Development Level

Tbio 20 | 11,445
Tchem 6 | 1,598
Tclin 1 | 613
Tdark 1 | 6,588

IMPC Phenotype

decreased mean corpuscular vol... 3 | 79
embryonic lethality prior to o... 3 | 239
abnormal heart morphology 2 | 162
decreased circulating LDL chol... 2 | 38
decreased fasted circulating g... 2 | 65
decreased mean platelet volume 2 | 25
embryonic lethality prior to t... 2 | 278
enlarged heart 2 | 210
enlarged spleen 2 | 41
increased mean platelet volume 2 | 45
preweaning lethality, complete... 2 | 979
preweaning lethality, incomple... 2 | 499
abnormal bone structure 1 | 187
abnormal lens morphology 1 | 81
abnormal pericardium morpholog... 1 | 26
abnormal response to new envir... 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal skin coloration 1 | 25
abnormal spleen morphology 1 | 55
abnormal thymus morphology 1 | 7
anophthalmia 1 | 33
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased caudal vertebrae num... 1 | 53
decreased circulating HDL chol... 1 | 68
decreased circulating amylase ... 1 | 28
decreased circulating choleste... 1 | 93
decreased circulating iron lev... 1 | 32
decreased circulating magnesiu... 1 | 13
decreased erythrocyte cell num... 1 | 62
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased leukocyte cell numbe... 1 | 73
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular hem... 1 | 31
decreased threshold for audito... 1 | 26
edema 1 | 59
enlarged thymus 1 | 5
impaired glucose tolerance 1 | 75
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased glycosylated hemoglo... 1 | 1
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased red blood cell distr... 1 | 34
increased spleen weight 1 | 10
limb grasping 1 | 41

Disease

Carcinoma 17 | 11,493
ovarian cancer 15 | 8,520
medulloblastoma, large-cell 13 | 6,241
osteosarcoma 12 | 7,950
psoriasis 10 | 6,694
Breast cancer 9 | 3,578
glioblastoma 9 | 5,792
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
adult high grade glioma 7 | 3,801
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
Cancer 6 | 2,499
Kidney cancer 5 | 2,613
group 4 medulloblastoma 5 | 1,855
lung cancer 5 | 4,740
subependymal giant cell astrocytoma 5 | 2,287
Angiomyolipoma 4 | 18
Epilepsy 4 | 792
Kidney angiomyolipoma 4 | 8
Lymphangioleiomyomatosis 4 | 16
Renal Cell Carcinoma 4 | 214
Wolff-Parkinson-White syndrome 4 | 19
astrocytic glioma 4 | 2,597
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
Abdominal Pain 3 | 98
Autistic Disorder 3 | 364
Carcinoma, Squamous Cell 3 | 110
Focal cortical dysplasia of Taylor 3 | 3
Intellectual disability 3 | 1,016
Multiple myeloma 3 | 1,332
Pick disease 3 | 1,894
Squamous cell carcinoma 3 | 129
Tuberous sclerosis 3 | 19
adrenocortical carcinoma 3 | 1,428
colon cancer 3 | 1,478
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
malignant mesothelioma 3 | 3,232
non primary Sjogren syndrome sicca 3 | 891
oligodendroglioma 3 | 2,850
pituitary cancer 3 | 1,972
Abnormal behavior 2 | 52
Abnormality of female internal genitalia 2 | 13
Adenocarcinoma 2 | 122
Atelectasis 2 | 8
Birt-Hogg-Dube syndrome 2 | 11
Birthmark 2 | 35
Brain Diseases 2 | 24
Cafe-au-Lait Spots 2 | 37
Carcinoma, Hepatocellular 2 | 228
Carcinoma, Renal Cell 2 | 124
Cardiac rhabdomyoma 2 | 5
Cardiomegaly 2 | 116
Cardiomyopathies 2 | 110
Cerebral calcification 2 | 43
Cerebrovascular accident 2 | 63
Chest Pain 2 | 38
Coughing 2 | 25
Cystic kidney 2 | 30
Dyspnea 2 | 76
Electroencephalogram abnormal 2 | 101
Fibromatosis, Gingival 2 | 8
Globe disease 2 | 67
Glucose Intolerance 2 | 19
Glycogen storage disease 2 | 39
Hematuria 2 | 36
Hereditary gingival fibromatosis 2 | 8
Highly variable clinical phenotype 2 | 150
Highly variable phenotype and severity 2 | 150
Highly variable phenotype, even within families 2 | 150
Hypertension 2 | 396
Hypertrophy, Left Ventricular 2 | 24
Hypothyroidism 2 | 122
Idiopathic gingival hyperplasia 2 | 8
Impaired glucose tolerance 2 | 28
Infiltrate of lung 2 | 17
Insulin Resistance 2 | 72
Isolated cases 2 | 72
Kidney disease 2 | 430
Left Ventricular Hypertrophy 2 | 47
Liver carcinoma 2 | 240
Lymphadenopathy 2 | 62
Mouth Neoplasms 2 | 55
Pancreatic Neoplasm 2 | 85
Pancreatic Neoplasms 2 | 85
Peutz-Jeghers syndrome 2 | 21
Phenotypic variability 2 | 150
Precocious Puberty 2 | 28
Prominent back of the head 2 | 21
Prominent occiput 2 | 21
Pulmonary emphysema 2 | 48
Renal cyst 2 | 30
Sebaceous adenoma 2 | 26
Seizures 2 | 596
Skin tag 2 | 14
Specific learning disability 2 | 47
Stomach Neoplasms 2 | 300
West Syndrome 2 | 28
hypopigmented skin patch 2 | 59
medulloblastoma 2 | 720

Tissue

Cardiovascular System 28 | 15,192
Digestive Tract 28 | 17,369
Endocrine System 28 | 18,159
Female tissues 28 | 17,400
Male tissues 28 | 17,142
Skin and soft tissues 28 | 17,230
Blood and immune system 27 | 16,909
Liver and Pancreas 27 | 16,750
Nervous System 27 | 16,725
Respiratory system 27 | 16,393
Urinary Tract 27 | 16,678

Target Family

Non-IDG 14 | 12,091
Kinase 8 | 634
Enzyme 5 | 4,145
Transporter 1 | 473

Reactome Pathway

Energy dependent regulation of... 28 | 28
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Sodium-coupled neutral amino acid transporter 9 SLC38A9 Tbio Transporter -0.82795 8.59 27
Ras-related GTP-binding protein B RRAGB Tbio Non-IDG -1.40729 26.2 113
Ras-related GTP-binding protein C RRAGC Tbio Non-IDG -1.45388 30.6 200
Ras-related GTP-binding protein D RRAGD Tbio Non-IDG -0.96229 6.82 90
Ragulator complex protein LAMTOR5 LAMTOR5 Tbio Non-IDG -2.24915 162.8 99
Ragulator complex protein LAMTOR4 LAMTOR4 Tdark Non-IDG -0.19564 1.23 34
Ragulator complex protein LAMTOR2 LAMTOR2 Tbio Non-IDG -0.96319 9.78 81
5'-AMP-activated protein kinase subunit gamma-1 PRKAG1 Tbio Kinase -1.00162 9.02 293
Target of rapamycin complex subunit LST8 MLST8 Tbio Non-IDG -2.64631 429.3 360
Tuberin TSC2 Tbio Non-IDG -2.99381 1000.6 1632