Development Level

Tdark 57 | 7,003
Tbio 9 | 10,625
Tclin 6 | 602
Tchem 3 | 1,890

IMPC Phenotype

abnormal behavior 1 | 226
abnormal femur morphology 1 | 14
preweaning lethality, complete... 1 | 633

Disease

osteosarcoma 17 | 7,933
interstitial cystitis 15 | 2,299
psoriasis 15 | 6,685
lung cancer 12 | 4,473
Cancer 11 | 2,346
periodontitis 11 | 269
ulcerative colitis 11 | 2,087
chronic lymphosyte leukemia 10 | 232
Multiple myeloma 9 | 1,327
lung adenocarcinoma 9 | 2,714
lung carcinoma 9 | 2,844
tuberculosis 9 | 1,563
cutaneous lupus erythematosus 8 | 1,056
non-small cell lung cancer 8 | 2,798
ovarian cancer 8 | 8,491
Blastic phase chronic myeloid leukemia 6 | 58
Chronic Myelocytic Leukemia Accelerated Phase 6 | 59
pancreatic cancer 6 | 2,300
Amebiasis 5 | 22
Leukemia 5 | 88
Lymphoma 5 | 57
diabetes mellitus 5 | 1,663
glioblastoma 5 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
invasive ductal carcinoma 5 | 2,950
medulloblastoma, large-cell 5 | 6,234
mucosa-associated lymphoid tissue lymphoma 5 | 480
primary Sjogren syndrome 5 | 788
Breast cancer 4 | 3,098
Chronic phase chronic myeloid leukemia 4 | 45
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 4 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 4 | 47
Waldenstrons macroglobulinemia 4 | 764
cystic fibrosis and chronic rhinosinusitis 4 | 213
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
primary pancreatic ductal adenocarcinoma 4 | 1,271
Arthritis 3 | 248
Chronic obstructive pulmonary disease 3 | 147
Kidney disease 3 | 397
Myositis 3 | 24
Rheumatoid Arthritis 3 | 1,170
astrocytoma 3 | 1,493
chronic lymphocytic leukemia 3 | 244
colon cancer 3 | 1,475
cystic fibrosis 3 | 1,670
esophageal adenocarcinoma 3 | 737
juvenile dermatomyositis 3 | 1,189
non-small cell lung carcinoma 3 | 413
pilocytic astrocytoma 3 | 3,086
subependymal giant cell astrocytoma 3 | 2,287
Allergic hypersensitivity disease 2 | 123
Asthma 2 | 349
Cherubism 2 | 14
Down syndrome 2 | 548
Gastrointestinal system disease 2 | 50
Human immunodeficiency virus infectious disease 2 | 129
Hypersensitivity reaction type II disease 2 | 235
IGA Glomerulonephritis 2 | 454
Immunoglobulin kappa light chain deficiency 2 | 2
Kappa-Chain Deficiency 2 | 2
Lung disease 2 | 136
Lupus Erythematosus, Systemic 2 | 73
Lupus erythematosus 2 | 80
Multiple Sclerosis 2 | 498
Primary immunodeficiency disease 2 | 52
Thrombocytopenia 2 | 105
Vasculitis 2 | 64
dermatomyositis 2 | 966
gastric carcinoma 2 | 832
inflammatory breast cancer 2 | 404
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
medulloblastoma 2 | 1,524
nephrosclerosis 2 | 329
oligodendroglioma 2 | 2,849
pediatric high grade glioma 2 | 2,712
posterior fossa group A ependymoma 2 | 1,511
systemic lupus erythematosus 2 | 172
tuberculosis and treatment for 6 months 2 | 686
Anemia 1 | 252
Bladder Neoplasm 1 | 109
Cerebrovascular disease 1 | 231
Colitis 1 | 46
Colonic Neoplasms 1 | 126
Heart disease 1 | 279
Hypertension 1 | 293
Inflammatory bowel disease 1 | 142
Malaria 1 | 140
Mesothelioma 1 | 40
Osteoporosis 1 | 259
Pain agnosia 1 | 99
Peripheral T-cell lymphoma 1 | 24
Severe Combined Immunodeficiency 1 | 46
Sjogren's syndrome 1 | 23
Status Epilepticus 1 | 85
Stomach Neoplasms 1 | 282
Urinary bladder cancer 1 | 34
active ulcerative colitis 1 | 477
facioscapulohumeral dystrophy 1 | 286
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
pulmonary arterial hypertension 1 | 36

Tissue

Blood and immune system 60 | 17,994
Digestive Tract 60 | 18,472
Female tissues 60 | 18,646
Respiratory system 60 | 17,483
Skin and soft tissues 60 | 18,114
Liver and Pancreas 59 | 18,135
Urinary Tract 59 | 18,443
Cardiovascular System 57 | 17,957
Endocrine System 56 | 18,511
Nervous System 56 | 18,560
Male tissues 54 | 17,968

Target Family

Non-IDG 68 | 11,969
Kinase 7 | 634

Reactome Pathway

FCGR activation 75 | 75
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ig lambda-6 chain C region IGLC6 Tdark Non-IDG -1.81183 228.7 0
Tyrosine-protein kinase SYK SYK Tchem Kinase -3.11789 1349.3 1026
T-cell surface glycoprotein CD3 zeta chain CD247 Tbio Non-IDG -2.59549 375.1 667
Tyrosine-protein kinase Yes YES1 Tclin Kinase -2.02315 100.2 381
Tyrosine-protein kinase Lyn LYN Tclin Kinase -2.82112 659.3 521
Immunoglobulin heavy variable 3-7 IGHV3-7 Tdark Non-IDG 0.00000 0
Immunoglobulin heavy variable 3-33 IGHV3-33 Tdark Non-IDG 0.00000 0
Proto-oncogene tyrosine-protein kinase Src SRC Tclin Kinase -3.98540 8801.0 1257
Immunoglobulin heavy variable 1-46 IGHV1-46 Tdark Non-IDG 0.00000 0
Immunoglobulin heavy variable 1-69 IGHV1-69 Tdark Non-IDG 0.00000 0