Development Level

Tbio 30 | 11,445
Tdark 9 | 6,588
Tclin 2 | 613
Tchem 1 | 1,598

IMPC Phenotype

preweaning lethality, complete... 4 | 979
abnormal behavior 1 | 298
abnormal bone mineralization 1 | 38
abnormal lens morphology 1 | 81
abnormal maxilla morphology 1 | 17
abnormal retinal blood vessel ... 1 | 26
abnormal retinal vasculature m... 1 | 27
abnormal tooth morphology 1 | 24
cardiovascular system phenotyp... 1 | 36
cataract 1 | 92
decreased body weight 1 | 161
decreased bone mineral density 1 | 126
decreased caudal vertebrae num... 1 | 53
decreased circulating LDL chol... 1 | 38
decreased hemoglobin content 1 | 68
decreased lean body mass 1 | 135
decreased lumbar vertebrae num... 1 | 2
decreased sacral vertebrae num... 1 | 1
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
hemorrhage 1 | 23
hypoactivity 1 | 132
increased body temperature 1 | 9
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating triglyce... 1 | 42
increased hemoglobin content 1 | 45
increased lumbar vertebrae num... 1 | 1
increased sacral vertebrae num... 1 | 1
increased total body fat amoun... 1 | 134
thrombocytopenia 1 | 56
trunk curl 1 | 16

Disease

Carcinoma 23 | 11,493
ovarian cancer 21 | 8,520
lung cancer 18 | 4,740
psoriasis 16 | 6,694
Breast cancer 14 | 3,578
osteosarcoma 14 | 7,950
Cancer 12 | 2,499
lung adenocarcinoma 12 | 2,716
glioblastoma 10 | 5,792
atypical teratoid / rhabdoid tumor 9 | 5,112
group 3 medulloblastoma 9 | 4,104
invasive ductal carcinoma 9 | 2,951
Multiple myeloma 8 | 1,332
ductal carcinoma in situ 8 | 1,745
intraductal papillary-mucinous neoplasm (IPMN) 8 | 3,291
breast carcinoma 7 | 1,638
intraductal papillary-mucinous carcinoma (IPMC) 7 | 2,989
medulloblastoma, large-cell 7 | 6,241
non-small cell lung cancer 7 | 2,890
Endometriosis 6 | 540
ependymoma 6 | 4,679
malignant mesothelioma 6 | 3,232
pancreatic cancer 6 | 2,398
primitive neuroectodermal tumor 6 | 3,035
Kidney cancer 5 | 2,613
Schizophrenia 5 | 1,160
Waldenstrons macroglobulinemia 5 | 765
cystic fibrosis 5 | 1,696
group 4 medulloblastoma 5 | 1,855
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
subependymal giant cell astrocytoma 5 | 2,287
Intellectual disability 4 | 1,016
adult high grade glioma 4 | 3,801
astrocytoma 4 | 1,146
cutaneous lupus erythematosus 4 | 1,057
non-small cell lung carcinoma 4 | 317
Astrocytoma, Pilocytic 3 | 3,081
Breast Neoplasms 3 | 445
Cleft Palate 3 | 271
Connective tissue disease 3 | 62
Lupus erythematosus 3 | 57
Mammary Neoplasms 3 | 425
Rheumatoid arthritis 3 | 1,191
acute myeloid leukemia 3 | 783
colon cancer 3 | 1,478
dermatomyositis 3 | 966
diabetes mellitus 3 | 1,728
gastric carcinoma 3 | 807
nasopharyngeal carcinoma 3 | 1,058
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
pituitary cancer 3 | 1,972
primary pancreatic ductal adenocarcinoma 3 | 1,109
Adenocarcinoma of lung 2 | 142
Age related macular degeneration 2 | 72
Arthrogryposis syndrome 2 | 3
COFS syndrome 2 | 5
Carcinoma, Squamous Cell 2 | 110
Cataract 2 | 297
Cerebro-oculo-facio-skeletal syndrome 2 | 4
Cockayne Syndrome, Type 3 2 | 3
Cockayne syndrome 2 | 60
Cockayne syndrome B 2 | 2
De Sanctis-Cacchione Syndrome 2 | 2
Fibroma 2 | 18
Kleefstra syndrome 2 | 12
Lung Neoplasms 2 | 232
Mood Disorders 2 | 184
Ossifying fibroma 2 | 15
Peripheral T-cell lymphoma 2 | 25
Photosensitive trichothiodystrophy 2 | 30
Primary cutaneous T-cell lymphoma 2 | 29
Retinitis pigmentosa 20 2 | 5
Retinoblastoma 2 | 19
Squamous cell carcinoma 2 | 129
Thyroiditis 2 | 29
UV-sensitive syndrome 2 | 10
acute quadriplegic myopathy 2 | 1,158
adrenocortical carcinoma 2 | 1,428
gastric cancer 2 | 459
locked-in syndrome 2 | 14
lung carcinoma 2 | 2,843
pancreatic carcinoma 2 | 562
pediatric high grade glioma 2 | 1,064
spina bifida 2 | 1,074
Abnormal auditory evoked potential 1 | 7
Adenocarcinoma of lung (disorder) 1 | 60
Angle class 2 malocclusion 1 | 57
Chronic Obstructive Airway Disease 1 | 37
Conjunctivitis 1 | 53
Conjunctivitis, recurrent 1 | 37
Death in childhood 1 | 14
Epithelial ovarian cancer 1 | 9
Heart Diseases 1 | 43
Iron metabolism disease 1 | 20
Ovarian epithelial cancer 1 | 10
Polyploidy 1 | 4
Pulmonary Disease, Chronic Obstructive 1 | 31
Spider Veins 1 | 17
Type 1 diabetes mellitus 1 | 109
Xeroderma pigmentosum 1 | 43

Tissue

Endocrine System 41 | 18,159
Blood and immune system 40 | 16,909
Digestive Tract 40 | 17,369
Female tissues 40 | 17,400
Skin and soft tissues 40 | 17,230
Cardiovascular System 39 | 15,192
Liver and Pancreas 39 | 16,750
Male tissues 39 | 17,142
Nervous System 39 | 16,725
Respiratory system 39 | 16,393
Urinary Tract 39 | 16,678

Target Family

Non-IDG 30 | 12,091
Epigenetic 6 | 242
Transcription Factor 6 | 1,400

Reactome Pathway

ERCC6 (CSB) and EHMT2 (G9a) po... 42 | 42
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Methyl-CpG-binding domain protein 3 MBD3 Tbio Transcription Factor -0.85800 7.92 309
Histone H2B type 1-N HIST1H2BN Tbio Non-IDG -1.51422 30.2 60
Histone H2B type 1-L HIST1H2BL Tdark Non-IDG 0.35 0.40 48
Metastasis-associated protein MTA3 MTA3 Tbio Transcription Factor -1.36174 24.5 204
Chromodomain-helicase-DNA-binding protein 4 CHD4 Tbio Epigenetic -2.22229 159.7 203
Histone H2A type 1-B/E HIST1H2AB Tbio Non-IDG -1.27041 18.5 133
Chromodomain-helicase-DNA-binding protein 3 CHD3 Tbio Epigenetic -1.95633 85.2 190
Histone H2A.J H2AFJ Tdark Non-IDG -0.00172 0.83 99
Metastasis-associated protein MTA2 MTA2 Tbio Transcription Factor -1.59201 32.3 283
Histone H2A type 1-J HIST1H2AJ Tdark Non-IDG -0.13212 1.19 16