Development Level

Tbio 47 | 11,445
Tchem 5 | 1,598
Tclin 3 | 613

IMPC Phenotype

preweaning lethality, complete... 5 | 979
abnormal coat-hair pigmentatio... 2 | 64
abnormal humerus morphology 2 | 11
abnormal seminal vesicle morph... 2 | 114
abnormal tibia morphology 2 | 14
decreased body weight 2 | 161
decreased mean corpuscular hem... 2 | 31
edema 2 | 59
enlarged heart 2 | 210
improved glucose tolerance 2 | 79
increased circulating triglyce... 2 | 42
increased heart weight 2 | 62
increased or absent threshold ... 2 | 101
abnormal anxiety-related respo... 1 | 1
abnormal ear morphology 1 | 9
abnormal eye morphology 1 | 68
abnormal femur morphology 1 | 14
abnormal incisor color 1 | 3
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal pelvic girdle bone mo... 1 | 12
abnormal radius morphology 1 | 8
abnormal retina morphology 1 | 71
abnormal skin morphology 1 | 50
abnormal social-conspecific in... 1 | 3
abnormal tail morphology 1 | 25
abnormal testis morphology 1 | 43
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
cataract 1 | 92
decreased blood urea nitrogen ... 1 | 51
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating choleste... 1 | 93
decreased circulating glucose ... 1 | 126
decreased eosinophil cell numb... 1 | 24
decreased heart weight 1 | 27
decreased lean body mass 1 | 135
decreased mean corpuscular vol... 1 | 79
enlarged kidney 1 | 14
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
impaired glucose tolerance 1 | 75
impaired righting response 1 | 26
increased circulating alkaline... 1 | 122
increased circulating sodium l... 1 | 71
increased exploration in new e... 1 | 8
increased hematocrit 1 | 46
increased leukocyte cell numbe... 1 | 47
increased startle reflex 1 | 112
persistence of hyaloid vascula... 1 | 33
polycystic kidney 1 | 15
preweaning lethality, incomple... 1 | 499
prolonged PR interval 1 | 15
prolonged ST segment 1 | 36
short tibia 1 | 97
tremors 1 | 39

