Development Level

Tdark 57 | 7,003
Tbio 9 | 10,625
Tclin 6 | 602
Tchem 3 | 1,890

IMPC Term

abnormal behavior 1 | 226
abnormal femur morphology 1 | 14
preweaning lethality, complete... 1 | 633

Disease

osteosarcoma 17 | 7,933
interstitial cystitis 15 | 2,299
psoriasis 15 | 6,685
lung cancer 12 | 4,466
Cancer 11 | 2,346
periodontitis 11 | 269
ulcerative colitis 11 | 2,087
chronic lymphosyte leukemia 10 | 232
lung adenocarcinoma 9 | 2,713
lung carcinoma 9 | 2,844
tuberculosis 9 | 1,557
Multiple myeloma 8 | 1,327
cutaneous lupus erythematosus 8 | 1,056
non-small cell lung cancer 8 | 2,798
ovarian cancer 8 | 8,484
Blastic phase chronic myeloid leukemia 6 | 58
Chronic Myelocytic Leukemia Accelerated Phase 6 | 59
pancreatic cancer 6 | 2,300
Amebiasis 5 | 22
Leukemia 5 | 88
Lymphoma 5 | 56
diabetes mellitus 5 | 1,663
glioblastoma 5 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
invasive ductal carcinoma 5 | 2,950
medulloblastoma, large-cell 5 | 6,234
mucosa-associated lymphoid tissue lymphoma 5 | 480
primary Sjogren syndrome 5 | 789
Breast cancer 4 | 3,094
Chronic phase chronic myeloid leukemia 4 | 45
Philadelphia Chromosome Positive Chronic Myelocytic Leukemia 4 | 45
Philadelphia chromosome-positive acute lymphoblastic leukemia 4 | 47
Waldenstrons macroglobulinemia 4 | 765
cystic fibrosis and chronic rhinosinusitis 4 | 213
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
primary pancreatic ductal adenocarcinoma 4 | 1,271
Arthritis 3 | 248
Chronic Lymphocytic Leukemia 3 | 242
Chronic obstructive pulmonary disease 3 | 146
Kidney disease 3 | 396
Myositis 3 | 24
Rheumatoid Arthritis 3 | 1,160
astrocytoma 3 | 1,493
colon cancer 3 | 1,475
esophageal adenocarcinoma 3 | 737
juvenile dermatomyositis 3 | 1,189
non-small cell lung carcinoma 3 | 413
pilocytic astrocytoma 3 | 3,086
subependymal giant cell astrocytoma 3 | 2,287
Allergic hypersensitivity disease 2 | 123
Asthma 2 | 349
Cherubism 2 | 14
Down syndrome 2 | 548
Gastrointestinal system disease 2 | 50
Human immunodeficiency virus infectious disease 2 | 92
Hypersensitivity reaction type II disease 2 | 235
IGA Glomerulonephritis 2 | 454
Kappa-Chain Deficiency 2 | 2
Lung disease 2 | 132
Lupus Erythematosus, Systemic 2 | 73
Lupus erythematosus 2 | 80
Multiple Sclerosis 2 | 498
Primary immunodeficiency disease 2 | 52
Thrombocytopenia 2 | 105
Vasculitis 2 | 64
cystic fibrosis 2 | 1,665
dermatomyositis 2 | 933
gastric carcinoma 2 | 832
inflammatory breast cancer 2 | 404
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
medulloblastoma 2 | 1,524
nephrosclerosis 2 | 329
oligodendroglioma 2 | 2,849
pediatric high grade glioma 2 | 2,712
posterior fossa group A ependymoma 2 | 1,511
systemic lupus erythematosus 2 | 156
tuberculosis and treatment for 6 months 2 | 686
Atherosclerosis 1 | 275
Bladder Neoplasm 1 | 109
Cerebrovascular disease 1 | 231
Colitis 1 | 46
Colonic Neoplasms 1 | 126
Coronary artery disease 1 | 240
Heart disease 1 | 279
Hypertension 1 | 287
Inflammatory bowel disease 1 | 142
Malaria 1 | 140
Mesothelioma 1 | 40
Osteoporosis 1 | 257
Pain agnosia 1 | 99
Peripheral Neuropathy 1 | 303
Peripheral T-cell lymphoma 1 | 24
Severe Combined Immunodeficiency 1 | 46
Sjogren's syndrome 1 | 23
Status Epilepticus 1 | 85
Stomach Neoplasms 1 | 282
active Crohn's disease 1 | 918
active ulcerative colitis 1 | 477
head and neck cancer and chronic obstructive pulmonary disease 1 | 237
pulmonary arterial hypertension 1 | 36

Tissue

Blood and immune system 60 | 17,995
Digestive Tract 60 | 18,473
Female tissues 60 | 18,647
Respiratory system 60 | 17,484
Skin and soft tissues 60 | 18,115
Liver and Pancreas 59 | 18,136
Urinary Tract 59 | 18,444
Cardiovascular System 57 | 17,958
Endocrine System 56 | 18,512
Nervous System 56 | 18,561
Male tissues 54 | 17,969

Target Family

Non-IDG 68 | 11,971
Kinase 7 | 634

Reactome Pathway

FCGR activation 75 | 75
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
Ig lambda-7 chain C region IGLC7 Tdark Non-IDG 228.7 0
Immunoglobulin lambda variable 1-44 IGLV1-44 Tdark Non-IDG 0.00000 0
High affinity immunoglobulin gamma Fc receptor I FCGR1A Tchem Non-IDG -2.98035 1006.3 583
Immunoglobulin heavy variable 1-2 IGHV1-2 Tdark Non-IDG 0.00000 0
Low affinity immunoglobulin gamma Fc region receptor II-a FCGR2A Tbio Non-IDG -2.87960 775.0 717
Immunoglobulin kappa variable 3-15 IGKV3-15 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 2-28 IGKV2-28 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 2D-30 IGKV2D-30 Tdark Non-IDG 0.00000 0
Ig gamma-1 chain C region IGHG1 Tbio Non-IDG 0.00000 0