Development Level

Tbio 13 | 11,651
Tchem 12 | 1,388
Tclin 1 | 612

Collection

Kinase: IDG Consortium (Target... 1 | 125
RFA-RM-18-021 1 | 328

IMPC Phenotype

abnormal behavior 1 | 298
abnormal bone structure 1 | 187
abnormal embryo size 1 | 220
abnormal forelimb morphology 1 | 2
abnormal gait 1 | 69
abnormal locomotor activation 1 | 16
abnormal response to new envir... 1 | 10
abnormal testis morphology 1 | 43
corneal vascularization 1 | 6
decreased body length 1 | 101
decreased body weight 1 | 161
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased brain size 1 | 4
decreased circulating amylase ... 1 | 28
decreased circulating glycerol... 1 | 16
decreased circulating triglyce... 1 | 79
decreased prepulse inhibition 1 | 82
decreased vertical activity 1 | 208
embryonic growth retardation 1 | 106
embryonic lethality prior to t... 1 | 278
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased lean body mass 1 | 172
increased startle reflex 1 | 112
increased total body fat amoun... 1 | 134
limb grasping 1 | 41
male infertility 1 | 123
mammalian phenotype 1 | 17
preweaning lethality, complete... 1 | 979
preweaning lethality, incomple... 1 | 499
small epididymis 1 | 3
small heart 1 | 10
small liver 1 | 8
small lung 1 | 5
small spleen 1 | 19
small stomach 1 | 3
small testis 1 | 58
small thymus 1 | 16

Disease

Carcinoma 22 | 11,493
osteosarcoma 18 | 7,950
medulloblastoma, large-cell 15 | 6,241
lung cancer 13 | 4,740
adult high grade glioma 11 | 3,801
atypical teratoid / rhabdoid tumor 11 | 5,112
ependymoma 11 | 4,679
glioblastoma 11 | 5,792
lung carcinoma 11 | 2,843
Kidney cancer 10 | 2,613
group 3 medulloblastoma 10 | 4,104
malignant mesothelioma 10 | 3,232
psoriasis 10 | 6,694
lung adenocarcinoma 8 | 2,716
ovarian cancer 8 | 8,520
primitive neuroectodermal tumor 8 | 3,035
Astrocytoma, Pilocytic 7 | 3,081
Obesity 7 | 678
astrocytic glioma 7 | 2,597
non-small cell lung cancer 7 | 2,890
oligodendroglioma 7 | 2,850
subependymal giant cell astrocytoma 7 | 2,287
Bipolar Disorder 6 | 666
Pick disease 6 | 1,894
Rheumatoid arthritis 6 | 1,191
cystic fibrosis 6 | 1,696
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
Autosomal recessive predisposition 5 | 1,442
Breast cancer 5 | 3,578
ulcerative colitis 5 | 1,819
cutaneous lupus erythematosus 4 | 1,057
interstitial cystitis 4 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
pancreatic cancer 4 | 2,398
pituitary cancer 4 | 1,972
Autosomal dominant cerebellar ataxia 3 | 33
Hypertension 3 | 396
Nephrotic Syndrome 3 | 78
Neurodegenerative disease 3 | 414
Type 1 diabetes mellitus 3 | 109
esophageal adenocarcinoma 3 | 737
invasive ductal carcinoma 3 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
posterior fossa group B ependymoma 3 | 416
primary pancreatic ductal adenocarcinoma 3 | 1,109
Acquired metabolic disease 2 | 336
Actinic keratosis 2 | 21
Arthritis, Rheumatoid 2 | 174
Brain Hypoxia 2 | 2
Cancer 2 | 2,499
Cannabis dependence 2 | 23
Chronic obstructive pulmonary disease 2 | 184
Diabetes Mellitus, Experimental 2 | 108
Diabetes Mellitus, Insulin-Dependent 2 | 48
Diabetes Mellitus, Type 1 2 | 43
Diabetic Nephropathies 2 | 37
Diabetic Nephropathy 2 | 34
Hypertensive disease 2 | 292
Hypoxia, Brain 2 | 2
Infantile onset 2 | 238
Liver cancer 2 | 604
Myocardial Infarction 2 | 151
Osteoporosis 2 | 363
Progressive disorder 2 | 142
Proteinuria 2 | 144
Substance-Related Disorders 2 | 115
Type 2 diabetes mellitus 2 | 272
atypical teratoid/rhabdoid tumor 2 | 357
breast carcinoma 2 | 1,638
colon cancer 2 | 1,478
gastric carcinoma 2 | 807
group 4 medulloblastoma 2 | 1,855
nasopharyngeal carcinoma 2 | 1,058
primary Sjogren syndrome 2 | 735
sonic hedgehog group medulloblastoma 2 | 467
tuberculosis 2 | 2,010
Acquired immunodeficiency syndrome 1 | 197
Arthralgia 1 | 90
Autoimmune thrombocytopenia 1 | 22
Barrett's esophagus 1 | 182
Bipolar I disorder 1 | 23
Bleeding time prolonged 1 | 31
Cardiomegaly 1 | 116
Chemical and Drug Induced Liver Injury 1 | 195
Common variable immunodeficiency 1 | 101
Coronary stenosis 1 | 8
Epistaxis 1 | 43
Glanzmann's thrombasthenia 1 | 23
Hypospadias 1 | 53
Idiopathic thrombocytopenia 1 | 22
Immune thrombocytopenic purpura 1 | 24
Immunologic Deficiency Syndromes 1 | 113
Leukemia, Myelocytic, Acute 1 | 120
Lupus Erythematosus, Systemic 1 | 67
Lymphadenopathy 1 | 62
Purpura 1 | 43
Recurrent infections 1 | 48
Spinocerebellar Ataxias 1 | 34
sarcoidosis 1 | 370

Tissue

Endocrine System 26 | 18,159
Digestive Tract 25 | 17,369
Male tissues 25 | 17,142
Nervous System 25 | 16,725
Urinary Tract 25 | 16,678
Female tissues 24 | 17,400
Liver and Pancreas 24 | 16,750
Respiratory system 24 | 16,393
Skin and soft tissues 24 | 17,230
Cardiovascular System 23 | 15,192
Blood and immune system 22 | 16,909

Target Family

Enzyme 11 | 4,145
Kinase 7 | 634
Ion Channel 6 | 344
Non-IDG 2 | 12,091

Reactome Pathway

Effects of PIP2 hydrolysis 26 | 26
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Short transient receptor potential channel 3 TRPC3 Tchem Ion Channel -2.46704 294.6 217
Diacylglycerol kinase zeta DGKZ Tbio Enzyme -1.89662 90.6 157
Monoglyceride lipase MGLL Tchem Enzyme -2.48367 314.7 296
Diacylglycerol kinase gamma DGKG Tbio Enzyme -1.25727 20.7 78
Diacylglycerol kinase alpha DGKA Tbio Kinase -1.88784 80.2 264
Protein kinase C delta type PRKCD Tclin Kinase -2.18452 141.4 804
Protein kinase C eta type PRKCH Tchem Kinase -1.79158 65.4 184
Diacylglycerol kinase iota DGKI Tbio Enzyme -0.89505 7.70 152
Diacylglycerol kinase kappa DGKK Tbio Enzyme 0.00000 88
Monoacylglycerol lipase ABHD6 ABHD6 Tchem Enzyme -1.37418 26.1 71