Development Level

Tbio 30 | 11,445
Tchem 10 | 1,598
Tdark 5 | 6,588
Tclin 4 | 613

Collection

Kinase: IDG Consortium (Target... 1 | 125

IMPC Phenotype

abnormal bone structure 4 | 187
increased heart weight 4 | 62
increased startle reflex 4 | 112
decreased vertical activity 3 | 208
preweaning lethality, incomple... 3 | 499
abnormal behavior 1 | 298
abnormal spleen morphology 1 | 55
abnormal testis morphology 1 | 43
decreased circulating chloride... 1 | 30
decreased fasted circulating g... 1 | 65
decreased lean body mass 1 | 135
decreased prepulse inhibition 1 | 82
decreased startle reflex 1 | 75
enlarged heart 1 | 210
enlarged spleen 1 | 41
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
male infertility 1 | 123
preweaning lethality, complete... 1 | 979
small kidney 1 | 16
small superior vagus ganglion 1 | 74
small testis 1 | 58

Disease

Carcinoma 30 | 11,493
medulloblastoma, large-cell 28 | 6,241
glioblastoma 27 | 5,792
ovarian cancer 25 | 8,520
osteosarcoma 24 | 7,950
ependymoma 22 | 4,679
atypical teratoid / rhabdoid tumor 21 | 5,112
psoriasis 20 | 6,694
primitive neuroectodermal tumor 19 | 3,035
Astrocytoma, Pilocytic 18 | 3,081
adult high grade glioma 18 | 3,801
group 3 medulloblastoma 18 | 4,104
lung cancer 18 | 4,740
lung carcinoma 17 | 2,843
oligodendroglioma 16 | 2,850
invasive ductal carcinoma 15 | 2,951
astrocytic glioma 14 | 2,597
Breast cancer 13 | 3,578
interstitial cystitis 13 | 2,312
lung adenocarcinoma 13 | 2,716
non-small cell lung cancer 13 | 2,890
subependymal giant cell astrocytoma 13 | 2,287
Kidney cancer 12 | 2,613
Pick disease 11 | 1,894
pituitary cancer 11 | 1,972
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
malignant mesothelioma 10 | 3,232
astrocytoma 9 | 1,146
pancreatic cancer 9 | 2,398
Depressive disorder 8 | 409
breast carcinoma 8 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
ulcerative colitis 8 | 1,819
Liver cancer 7 | 604
Obesity 7 | 678
ductal carcinoma in situ 7 | 1,745
group 4 medulloblastoma 7 | 1,855
Acquired metabolic disease 6 | 336
Bipolar Disorder 6 | 666
Cancer 6 | 2,499
Hypertension 6 | 396
Mental Depression 6 | 333
Mood Disorders 6 | 184
Rheumatoid arthritis 6 | 1,191
Schizophrenia 6 | 1,160
Substance Withdrawal Syndrome 6 | 55
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
ACTH-secreting pituitary adenoma 5 | 9
Alcoholic Intoxication, Chronic 5 | 289
Asthma 5 | 385
Hypertensive disease 5 | 292
Intellectual disability 5 | 1,016
diabetes mellitus 5 | 1,728
juvenile dermatomyositis 5 | 1,187
primary Sjogren syndrome 5 | 735
Acromegaly 4 | 51
Adenoma 4 | 167
Adrenal gland cancer 4 | 12
Attention deficit hyperactivity disorder 4 | 278
Biliary tract cancer 4 | 19
Bone cancer 4 | 16
Brachydactyly 4 | 156
Bronchiectasis 4 | 64
Cardiomegaly 4 | 116
Carney complex 4 | 25
Cerebrovascular disease 4 | 238
Cervix carcinoma 4 | 10
Colorectal Neoplasms 4 | 243
Cushing's syndrome 4 | 48
Duchenne muscular dystrophy 4 | 601
Epilepsy 4 | 792
Fibrodysplasia ossificans progressiva 4 | 17
Fibrous dysplasia 4 | 15
Hyperphosphatemia 4 | 32
Hyperthyroidism 4 | 53
Hypoparathyroidism 4 | 41
Hypothyroidism 4 | 122
Kidney disease 4 | 430
Liver Cirrhosis, Experimental 4 | 769
Major Depressive Disorder 4 | 301
McCune Albright syndrome 4 | 19
Multiple Endocrine Neoplasia Type 1 4 | 29
Ossifying fibroma 4 | 15
Parkinson's disease 4 | 392
Peripheral vascular disease 4 | 87
Pituitary adenoma 4 | 38
Plummer's disease 4 | 11
Polycystic ovary syndrome 4 | 360
Primary pigmented nodular adrenocortical disease 4 | 13
Pseudohypoparathyroidism 4 | 18
Small intestine cancer 4 | 12
Stomach cancer 4 | 30
Thyroid cancer 4 | 36
Unipolar Depression 4 | 250
active Crohn's disease 4 | 922
colon cancer 4 | 1,478
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
substance-related disorder 4 | 162
tuberculosis 4 | 2,010

Tissue

Digestive Tract 46 | 17,369
Endocrine System 46 | 18,159
Blood and immune system 45 | 16,909
Female tissues 44 | 17,400
Skin and soft tissues 44 | 17,230
Male tissues 43 | 17,142
Nervous System 43 | 16,725
Liver and Pancreas 41 | 16,750
Urinary Tract 41 | 16,678
Cardiovascular System 40 | 15,192
Respiratory system 40 | 16,393

Target Family

Non-IDG 31 | 12,091
Enzyme 8 | 4,145
Kinase 7 | 634
GPCR 3 | 408

Reactome Pathway

G alpha (z) signalling events 49 | 49
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Adenylate cyclase type 8 ADCY8 Tbio Enzyme -2.04645 112.4 147
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 GNG8 Tdark Non-IDG -2.17483 154.8 34
Protein kinase C beta type PRKCB Tchem Kinase -2.00437 93.5 598
Adenylate cyclase type 7 ADCY7 Tbio Enzyme -1.68806 49.1 114
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 GNG10 Tdark Non-IDG 0.16 0.62 18
Regulator of G-protein signaling protein-like RGSL1 Tdark Non-IDG -0.63255 3.56 2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 GNG5 Tbio Non-IDG -0.57807 4.05 87
Guanine nucleotide-binding protein G(t) subunit alpha-3 GNAT3 Tbio Non-IDG -2.28370 189.3 111
Adenylate cyclase type 6 ADCY6 Tchem Enzyme -2.05332 113.7 111
Protein ALEX GNAS Tbio Non-IDG -2.63356 1389.7 509