Development Level

Tchem 13 | 1,890
Tbio 10 | 10,625
Tclin 1 | 602

IMPC Phenotype

abnormal cornea morphology 1 | 24
abnormal skin condition 1 | 6
decreased body weight 1 | 174
decreased circulating amylase ... 1 | 24
decreased circulating sodium l... 1 | 18
decreased lean body mass 1 | 195
decreased mean corpuscular hem... 1 | 19
decreased mean corpuscular vol... 1 | 50
decreased thermal nociceptive ... 1 | 4
increased CD4-positive, alpha ... 1 | 15
increased body weight 1 | 42
increased circulating alkaline... 1 | 119
increased circulating free fat... 1 | 17
increased leukocyte cell numbe... 1 | 37
increased thermal nociceptive ... 1 | 9

Disease

Cancer 14 | 2,346
glioblastoma 13 | 5,572
lung cancer 13 | 4,473
ovarian cancer 13 | 8,491
tuberculosis 13 | 1,563
lung carcinoma 11 | 2,844
psoriasis 11 | 6,685
osteosarcoma 10 | 7,933
subependymal giant cell astrocytoma 9 | 2,287
cutaneous lupus erythematosus 8 | 1,056
pilocytic astrocytoma 8 | 3,086
ulcerative colitis 8 | 2,087
Asthma 7 | 349
IGA Glomerulonephritis 7 | 454
diabetes mellitus 7 | 1,663
malignant mesothelioma 7 | 3,163
pediatric high grade glioma 7 | 2,712
Arthritis 6 | 248
Inflammatory bowel disease 6 | 142
Reperfusion Injury 6 | 84
Rheumatoid Arthritis 6 | 1,170
astrocytoma 6 | 1,493
cystic fibrosis 6 | 1,670
interstitial cystitis 6 | 2,299
medulloblastoma, large-cell 6 | 6,234
Breast cancer 5 | 3,098
Influenza 5 | 142
Malaria 5 | 140
Pneumonia 5 | 133
Prostatic Neoplasms 5 | 471
group 4 medulloblastoma 5 | 1,875
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,289
juvenile dermatomyositis 5 | 1,189
non-small cell lung cancer 5 | 2,798
Hypersensitivity reaction type II disease 4 | 235
Mantle cell lymphoma 4 | 20
Meningitis 4 | 46
Obesity 4 | 616
adrenocortical carcinoma 4 | 1,427
colon cancer 4 | 1,475
gastric carcinoma 4 | 832
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
invasive ductal carcinoma 4 | 2,950
lung adenocarcinoma 4 | 2,714
pancreatic cancer 4 | 2,300
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,795
Atherosclerosis 3 | 275
Brain Ischemia 3 | 87
Carcinoma 3 | 2,147
Colorectal Neoplasms 3 | 217
Heat Stroke 3 | 12
Herpes Simplex Encephalitis, Susceptibility To, 1 3 | 5
Inflammation 3 | 109
Keratitis 3 | 42
Liver disease 3 | 219
Lung disease 3 | 136
Melioidosis 3 | 11
Multiple Sclerosis 3 | 498
Multiple myeloma 3 | 1,327
Neoplasm Invasiveness 3 | 127
Neoplastic Cell Transformation 3 | 81
Perinatal necrotizing enterocolitis 3 | 18
Peritonitis 3 | 37
adult high grade glioma 3 | 2,148
aldosterone-producing adenoma 3 | 664
dermatomyositis 3 | 966
ependymoma 3 | 2,514
mucosa-associated lymphoid tissue lymphoma 3 | 480
oligodendroglioma 3 | 2,849
pancreatic carcinoma 3 | 567
periodontitis 3 | 269
pituitary cancer 3 | 1,972
Allergic hypersensitivity disease 2 | 123
Chronic obstructive pulmonary disease 2 | 147
Colonic Neoplasms 2 | 126
Common variable immunodeficiency 2 | 98
Coronary artery disease 2 | 240
Dermatitis 2 | 141
Diabetes Mellitus, Non-Insulin-Dependent 2 | 161
Duchenne muscular dystrophy 2 | 602
Heart disease 2 | 279
Hypertensive disease 2 | 193
Invasive Pneumococcal Disease, Recurrent Isolated, 1 2 | 2
Kidney disease 2 | 397
Leishmaniasis 2 | 49
Leptospirosis 2 | 17
Lung Neoplasms 2 | 171
MYCOBACTERIUM TUBERCULOSIS, SUSCEPTIBILITY TO (finding) 2 | 12
Mammary Neoplasms 2 | 410
Mastitis 2 | 48
Myocardial Ischemia 2 | 169
Neoplasm Metastasis 2 | 138
Non-alcoholic Fatty Liver Disease 2 | 40
active Crohn's disease 2 | 918
breast carcinoma 2 | 1,614
chronic lymphosyte leukemia 2 | 232
fibroadenoma 2 | 557
hepatocellular carcinoma 2 | 550
urothelial carcinoma 2 | 318

Tissue

Blood and immune system 24 | 17,994
Cardiovascular System 24 | 17,957
Digestive Tract 24 | 18,472
Endocrine System 24 | 18,511
Female tissues 24 | 18,646
Liver and Pancreas 24 | 18,135
Male tissues 24 | 17,968
Nervous System 24 | 18,560
Respiratory system 24 | 17,483
Urinary Tract 24 | 18,443
Skin and soft tissues 23 | 18,114

Target Family

Non-IDG 16 | 11,969
Kinase 5 | 634
Transcription Factor 3 | 1,400

Reactome Pathway

Diseases of Immune System 24 | 24
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lymphocyte antigen 96 LY96 Tbio Non-IDG -2.73333 490.7 314
Toll-like receptor 10 TLR10 Tbio Non-IDG -1.75724 56.1 295
Nuclear factor NF-kappa-B p100 subunit NFKB2 Tchem Transcription Factor -2.25781 180.0 594
NF-kappa-B inhibitor beta NFKBIB Tbio Non-IDG -2.13078 112.5 524
Toll-like receptor 2 TLR2 Tchem Non-IDG -3.47133 3173.5 946
TNF receptor-associated factor 3 TRAF3 Tbio Non-IDG -2.48370 297.6 330
Toll-like receptor 5 TLR5 Tchem Non-IDG -2.75432 581.0 635
NF-kappa-B inhibitor alpha NFKBIA Tchem Non-IDG -3.34592 1960.9 1181
Toll-like receptor 3 TLR3 Tchem Non-IDG -3.04822 1147.2 751
Tyrosine-protein kinase BTK BTK Tclin Kinase -3.02467 1061.8 721