Development Level

Tbio 18 | 11,445
Tdark 2 | 6,588
Tchem 1 | 1,598
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, incomple... 2 | 499
abnormal behavioral response t... 1 | 66
abnormal gait 1 | 69
abnormal optic disc morphology 1 | 10
abnormal retinal blood vessel ... 1 | 26
abnormal testis morphology 1 | 43
convulsive seizures 1 | 13
decreased body length 1 | 101
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
head bobbing 1 | 5
increased erythrocyte cell num... 1 | 39
increased prepulse inhibition 1 | 32
increased total body fat amoun... 1 | 134
preweaning lethality, complete... 1 | 979
small testis 1 | 58

Disease

medulloblastoma, large-cell 18 | 6,241
Astrocytoma, Pilocytic 17 | 3,081
glioblastoma 17 | 5,792
adult high grade glioma 16 | 3,801
atypical teratoid / rhabdoid tumor 16 | 5,112
ependymoma 16 | 4,679
astrocytic glioma 15 | 2,597
oligodendroglioma 15 | 2,850
Carcinoma 13 | 11,493
primitive neuroectodermal tumor 13 | 3,035
group 3 medulloblastoma 12 | 4,104
Pick disease 11 | 1,894
Schizophrenia 10 | 1,160
psoriasis 10 | 6,694
subependymal giant cell astrocytoma 10 | 2,287
lung cancer 9 | 4,740
lung carcinoma 8 | 2,843
malignant mesothelioma 8 | 3,232
osteosarcoma 8 | 7,950
ovarian cancer 8 | 8,520
non-small cell lung cancer 7 | 2,890
Bipolar Disorder 6 | 666
Breast cancer 5 | 3,578
Cognitive delay 5 | 608
Epilepsy 5 | 792
Global developmental delay 5 | 608
Kidney cancer 5 | 2,613
Mental and motor retardation 5 | 608
Parkinson's disease 5 | 392
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
pituitary cancer 5 | 1,972
Depressive disorder 4 | 409
Mental Depression 4 | 333
Seizures 4 | 596
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,291
invasive ductal carcinoma 4 | 2,951
Attention deficit hyperactivity disorder 3 | 278
Blepharoptosis 3 | 231
Botulism 3 | 24
Generalized hypotonia 3 | 37
Intellectual disability 3 | 1,016
Neurodevelopmental Disorders 3 | 70
Tetanus 3 | 68
active ulcerative colitis 3 | 764
colon cancer 3 | 1,478
cystic fibrosis 3 | 1,696
group 4 medulloblastoma 3 | 1,855
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
lung adenocarcinoma 3 | 2,716
pancreatic cancer 3 | 2,398
Absent speech 2 | 43
Acquired metabolic disease 2 | 336
Alzheimer's disease 2 | 658
Animal Mammary Neoplasms 2 | 136
Autistic Disorder 2 | 364
Axial hypotonia 2 | 46
Broad flat nasal bridge 2 | 236
Cataract 7 2 | 32
Cerebellar Ataxia 2 | 304
Cerebral atrophy 2 | 178
Cleft Palate 2 | 271
Congenital Epicanthus 2 | 177
Dysarthria 2 | 192
Early infantile epileptic encephalopathy with suppression bursts 2 | 10
Gaucher disease type 1 2 | 180
Global developmental delay, severe 2 | 47
Hypoplastic mandible condyle 2 | 275
Low Vision 2 | 174
Mammary Neoplasms, Animal 2 | 136
Mammary Neoplasms, Experimental 2 | 154
Mandibular hypoplasia 2 | 275
Micrognathism 2 | 275
Multiple myeloma 2 | 1,332
Muscle Weakness 2 | 170
Nasal bridge wide 2 | 236
Nystagmus 2 | 317
Obesity 2 | 678
Orbital separation excessive 2 | 244
Psychotic Disorders 2 | 151
Reduced fetal movement 2 | 51
Rheumatoid arthritis 2 | 1,191
Severe mental retardation (I.Q. 20-34) 2 | 99
Severe psychomotor retardation 2 | 47
Short stature 2 | 531
Small head 2 | 374
Strabismus 2 | 270
Toxic encephalopathy 2 | 141
Tremor 2 | 113
Visual Impairment 2 | 174
X-linked dominant 2 | 57
active Crohn's disease 2 | 922
aldosterone-producing adenoma 2 | 665
astrocytoma 2 | 1,146
ductal carcinoma in situ 2 | 1,745
medulloblastoma 2 | 720
nasopharyngeal carcinoma 2 | 1,058
nonverbal 2 | 43
pancreatic carcinoma 2 | 562
tuberculosis 2 | 2,010

Tissue

Digestive Tract 21 | 17,369
Endocrine System 21 | 18,159
Female tissues 21 | 17,400
Liver and Pancreas 21 | 16,750
Male tissues 21 | 17,142
Nervous System 21 | 16,725
Respiratory system 21 | 16,393
Skin and soft tissues 21 | 17,230
Urinary Tract 21 | 16,678
Blood and immune system 20 | 16,909
Cardiovascular System 19 | 15,192

Target Family

Non-IDG 19 | 12,091
Enzyme 1 | 4,145
Kinase 1 | 634
Transporter 1 | 473

Reactome Pathway

Dopamine Neurotransmitter Rele... 22 | 22
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Synapsin-1 SYN1 Tbio Non-IDG -2.86836 712.4 770
Peripheral plasma membrane protein CASK CASK Tchem Kinase -2.12241 130.2 227
Synapsin-3 SYN3 Tbio Non-IDG -1.99912 100.6 110
Synapsin-2 SYN2 Tbio Non-IDG 0.00000 0
Peripheral-type benzodiazepine receptor-associated protein 1 TSPOAP1 Tbio Non-IDG -0.53932 4.30 18
Vesicle-associated membrane protein 2 VAMP2 Tbio Non-IDG -2.53335 323.7 203
Regulating synaptic membrane exocytosis protein 1 RIMS1 Tbio Non-IDG -1.95711 85.7 11
Protein lin-7 homolog C LIN7C Tbio Non-IDG -1.01220 10.6 110
Liprin-alpha-3 PPFIA3 Tdark Non-IDG -1.44046 26.8 42
Syntaxin-binding protein 1 STXBP1 Tbio Non-IDG -2.30714 221.0 351