Development Level

Tbio 11 | 11,651
Tchem 1 | 1,388

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal embryo size 1 | 220
abnormal retina morphology 1 | 71
abnormal tail morphology 1 | 25
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
hemorrhage 1 | 23
increased circulating choleste... 1 | 66
limb grasping 1 | 41
no spontaneous movement 1 | 1

Disease

Cancer 5 | 2,499
Carcinoma 5 | 11,493
Cleft Lip 4 | 141
Cleft Palate 4 | 271
group 3 medulloblastoma 4 | 4,104
ovarian cancer 4 | 8,520
psoriasis 4 | 6,694
Autosomal recessive predisposition 3 | 1,442
Delayed bone age 3 | 136
Depressive disorder 3 | 409
Osteoporosis 3 | 363
diabetes mellitus 3 | 1,728
ependymoma 3 | 4,679
lung cancer 3 | 4,740
malignant mesothelioma 3 | 3,232
medulloblastoma, large-cell 3 | 6,241
osteosarcoma 3 | 7,950
Abnormality of body height 2 | 13
Abnormality of the voice 2 | 46
Absence of pubertal development 2 | 17
Absence of secondary sex characteristics 2 | 22
Achondroplasia 2 | 21
Anosmia 2 | 22
Anterior hypopituitarism 2 | 18
Anxiety 2 | 136
Anxiety disease 2 | 113
Bipolar Disorder 2 | 666
Breast Neoplasms 2 | 445
Breast cancer 2 | 3,578
Broad flat nasal bridge 2 | 236
Carcinoma, Hepatocellular 2 | 228
Congenital hypoplasia of breast 2 | 25
Congenital hypoplasia of ovary 2 | 30
Congenital hypoplasia of penis 2 | 176
Craniofacial Abnormalities 2 | 151
Craniosynostosis 2 | 74
Cryptorchidism 2 | 296
Decreased bone mineral density Z score 2 | 31
Decreased fertility 2 | 33
Decreased testosterone in males 2 | 28
Delayed Puberty 2 | 97
Diaphragmatic Hernia 2 | 40
Erectile abnormalities 2 | 16
Erectile dysfunction 2 | 32
Eunuchoid habitus 2 | 14
Female hypogonadism syndrome 2 | 25
Generalized osteopenia 2 | 99
Gynecomastia 2 | 64
Hemangioma 2 | 69
Hernia, Diaphragmatic 2 | 40
Hypogonadism 2 | 173
Hypogonadism, Isolated Hypogonadotropic 2 | 71
Hypogonadotropic hypogonadism 2 | 89
Hypoplastic mandible condyle 2 | 275
Hypoplastic ovary 2 | 30
Hypothalamic gonadotropin-releasing hormone deficiency 2 | 14
Increased female libido 2 | 13
Infantile uterus 2 | 23
Kallmann Syndrome 2 (disorder) 2 | 18
Kallmann syndrome 2 | 33
Klinefelter's syndrome 2 | 56
Liver carcinoma 2 | 240
Mammary Neoplasms 2 | 425
Mandibular hypoplasia 2 | 275
Micrognathism 2 | 275
Nasal bridge wide 2 | 236
Non-obstructive azoospermia 2 | 21
Osteopenia 2 | 99
Parkinson's disease 2 | 392
Polycystic ovary syndrome 2 | 360
Polydactyly 2 | 107
Primary physiologic amenorrhea 2 | 55
Secondary physiologic amenorrhea 2 | 32
Seizures 2 | 596
Sense of smell impaired 2 | 21
Short stature 2 | 531
Small testicle 2 | 75
Sparse body hair 2 | 32
Synostosis 2 | 15
Testicular hypogonadism 2 | 21
Wide spaced nipples 2 | 46
astrocytic glioma 2 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
non-small cell lung cancer 2 | 2,890
Ankylosis 1 | 28
Antley-Bixler syndrome 1 | 16
Bowed and upward slanting eyebrows 1 | 41
Cardiovascular Abnormalities 1 | 31
Decreased muscle mass 1 | 28
Generalized hypotonia 1 | 37
Gingival fibromatosis 1 | 14
Hernias, Diaphragmatic, Congenital 1 | 17
Hyperostosis 1 | 18
Hypochondroplasia 1 | 10
Oral Submucous Fibrosis 1 | 20
Rib fusion 1 | 16
Thanatophoric dysplasia 1 | 7
Thick, flared eyebrows 1 | 41
Thin hypoplastic alae nasi 1 | 51
Widely spaced teeth 1 | 31

Tissue

Endocrine System 11 | 18,159
Blood and immune system 10 | 16,909
Digestive Tract 10 | 17,369
Female tissues 10 | 17,400
Male tissues 10 | 17,142
Nervous System 10 | 16,725
Respiratory system 10 | 16,393
Skin and soft tissues 10 | 17,230
Urinary Tract 10 | 16,678
Liver and Pancreas 9 | 16,750
Cardiovascular System 7 | 15,192

Target Family

Non-IDG 12 | 12,091

Reactome Pathway

FGFRL1 modulation of FGFR1 sig... 12 | 12
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Fibroblast growth factor 22 FGF22 Tbio Non-IDG -1.15836 16.5 186
Fibroblast growth factor 2 FGF2 Tchem Non-IDG -4.00542 10573.5 798
Fibroblast growth factor 3 FGF3 Tbio Non-IDG -2.29270 192.7 118
Sprouty-related, EVH1 domain-containing protein 2 SPRED2 Tbio Non-IDG -1.13996 20.0 106
Fibroblast growth factor receptor-like 1 FGFRL1 Tbio Non-IDG -1.53083 37.2 212
Fibroblast growth factor 4 FGF4 Tbio Non-IDG -2.60388 394.1 327
Fibroblast growth factor 5 FGF5 Tbio Non-IDG -2.07061 109.8 192
Fibroblast growth factor 18 FGF18 Tbio Non-IDG -1.89822 84.6 146
Sprouty-related, EVH1 domain-containing protein 1 SPRED1 Tbio Non-IDG -1.93963 79.1 299
Fibroblast growth factor 23 FGF23 Tbio Non-IDG -3.19500 1726.4 296