Disease

Carcinoma 53 | 11,493
glioblastoma 36 | 5,792
ovarian cancer 32 | 8,520
Breast cancer 29 | 3,578
pancreatic cancer 27 | 2,398
psoriasis 27 | 6,694
Kidney cancer 26 | 2,613
Astrocytoma, Pilocytic 25 | 3,081
lung carcinoma 25 | 2,843
atypical teratoid / rhabdoid tumor 24 | 5,112
osteosarcoma 24 | 7,950
ependymoma 23 | 4,679
lung cancer 22 | 4,740
malignant mesothelioma 22 | 3,232
invasive ductal carcinoma 21 | 2,951
Autosomal recessive predisposition 20 | 1,442
adult high grade glioma 20 | 3,801
ductal carcinoma in situ 18 | 1,745
medulloblastoma, large-cell 18 | 6,241
Cancer 17 | 2,499
intraductal papillary-mucinous neoplasm (IPMN) 17 | 3,291
interstitial cystitis 16 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 16 | 2,955
primary pancreatic ductal adenocarcinoma 16 | 1,109
lung adenocarcinoma 15 | 2,716
ulcerative colitis 15 | 1,819
Duchenne muscular dystrophy 14 | 601
Myopia 14 | 176
breast carcinoma 14 | 1,638
cystic fibrosis 14 | 1,696
group 3 medulloblastoma 14 | 4,104
non-small cell lung cancer 14 | 2,890
oligodendroglioma 14 | 2,850
Osteoarthritis 13 | 184
Liver cancer 12 | 604
autosomal dominant Emery-Dreifuss muscular dystrophy 12 | 510
diabetes mellitus 12 | 1,728
intraductal papillary-mucinous carcinoma (IPMC) 12 | 2,989
gastric carcinoma 11 | 807
pituitary cancer 11 | 1,972
subependymal giant cell astrocytoma 11 | 2,287
Liver Cirrhosis, Experimental 10 | 769
colon cancer 10 | 1,478
Cleft Palate 9 | 271
Muscle hypotonia 9 | 571
Schizophrenia 9 | 1,160
juvenile dermatomyositis 9 | 1,187
nasopharyngeal carcinoma 9 | 1,058
primitive neuroectodermal tumor 9 | 3,035
Atherosclerosis 8 | 291
Cataract 8 | 297
Rheumatoid arthritis 8 | 1,191
Short stature 8 | 531
acute quadriplegic myopathy 8 | 1,158
limb girdle muscular dystrophy 2A 8 | 213
medulloblastoma 8 | 720
pancreatic ductal adenocarcinoma liver metastasis 8 | 1,962
tuberculosis 8 | 2,010
Acquired scoliosis 7 | 281
Coronary artery disease 7 | 268
Curvature of spine 7 | 282
Degenerative polyarthritis 7 | 115
Knee joint valgus deformity 7 | 56
Multiple epiphyseal dysplasia 7 | 18
Platyspondyly 7 | 56
Pseudoachondroplasia 7 | 14
Skin cancer 7 | 469
adrenocortical carcinoma 7 | 1,428
astrocytic glioma 7 | 2,597
astrocytoma 7 | 1,146
cutaneous lupus erythematosus 7 | 1,057
dermatomyositis 7 | 966
Abortion, Spontaneous 6 | 109
Arthralgia 6 | 90
Atopic dermatitis 6 | 952
Becker muscular dystrophy 6 | 191
Down syndrome 6 | 499
Endometriosis 6 | 540
Gait abnormality 6 | 135
Hip Dislocation, Congenital 6 | 48
Hypersensitivity reaction type II disease 6 | 253
Hypoplastic mandible condyle 6 | 275
Intellectual disability 6 | 1,016
Joint hyperflexibility 6 | 78
Lens Opacities 6 | 231
Mandibular hypoplasia 6 | 275
Melanoma 6 | 711
Micrognathism 6 | 275
Micromelia 6 | 58
Myopathy 6 | 185
Prenatal onset 6 | 139
Prostatic Neoplasms 6 | 495
Spontaneous abortion 6 | 113
Uranostaphyloschisis 6 | 167
esophageal adenocarcinoma 6 | 737
fibroadenoma 6 | 559
non-small cell lung carcinoma 6 | 317
pediatric high grade glioma 6 | 1,064
Pick disease 5 | 1,894
sonic hedgehog group medulloblastoma 5 | 467

Tissue

Endocrine System 54 | 18,159
Digestive Tract 53 | 17,369
Female tissues 53 | 17,400
Liver and Pancreas 53 | 16,750
Skin and soft tissues 53 | 17,230
Blood and immune system 52 | 16,909
Male tissues 52 | 17,142
Nervous System 51 | 16,725
Urinary Tract 51 | 16,678
Respiratory system 50 | 16,393
Cardiovascular System 48 | 15,192

Target Family

Non-IDG 50 | 12,091
Enzyme 3 | 4,145
Kinase 1 | 634
Transcription Factor 1 | 1,400

Reactome Pathway

ECM proteoglycans 55 | 55
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Dentin sialophosphoprotein DSPP Tbio Non-IDG -2.88022 744.2 49
Integrin alpha-7 ITGA7 Tbio Non-IDG -1.63563 42.4 193
Tenascin-N TNN Tbio Non-IDG -2.01097 85.8 74
Versican core protein VCAN Tbio Non-IDG -2.88501 795.4 190
Laminin subunit gamma-1 LAMC1 Tbio Non-IDG -1.79184 56.7 318
Asporin ASPN Tbio Non-IDG -2.64447 408.2 128