2,287
Asthma 2 | 349
Disease Progression 2 | 125
Intellectual disability 2 | 573
Melanoma 2 | 261
Peripheral Neuropathy 2 | 303
astrocytic glioma 2 | 2,241
cystic fibrosis and chronic rhinosinusitis 2 | 213
esophageal adenocarcinoma 2 | 737
facioscapulohumeral dystrophy 2 | 286
inflammatory breast cancer 2 | 404
juvenile dermatomyositis 2 | 1,189
ovarian neoplasm 2 | 97
tuberculosis 2 | 1,557
Acute myeloid leukemia, disease 1 | 16
Adenocarcinoma 1 | 115
Adenoid Cystic Carcinoma 1 | 99
Bladder Neoplasm 1 | 109
Cardiovascular system disease 1 | 194
Chronic Lymphocytic Leukemia 1 | 242
Colonic Neoplasms 1 | 126
Dental fluorosis 1 | 16
Fetal valproate syndrome 1 | 4
Focal glomerulosclerosis 1 | 22
Glioma 1 | 65
Hodgkin's disease 1 | 18
Hyperhomocysteinemia 1 | 34
Kaposi's sarcoma 1 | 20
Kidney disease 1 | 396
Leukemia 1 | 88
Lung Neoplasms 1 | 171
Malignant tumor of ovary 1 | 25
Meier-Gorlin syndrome 1 | 12
Metastatic Prostate Carcinoma 1 | 18
Microcephaly 1 | 149
Muscle Weakness 1 | 92
Nephroblastoma 1 | 45
Neuroblastoma 1 | 78
Neurodegenerative disease 1 | 383
Peripheral T-cell lymphoma 1 | 24
Poor school performance 1 | 13
Primary cutaneous T-cell lymphoma 1 | 24
Salivary Gland Neoplasms 1 | 45
Seckel syndrome 1 | 34
Seizure Adverse Event 1 | 19
Squamous cell carcinoma 1 | 94
Squamous cell carcinoma of the head and neck 1 | 24
Urinary bladder cancer 1 | 31
progressive supranuclear palsy 1 | 674
tuberculosis and treatment for 3 months 1 | 327
tuberculosis and treatment for 6 months 1 | 686

Tissue

Blood and immune system 25 | 17,995
Cardiovascular System 25 | 17,958
Digestive Tract 25 | 18,473
Endocrine System 25 | 18,512
Female tissues 25 | 18,647
Liver and Pancreas 25 | 18,136
Male tissues 25 | 17,969
Nervous System 25 | 18,561
Respiratory system 25 | 17,484
Skin and soft tissues 25 | 18,115
Urinary Tract 25 | 18,444

Target Family

Non-IDG 13 | 11,971
Transcription Factor 6 | 1,400
Kinase 3 | 634
Enzyme 2 | 4,146
Epigenetic 1 | 242

Reactome Pathway

G0 and Early G1 25 | 25
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Proliferating cell nuclear antigen PCNA Tchem Non-IDG -1.10426 11.5 1277
DNA topoisomerase 2-alpha TOP2A Tclin Enzyme -2.81595 662.3 551
Protein lin-9 homolog LIN9 Tbio Non-IDG -1.88736 79.3 89
Dual specificity tyrosine-phosphorylation-regulated kinase 1A DYRK1A Tchem Kinase -2.62311 466.9 306
Cell division control protein 6 homolog CDC6 Tchem Non-IDG -2.48727 321.6 473
Histone deacetylase 1 HDAC1 Tclin Epigenetic -2.97422 866.1 1107
Retinoblastoma-like protein 1 RBL1 Tbio Non-IDG -2.61434 376.7 290
Histone-binding protein RBBP4 RBBP4 Tbio Non-IDG -1.66776 51.8 276
Myb-related protein B MYBL2 Tbio Transcription Factor -2.15851 159.3 268
G1/S-specific cyclin-E1 CCNE1 Tchem Non-IDG -2.40805 239.2 741