Development Level

Tclin 9 | 602
Tchem 5 | 1,890
Tbio 1 | 10,625

Collection

Eligible non-olfactory GPCR Proteins 1 | 145

IMPC Term

decreased basophil cell number 1 | 11
decreased circulating alanine ... 1 | 53

Disease

osteosarcoma 10 | 7,933
Allergic rhinitis 7 | 92
Asthma 7 | 349
psoriasis 7 | 6,685
Asthma, Aspirin-Induced 6 | 13
ovarian cancer 6 | 8,492
Cervical ripening procedure 5 | 9
Hydatidiform mole, benign 5 | 9
Incomplete miscarriage 5 | 10
Induction of labor 5 | 10
Pregnancy with abortive outcome 5 | 12
pilocytic astrocytoma 5 | 3,086
Atopic dermatitis 4 | 944
Common cold 4 | 63
Crohn's disease 4 | 304
glioblastoma 4 | 5,572
lung carcinoma 4 | 2,844
Cancer 3 | 2,346
Drug allergy 3 | 36
Endometriosis 3 | 535
Physiological Sexual Disorders 3 | 4
Rhinitis 3 | 46
atypical teratoid / rhabdoid tumor 3 | 4,369
colon cancer 3 | 1,475
interstitial cystitis 3 | 2,299
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,289
invasive ductal carcinoma 3 | 2,950
lung cancer 3 | 4,473
tuberculosis 3 | 1,563
ulcerative colitis 3 | 2,087
Allergic hypersensitivity disease 2 | 123
Aorta Dextratransposition with Intact Ventricular Septum 2 | 6
Atherosclerosis 2 | 275
Breast cancer 2 | 3,099
Coarctation of aorta 2 | 6
Congenital Heart Defect Requiring Open Patent Ductus Arteriosus 2 | 6
Congenital atresia of the pulmonary valve 2 | 6
Congenital atresia of tricuspid valve 2 | 6
Cough 2 | 21
Ebstein's anomaly of tricuspid valve 2 | 6
Eosinophilia 2 | 65
Impotence 2 | 45
Inflammation 2 | 109
Multiple Sclerosis 2 | 498
Nasal congestion 2 | 24
Nasal discharge 2 | 26
Ocular hypertension 2 | 27
Postpartum hemorrhage 2 | 6
Pulmonary artery stenosis 2 | 6
Pulmonary hypertension 2 | 52
Tetralogy of Fallot 2 | 38
Urticaria 2 | 53
Vascular disease 2 | 281
acute myeloid leukemia 2 | 785
adrenocortical adenoma 2 | 134
adrenocortical carcinoma 2 | 1,427
adult high grade glioma 2 | 2,148
aldosterone-producing adenoma 2 | 664
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,988
lung adenocarcinoma 2 | 2,714
malignant mesothelioma 2 | 3,163
medulloblastoma 2 | 1,524
medulloblastoma, large-cell 2 | 6,234
non-small cell lung cancer 2 | 2,798
pediatric high grade glioma 2 | 2,712
posterior fossa group B ependymoma 2 | 1,530
primary Sjogren syndrome 2 | 789
pulmonary arterial hypertension 2 | 36
ASTHMA, ASPIRIN-INDUCED, SUSCEPTIBILITY TO 1 | 2
Adenocarcinoma 1 | 115
Animal Mammary Neoplasms 1 | 136
Ankylosing spondylitis 1 | 138
Arthritis, Experimental 1 | 39
Asthma management 1 | 20
Asthma, Nasal Polyps, And Aspirin Intolerance 1 | 2
Bipolar Disorder 1 | 266
Brain infarction 1 | 17
Drug-Induced Liver Injury 1 | 118
Gaucher disease type 3 1 | 76
Glaucoma 1 | 135
Human immunodeficiency virus infectious disease 1 | 129
Hyperalgesia 1 | 71
Infertility 1 | 163
Inflammatory bowel disease 1 | 142
Liver diseases 1 | 66
Lymphoma 1 | 57
Mammary Neoplasms, Experimental 1 | 150
Necrosis 1 | 51
Open-angle glaucoma 1 | 26
Primary pulmonary hypertension 1 | 7
Pulmonary Embolism 1 | 45
Squamous cell carcinoma 1 | 96
Stevens-Johnson syndrome 1 | 91
Trichomoniasis 1 | 9
active ulcerative colitis 1 | 477
cystic fibrosis and chronic rhinosinusitis 1 | 213
facioscapulohumeral dystrophy 1 | 286
glioblastoma multiforme 1 | 347
severe asthma 1 | 11

Tissue

Blood and immune system 15 | 17,995
Digestive Tract 15 | 18,473
Skin and soft tissues 15 | 18,115
Cardiovascular System 14 | 17,958
Endocrine System 14 | 18,512
Female tissues 14 | 18,647
Liver and Pancreas 14 | 18,136
Nervous System 14 | 18,561
Respiratory system 14 | 17,484
Urinary Tract 14 | 18,444
Male tissues 13 | 17,969

Target Family

GPCR 15 | 408

Reactome Pathway

Eicosanoid ligand-binding rece... 15 | 15
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prostaglandin D2 receptor 2 PTGDR2 Tchem GPCR -2.35437 249.5 398
Prostaglandin E2 receptor EP4 subtype PTGER4 Tclin GPCR -2.95863 922.9 216
Thromboxane A2 receptor TBXA2R Tclin GPCR -2.15292 118.2 105
Prostaglandin F2-alpha receptor PTGFR Tclin GPCR -2.01133 95.5 105
Prostaglandin E2 receptor EP3 subtype PTGER3 Tclin GPCR -2.78321 604.1 294
Prostaglandin E2 receptor EP2 subtype PTGER2 Tclin GPCR -1.21342 15.1 372
Prostacyclin receptor PTGIR Tclin GPCR -2.98778 898.0 168
Cysteinyl leukotriene receptor 1 CYSLTR1 Tclin GPCR -2.53729 368.2 209
Leukotriene B4 receptor 2 LTB4R2 Tbio GPCR -1.80085 71.0 143
Oxoeicosanoid receptor 1 OXER1 Tchem GPCR -0.73450 4.51 150