Development Level

Tclin 8 | 613
Tchem 6 | 1,598

Collection

GPCR: IDG Consortium (Complete... 1 | 25
GPCR: IDG Consortium (Targets) 1 | 126
RFA-RM-18-021 1 | 328

IMPC Phenotype

decreased basophil cell number 1 | 16
decreased circulating alanine ... 1 | 47
decreased vertical activity 1 | 208

Disease

osteosarcoma 9 | 7,950
Carcinoma 8 | 11,493
psoriasis 7 | 6,694
Asthma 6 | 385
Allergic rhinitis 5 | 94
Asthma, Aspirin-Induced 5 | 13
Cervical ripening procedure 5 | 5
Hydatidiform mole, benign 5 | 5
Incomplete miscarriage 5 | 6
Induction of labor 5 | 6
Pregnancy with abortive outcome 5 | 8
ovarian cancer 5 | 8,520
Astrocytoma, Pilocytic 4 | 3,081
Atopic dermatitis 4 | 952
Crohn's disease 4 | 321
Cancer 3 | 2,499
Endometriosis 3 | 540
Physiological Sexual Disorders 3 | 4
Sexual Dysfunction, Physiological 3 | 4
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
colon cancer 3 | 1,478
glioblastoma 3 | 5,792
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
lung cancer 3 | 4,740
lung carcinoma 3 | 2,843
Aorta Dextratransposition with Intact Ventricular Septum 2 | 2
Atherosclerosis 2 | 291
Autosomal dominant nonsyndromic deafness 17 2 | 2
Breast cancer 2 | 3,578
Coarctation of aorta 2 | 2
Common cold 2 | 67
Congenital Heart Defect Requiring Open Patent Ductus Arteriosus 2 | 2
Congenital atresia of the pulmonary valve 2 | 2
Congenital atresia of tricuspid valve 2 | 2
Drug Hypersensitivity 2 | 34
Drug allergy 2 | 36
Ebstein's anomaly of tricuspid valve 2 | 2
Impotence 2 | 42
Inflammation 2 | 120
Multiple Sclerosis 2 | 540
Ocular hypertension 2 | 42
Postpartum hemorrhage 2 | 6
Pulmonary artery stenosis 2 | 22
Rhinitis 2 | 54
Tetralogy of Fallot 2 | 63
acute myeloid leukemia 2 | 783
adrenocortical adenoma 2 | 131
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
cystic fibrosis 2 | 1,696
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
medulloblastoma, large-cell 2 | 6,241
tuberculosis 2 | 2,010
Adenocarcinoma 1 | 122
Animal Mammary Neoplasms 1 | 136
Ankylosing spondylitis 1 | 140
Arthritis, Experimental 1 | 39
Asthma, Nasal Polyps, And Aspirin Intolerance 1 | 2
Brain cancer 1 | 30
Brain infarction 1 | 22
Carcinoma, Squamous Cell 1 | 110
Chemical and Drug Induced Liver Injury 1 | 195
Cough 1 | 23
Gaucher disease type 3 1 | 67
Hemorrhagic Disorders 1 | 30
Human immunodeficiency virus infectious disease 1 | 138
Hyperalgesia 1 | 83
Infertility 1 | 188
Keshan disease 1 | 17
Liver Cirrhosis, Experimental 1 | 769
Liver diseases 1 | 87
Lymphoma 1 | 81
Malignant glioma 1 | 26
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Nasal congestion 1 | 21
Necrosis 1 | 53
Open-angle glaucoma 1 | 27
Primary pulmonary hypertension 1 | 14
Pulmonary embolism 1 | 55
Pulmonary hypertension 1 | 85
Spondylitis, Ankylosing 1 | 11
Squamous cell carcinoma 1 | 129
Stevens-Johnson syndrome 1 | 92
Trichomoniasis 1 | 10
Urticaria 1 | 67
active ulcerative colitis 1 | 764
glioblastoma multiforme 1 | 142
head and neck cancer 1 | 271
posterior fossa group A ependymoma 1 | 468
posterior fossa group B ependymoma 1 | 416
pulmonary arterial hypertension 1 | 75
severe asthma 1 | 9

Tissue

Blood and immune system 14 | 16,909
Digestive Tract 14 | 17,369
Endocrine System 14 | 18,159
Female tissues 14 | 17,400
Male tissues 14 | 17,142
Respiratory system 14 | 16,393
Skin and soft tissues 14 | 17,230
Urinary Tract 14 | 16,678
Cardiovascular System 13 | 15,192
Liver and Pancreas 13 | 16,750
Nervous System 13 | 16,725

Target Family

GPCR 14 | 408

Reactome Pathway

Eicosanoid ligand-binding rece... 14 | 14
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Prostaglandin D2 receptor 2 PTGDR2 Tchem GPCR -2.38441 265.9 439
Leukotriene B4 receptor 2 LTB4R2 Tchem GPCR -1.84108 77.0 161
Thromboxane A2 receptor TBXA2R Tclin GPCR -2.17674 123.4 112
Prostaglandin E2 receptor EP4 subtype PTGER4 Tclin GPCR -2.97753 970.7 231
Prostaglandin E2 receptor EP1 subtype PTGER1 Tclin GPCR -2.64481 402.0 168
Prostaglandin E2 receptor EP2 subtype PTGER2 Tclin GPCR -1.26196 16.4 397
Uracil nucleotide/cysteinyl leukotriene receptor GPR17 Tchem GPCR -2.19520 156.1 280
Prostaglandin D2 receptor PTGDR Tclin GPCR -2.75743 541.2 147
Cysteinyl leukotriene receptor 2 CYSLTR2 Tchem GPCR -2.01587 99.3 166
Leukotriene B4 receptor 1 LTB4R Tchem GPCR -2.74171 557.6 365