Development Level

Tbio 8 | 11,445
Tchem 3 | 1,598
Tclin 1 | 613

IMPC Phenotype

abnormal bone mineralization 1 | 38
abnormal glucose homeostasis 1 | 4
decreased body weight 1 | 161
decreased circulating LDL chol... 1 | 38
decreased circulating choleste... 1 | 93
decreased circulating triglyce... 1 | 79
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating choleste... 1 | 66
increased lean body mass 1 | 172
increased total body fat amoun... 1 | 134
thrombocytosis 1 | 27

Disease

Carcinoma 9 | 11,493
ovarian cancer 8 | 8,520
glioblastoma 7 | 5,792
osteosarcoma 7 | 7,950
Cancer 6 | 2,499
ependymoma 6 | 4,679
lung cancer 6 | 4,740
Breast cancer 5 | 3,578
atypical teratoid / rhabdoid tumor 5 | 5,112
medulloblastoma, large-cell 5 | 6,241
Bipolar Disorder 4 | 666
Breast Neoplasms 4 | 445
Mammary Neoplasms 4 | 425
interstitial cystitis 4 | 2,312
nasopharyngeal carcinoma 4 | 1,058
pancreatic cancer 4 | 2,398
ulcerative colitis 4 | 1,819
Astrocytoma, Pilocytic 3 | 3,081
Autosomal recessive predisposition 3 | 1,442
Epilepsy 3 | 792
Kidney cancer 3 | 2,613
Lung Neoplasms 3 | 232
Seizures 3 | 596
acute myeloid leukemia 3 | 783
adult high grade glioma 3 | 3,801
astrocytic glioma 3 | 2,597
fibroadenoma 3 | 559
group 3 medulloblastoma 3 | 4,104
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,955
invasive ductal carcinoma 3 | 2,951
lung adenocarcinoma 3 | 2,716
pituitary cancer 3 | 1,972
progressive supranuclear palsy 3 | 676
subependymal giant cell astrocytoma 3 | 2,287
Adenoma 2 | 167
Alzheimer's disease 2 | 658
Anemia 2 | 365
Disease Progression 2 | 136
Gallbladder Neoplasms 2 | 10
HER2-positive carcinoma of breast 2 | 21
Heart disease 2 | 306
Hypoplastic mandible condyle 2 | 275
Lipodystrophy 2 | 40
Major Depressive Disorder 2 | 301
Mandibular hypoplasia 2 | 275
Mental Depression 2 | 333
Micrognathism 2 | 275
Myofibrillar myopathy 1 2 | 6
Myofibrillar myopathy 3 2 | 5
Neoplasm Metastasis 2 | 168
Neuropathy 2 | 261
Obesity, Abdominal 2 | 24
Osteoporosis 2 | 363
Pick's disease 2 | 15
Polycystic ovary syndrome 2 | 360
Prostatic Neoplasms 2 | 495
Recurrence 2 | 33
Schizophrenia 2 | 1,160
Unipolar Depression 2 | 250
colon cancer 2 | 1,478
cystic fibrosis 2 | 1,696
diabetes mellitus 2 | 1,728
ductal carcinoma in situ 2 | 1,745
gallbladder neoplasm 2 | 10
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung carcinoma 2 | 2,843
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
primary pancreatic ductal adenocarcinoma 2 | 1,109
spina bifida 2 | 1,074
Acanthosis Nigricans 1 | 27
Acne 1 | 52
Breast disease 1 | 7
Breast fibroadenoma 1 | 8
Bronchioloalveolar Adenocarcinoma 1 | 14
Carcinogenesis 1 | 8
Carcinoma, Ductal, Breast 1 | 11
Cell Transformation, Neoplastic 1 | 97
Conversion disorder 1 | 6
Edema 1 | 81
Exanthem 1 | 37
Gastric Cancer, Hereditary Diffuse 1 | 12
Glioma Susceptibility 1 1 | 5
Gynecomastia 1 | 64
Hypertriglyceridemia result 1 | 37
Lobular neoplasia 1 | 15
Lymphatic Metastasis 1 | 15
Marijuana Abuse 1 | 31
Menorrhagia 1 | 25
Mitral regurgitation, mild 1 | 32
Neoplasm of stomach 1 | 11
Neoplasms, Experimental 1 | 40
Neoplastic Cell Transformation 1 | 89
Non-small cell lung cancer, positive for epidermal growth factor receptor expression 1 | 4
Pain 1 | 103
Steatohepatitis 1 | 44
Stomach Carcinoma 1 | 11
Stomach cancer 1 | 30
Stomatitis 1 | 21
Type 1 diabetes mellitus 1 | 109

Tissue

Blood and immune system 12 | 16,909
Cardiovascular System 12 | 15,192
Digestive Tract 12 | 17,369
Endocrine System 12 | 18,159
Female tissues 12 | 17,400
Liver and Pancreas 12 | 16,750
Male tissues 12 | 17,142
Nervous System 12 | 16,725
Respiratory system 12 | 16,393
Skin and soft tissues 12 | 17,230
Urinary Tract 12 | 16,678

Target Family

Non-IDG 6 | 12,091
Kinase 4 | 634
Enzyme 2 | 4,145

Reactome Pathway

Downregulation of ERBB2:ERBB3 ... 12 | 12
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Polyubiquitin-B UBB Tbio Non-IDG -1.98860 97.4 427
Polyubiquitin-C UBC Tbio Non-IDG -2.90157 61.9 143
Ubiquitin-60S ribosomal protein L40 UBA52 Tbio Non-IDG -2.12534 131.4 181
Ubiquitin-40S ribosomal protein S27a RPS27A Tbio Non-IDG -1.66231 61.9 139
Pro-neuregulin-2, membrane-bound isoform NRG2 Tbio Non-IDG -1.46980 32.0 141
Receptor tyrosine-protein kinase erbB-2 ERBB2 Tclin Kinase -4.28550 20244.6 3859
Ubiquitin carboxyl-terminal hydrolase 8 USP8 Tbio Enzyme -1.72968 58.3 209
E3 ubiquitin-protein ligase NRDP1 RNF41 Tbio Enzyme -1.58988 45.0 148
Receptor tyrosine-protein kinase erbB-3 ERBB3 Tchem Kinase -2.97833 870.3 1652
Pro-neuregulin-1, membrane-bound isoform NRG1 Tbio Non-IDG -2.93105 922.4 560