Development Level

Tbio 88 | 11,445
Tdark 5 | 6,588
Tchem 1 | 1,598

IMPC Phenotype

abnormal bone structure 1 | 187
decreased body length 1 | 101
impaired pupillary reflex 1 | 26
increased or absent threshold ... 1 | 101
increased startle reflex 1 | 112
prolonged QT interval 1 | 38

Disease

ovarian cancer 32 | 8,520
lung cancer 30 | 4,740
diabetes mellitus 27 | 1,728
Diamond-Blackfan anemia 25 | 31
Multiple myeloma 24 | 1,332
intraductal papillary-mucinous neoplasm (IPMN) 24 | 3,291
medulloblastoma, large-cell 21 | 6,241
osteosarcoma 16 | 7,950
Waldenstrons macroglobulinemia 14 | 765
Abnormality of the urinary system 13 | 21
Anemia 13 | 365
Anemia, Diamond-Blackfan 13 | 16
Anemia, Macrocytic 13 | 18
Cardiac Arrhythmia 13 | 103
Cardiac conduction abnormalities 13 | 78
Cleft Palate 13 | 271
Conduction disorder of the heart 13 | 79
Delayed Puberty 13 | 97
EKG abnormalities 13 | 78
Electrocardiogram abnormal 13 | 81
Electrocardiogram change 13 | 78
Fatigue 13 | 182
Hand deformities 13 | 32
Intermittent migraine headaches 13 | 68
Migraine Disorders 13 | 76
Pallor 13 | 40
Uranostaphyloschisis 13 | 167
genital abnormal 13 | 17
reproductive system abnormality 13 | 17
intraductal papillary-mucinous adenoma (IPMA) 12 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
psoriasis 12 | 6,694
Carcinoma 11 | 11,493
acute quadriplegic myopathy 11 | 1,158
atypical teratoid / rhabdoid tumor 11 | 5,112
sonic hedgehog group medulloblastoma 11 | 467
Breast cancer 10 | 3,578
cystic fibrosis 10 | 1,696
glioblastoma 10 | 5,792
Disease Progression 8 | 136
Stomach Neoplasms 8 | 300
malignant mesothelioma 8 | 3,232
oligodendroglioma 8 | 2,850
acute myeloid leukemia 7 | 783
group 3 medulloblastoma 7 | 4,104
invasive ductal carcinoma 7 | 2,951
Breast Neoplasms 6 | 445
Mammary Neoplasms 6 | 425
colon cancer 6 | 1,478
lung adenocarcinoma 6 | 2,716
mucosa-associated lymphoid tissue lymphoma 6 | 484
subependymal giant cell astrocytoma 6 | 2,287
Adenocarcinoma of lung 5 | 142
Disease Models, Animal 5 | 155
Reticulocytopenia 5 | 10
adult high grade glioma 5 | 3,801
astrocytoma 5 | 1,146
Astrocytoma, Pilocytic 4 | 3,081
Hereditary spherocytosis type 4 4 | 18
Infantile onset 4 | 238
Parkinson Disease 4 | 64
non-small cell lung cancer 4 | 2,890
pediatric high grade glioma 4 | 1,064
primitive neuroectodermal tumor 4 | 3,035
Animal Mammary Neoplasms 3 | 136
Cancer 3 | 2,499
Duchenne muscular dystrophy 3 | 601
Elevated red cell adenosine deaminase activity 3 | 3
Erythroid hypoplasia 3 | 3
Hypoplastic anemia 3 | 4
Hypoplastic mandible condyle 3 | 275
Irregular astigmatism 3 | 12
Mammary Neoplasms, Animal 3 | 136
Mammary Neoplasms, Experimental 3 | 154
Mandibular hypoplasia 3 | 275
Mean cell volume increased 3 | 5
Micrognathism 3 | 275
Polycystic ovary syndrome 3 | 360
Prostatic Neoplasms 3 | 495
Pure red-cell aplasia 3 | 4
Retinitis pigmentosa 49 3 | 14
Short stature 3 | 531
Shwachman-Diamond syndrome 3 | 17
Triphalangeal thumb 3 | 9
Ventricular Septal Defects 3 | 119
Weight Gain 3 | 100
astrocytic glioma 3 | 2,597
breast carcinoma 3 | 1,638
cutaneous lupus erythematosus 3 | 1,057
ependymoma 3 | 4,679
group 4 medulloblastoma 3 | 1,855
inflammatory breast cancer 3 | 286
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
primary pancreatic ductal adenocarcinoma 3 | 1,109
Hemoglobin low 2 | 124
Hypertension 2 | 396
adrenocortical carcinoma 2 | 1,428
glioblastoma multiforme 2 | 142
medulloblastoma 2 | 720
progressive supranuclear palsy 2 | 676

Tissue

Endocrine System 93 | 18,159
Blood and immune system 92 | 16,909
Digestive Tract 92 | 17,369
Male tissues 92 | 17,142
Skin and soft tissues 92 | 17,230
Cardiovascular System 91 | 15,192
Female tissues 91 | 17,400
Liver and Pancreas 91 | 16,750
Nervous System 91 | 16,725
Respiratory system 91 | 16,393
Urinary Tract 91 | 16,678

Target Family

Non-IDG 89 | 12,091
Enzyme 5 | 4,145

Reactome Pathway

Eukaryotic Translation Termina... 94 | 94
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
60S ribosomal protein L3 RPL3 Tbio Non-IDG -2.02901 103.9 190
40S ribosomal protein S19 RPS19 Tbio Non-IDG -3.14746 1380.8 267
60S ribosomal protein L36 RPL36 Tbio Non-IDG -1.62928 39.9 123
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A GSPT1 Tbio Enzyme -1.35573 22.8 99
60S ribosomal protein L35 RPL35 Tbio Non-IDG -1.30696 19.1 124
60S ribosomal protein L10 RPL10 Tbio Non-IDG -0.94919 8.10 191
60S ribosomal protein L26-like 1 RPL26L1 Tdark Non-IDG 0.30 0.50 77
60S ribosomal protein L13a RPL13A Tbio Non-IDG -1.64278 64.4 67
40S ribosomal protein S21 RPS21 Tbio Non-IDG -1.92202 82.6 72
60S ribosomal protein L38 RPL38 Tbio Non-IDG -1.40384 24.5 54