Development Level

Tdark 70 | 6,588
Tbio 9 | 11,445
Tclin 6 | 613
Tchem 3 | 1,598

IMPC Phenotype

preweaning lethality, complete... 2 | 979
abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal femur morphology 1 | 14
abnormal gait 1 | 69
abnormal maxilla morphology 1 | 17
decreased hemoglobin content 1 | 68
decreased large unstained cell... 1 | 11
decreased lean body mass 1 | 135
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
increased blood urea nitrogen ... 1 | 48
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
increased spleen weight 1 | 10
increased total body fat amoun... 1 | 134
preweaning lethality, incomple... 1 | 499
thrombocytopenia 1 | 56

Disease

osteosarcoma 17 | 7,950
interstitial cystitis 16 | 2,312
psoriasis 16 | 6,694
periodontitis 12 | 293
tuberculosis 12 | 2,010
ulcerative colitis 12 | 1,819
lung cancer 11 | 4,740
Cancer 10 | 2,499
lung adenocarcinoma 10 | 2,716
Multiple myeloma 9 | 1,332
chronic lymphosyte leukemia 9 | 204
non-small cell lung cancer 9 | 2,890
Carcinoma 8 | 11,493
lung carcinoma 8 | 2,843
ovarian cancer 8 | 8,520
cutaneous lupus erythematosus 7 | 1,057
Blastic phase chronic myeloid leukemia 6 | 58
Chronic Myelocytic Leukemia Accelerated Phase 6 | 59
mucosa-associated lymphoid tissue lymphoma 6 | 484
pancreatic cancer 6 | 2,398
Liver Cirrhosis, Experimental 5 | 769
diabetes mellitus 5 | 1,728
glioblastoma 5 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
invasive ductal carcinoma 5 | 2,951
medulloblastoma, large-cell 5 | 6,241
primary Sjogren syndrome 5 | 735
Breast cancer 4 | 3,578
Chronic Lymphocytic Leukemia 4 | 262
Chronic phase chronic myeloid leukemia 4 | 45
Kidney disease 4 | 430
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 4 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 4 | 47
Waldenstrons macroglobulinemia 4 | 765
cystic fibrosis and chronic rhinosinusitis 4 | 214
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
non-small cell lung carcinoma 4 | 317
primary pancreatic ductal adenocarcinoma 4 | 1,109
Amebiasis 3 | 21
Arthritis 3 | 290
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Chronic obstructive pulmonary disease 3 | 184
Isolated growth hormone deficiency 3 | 30
Leukemia 3 | 104
Lymphoma 3 | 81
Lymphoproliferative syndrome 3 | 58
Myositis 3 | 30
astrocytoma 3 | 1,146
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
esophageal adenocarcinoma 3 | 737
group 4 medulloblastoma 3 | 1,855
juvenile dermatomyositis 3 | 1,187
subependymal giant cell astrocytoma 3 | 2,287
Agammaglobulinemia 2 | 34
Allergic hypersensitivity disease 2 | 126
Anemia 2 | 365
Asthma 2 | 385
Bipolar Disorder 2 | 666
Cherubism 2 | 13
Down syndrome 2 | 499
Gastrointestinal system disease 2 | 54
Heart disease 2 | 306
Hereditary spherocytosis type 1 2 | 23
Human immunodeficiency virus infectious disease 2 | 138
Hypersensitivity reaction type II disease 2 | 253
Immunoglobulin kappa light chain deficiency 2 | 2
Immunologic Deficiency Syndromes 2 | 113
Kappa-Chain Deficiency 2 | 2
Kidney cancer 2 | 2,613
Lung disease 2 | 142
Lupus Erythematosus, Systemic 2 | 67
Multiple Sclerosis 2 | 540
Recurrent respiratory infections 2 | 141
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
Stomach Neoplasms 2 | 300
Systemic lupus erythematosus 2 | 194
Thrombocytopenia 2 | 197
Vasculitis 2 | 80
dermatomyositis 2 | 966
gastric carcinoma 2 | 807
inflammatory breast cancer 2 | 286
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
nephrosclerosis 2 | 333
oligodendroglioma 2 | 2,850
pediatric high grade glioma 2 | 1,064
Adult T-Cell Lymphoma/Leukemia 1 | 30
Alcoholic Intoxication 1 | 34
Breast Neoplasms 1 | 445
Colorectal Neoplasms 1 | 243
Hepatitis C 1 | 94
Leukemia-Lymphoma, Adult T-Cell 1 | 30
Liver disease 1 | 237
Mammary Neoplasms 1 | 425
Neutropenia 1 | 72
facioscapulohumeral dystrophy 1 | 288
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
sarcoidosis 1 | 370

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Non-IDG 81 | 12,091
Kinase 7 | 634

Reactome Pathway

FCGR activation 88 | 88
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 1D-39 IGKV1D-39 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 1-16 IGKV1-16 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 1-12 IGKV1-12 Tdark Non-IDG 0.00000 0
Immunoglobulin lambda constant 1 IGLC1 Tbio Non-IDG -1.96217 230.7 0
Immunoglobulin lambda constant 6 IGLC6 Tdark Non-IDG -1.96217 230.7 0
Immunoglobulin lambda variable 1-36 IGLV1-36 Tdark Non-IDG 0.00000 0
T-cell surface glycoprotein CD3 gamma chain CD3G Tclin Non-IDG -2.34430 223.5 239
Immunoglobulin kappa variable 2-29 IGKV2-29 Tdark Non-IDG 0.00000 0
Immunoglobulin heavy variable 4-34 IGHV4-34 Tdark Non-IDG 0.00000 0