Development Level

Tbio 10 | 10,625
Tchem 3 | 1,890

IMPC Term

preweaning lethality, complete... 3 | 633
abnormal cornea morphology 1 | 24
abnormal embryo size 1 | 112
abnormal retina morphology 1 | 100
abnormal tail morphology 1 | 17
corneal opacity 1 | 25
decreased grip strength 1 | 123
decreased kidney weight 1 | 7
decreased spleen weight 1 | 13
embryonic lethality prior to t... 1 | 187
enlarged lymph nodes 1 | 27
impaired pupillary reflex 1 | 14
increased circulating HDL chol... 1 | 63
increased total body fat amoun... 1 | 57
limb grasping 1 | 35
narrow eye opening 1 | 15
no spontaneous movement 1 | 1

Disease

Cancer 5 | 2,346
Cleft Lip 4 | 91
Cleft palate 4 | 125
Craniosynostosis 4 | 47
ovarian cancer 4 | 8,484
psoriasis 4 | 6,685
Mammary Neoplasms 3 | 410
diabetes mellitus 3 | 1,663
ependymoma 3 | 2,514
group 3 medulloblastoma 3 | 2,254
lung cancer 3 | 4,466
malignant mesothelioma 3 | 3,162
medulloblastoma, large-cell 3 | 6,234
osteosarcoma 3 | 7,933
Achondroplasia 2 | 20
Acrocephalosyndactylia 2 | 15
Alzheimer's disease 2 | 644
Breast cancer 2 | 3,094
Congenital diaphragmatic hernia 2 | 43
Craniofacial Abnormalities 2 | 147
Diaphragmatic Hernia 2 | 40
Hypospadias 2 | 65
Kallmann Syndrome 2 | 33
Klinefelter's syndrome 2 | 59
LADD syndrome 2 | 9
Liver carcinoma 2 | 217
Parkinson's disease 2 | 364
Polycystic Ovary Syndrome 2 | 332
Polydactyly 2 | 93
Prostatic Neoplasms 2 | 471
Renal agenesis 2 | 25
Synostosis 2 | 18
astrocytic glioma 2 | 2,241
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
invasive ductal carcinoma 2 | 2,950
lung adenocarcinoma 2 | 2,713
lung carcinoma 2 | 2,844
non-small cell lung cancer 2 | 2,798
ulcerative colitis 2 | 2,087
Acquired immunodeficiency syndrome 1 | 164
Ankylosis 1 | 25
Antley-Bixler syndrome 1 | 15
CHARGE syndrome 1 | 23
Calcinosis 1 | 62
Cardiofaciocutaneous syndrome 1 | 15
Cardiomegaly 1 | 66
Cardiovascular Abnormalities 1 | 7
Costello syndrome 1 | 16
DiGeorge syndrome 1 | 46
Diabetic Retinopathy 1 | 53
Duane Retraction Syndrome 1 | 9
Esophageal atresia 1 | 25
Fanconi syndrome 1 | 14
Fibrous dysplasia 1 | 15
Gastrointestinal system disease 1 | 50
Gestational Diabetes 1 | 17
Gingival fibromatosis 1 | 13
Glioma 1 | 65
Gliosis 1 | 16
Hemangioma 1 | 35
Hemangiopericytoma 1 | 6
Hypercalcemia 1 | 37
Hyperostosis 1 | 16
Hyperparathyroidism 1 | 43
Hyperphosphatemia 1 | 32
Hypochondroplasia 1 | 11
Hypogonadism 1 | 70
Hypophosphatemia 1 | 31
Idiopathic scoliosis 1 | 29
Intestinal atresia 1 | 7
LEOPARD Syndrome 1 | 20
Liver Cirrhosis 1 | 101
Liver Cirrhosis, Experimental 1 | 108
Matthew-Wood syndrome 1 | 10
McCune Albright syndrome 1 | 19
Nephrotic Syndrome 1 | 48
Nerve Degeneration 1 | 73
Neurofibromatosis 1 | 37
Noonan Syndrome 1 | 33
Opitz-GBBB syndrome 1 | 19
Oral Submucous Fibrosis 1 | 18
Osteoarthritis 1 | 96
Osteomalacia 1 | 28
Piebaldism 1 | 11
Prenatal Exposure Delayed Effects 1 | 9
Pulmonary Fibrosis 1 | 66
Pulmonary valve stenosis 1 | 10
Radioulnar synostosis 1 | 13
Retinal Degeneration 1 | 49
Retinal detachment 1 | 33
Rickets 1 | 42
Sensorineural hearing loss 1 | 107
Thrombocythemia, Essential 1 | 12
Tooth agenesis 1 | 36
Type 1 diabetes mellitus 1 | 101
Uremia 1 | 19
Velocardiofacial syndrome 1 | 45
Vesicoureteral reflux 1 | 28
Wolf-Hirschhorn syndrome 1 | 32
chronic kidney disease 1 | 90

Tissue

Blood and immune system 13 | 17,995
Cardiovascular System 13 | 17,958
Endocrine System 13 | 18,512
Female tissues 13 | 18,647
Liver and Pancreas 13 | 18,136
Nervous System 13 | 18,561
Skin and soft tissues 13 | 18,115
Digestive Tract 12 | 18,473
Male tissues 12 | 17,969
Urinary Tract 12 | 18,444
Respiratory system 9 | 17,484

Target Family

Non-IDG 13 | 11,971

Reactome Pathway

FGFRL1 modulation of FGFR1 sig... 13 | 13
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibroblast growth factor 5 FGF5 Tbio Non-IDG -2.00731 99.9 143
Fibroblast growth factor 10 FGF10 Tbio Non-IDG -2.51373 345.1 271
Fibroblast growth factor 2 FGF2 Tchem Non-IDG -3.97848 10115.4 658
Fibroblast growth factor 18 FGF18 Tbio Non-IDG -1.83412 76.6 133
Fibroblast growth factor 22 FGF22 Tbio Non-IDG -1.09135 15.2 159
Sprouty-related, EVH1 domain-containing protein 2 SPRED2 Tbio Non-IDG -1.05316 18.3 91
Sprouty-related, EVH1 domain-containing protein 1 SPRED1 Tbio Non-IDG -1.86169 72.5 242
Fibroblast growth factor receptor-like 1 FGFRL1 Tbio Non-IDG -1.45637 34.7 171
Fibroblast growth factor 4 FGF4 Tchem Non-IDG -2.58324 381.0 264
Fibroblast growth factor 3 FGF3 Tbio Non-IDG -2.27975 189.5 81