Development Level

Tbio 12 | 11,445
Tchem 10 | 1,598

IMPC Phenotype

abnormal cecum morphology 1 | 7
abnormal cornea morphology 1 | 31
abnormal skin condition 1 | 6
abnormal vibrissa morphology 1 | 25
decreased circulating amylase ... 1 | 28
decreased circulating sodium l... 1 | 22
decreased heart weight 1 | 27
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 31
decreased mean corpuscular vol... 1 | 79
decreased thermal nociceptive ... 1 | 2
enlarged cecum 1 | 5
enlarged uterus 1 | 11
increased circulating alkaline... 1 | 122
increased circulating free fat... 1 | 20
increased eosinophil cell numb... 1 | 11
increased leukocyte cell numbe... 1 | 47
increased mean corpuscular vol... 1 | 92
increased neutrophil cell numb... 1 | 46
increased thermal nociceptive ... 1 | 9
preweaning lethality, incomple... 1 | 499
small superior vagus ganglion 1 | 74

Disease

Carcinoma 16 | 11,493
Cancer 14 | 2,499
glioblastoma 14 | 5,792
ovarian cancer 13 | 8,520
tuberculosis 13 | 2,010
lung cancer 12 | 4,740
lung carcinoma 10 | 2,843
psoriasis 10 | 6,694
adult high grade glioma 9 | 3,801
Asthma 8 | 385
Astrocytoma, Pilocytic 8 | 3,081
diabetes mellitus 8 | 1,728
osteosarcoma 8 | 7,950
subependymal giant cell astrocytoma 8 | 2,287
Immunologic Deficiency Syndromes 7 | 113
Pneumonia 7 | 174
Schizophrenia 7 | 1,160
cutaneous lupus erythematosus 7 | 1,057
malignant mesothelioma 7 | 3,232
Arthritis 6 | 290
Breast cancer 6 | 3,578
Inflammatory bowel disease 6 | 151
Reperfusion Injury 6 | 86
Rheumatoid arthritis 6 | 1,191
astrocytoma 6 | 1,146
cystic fibrosis 6 | 1,696
medulloblastoma, large-cell 6 | 6,241
ulcerative colitis 6 | 1,819
Hypertension 5 | 396
Influenza 5 | 142
Liver Cirrhosis, Experimental 5 | 769
Malaria 5 | 160
Prostatic Neoplasms 5 | 495
ependymoma 5 | 4,679
group 4 medulloblastoma 5 | 1,855
interstitial cystitis 5 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 5 | 3,291
juvenile dermatomyositis 5 | 1,187
Allergic hypersensitivity disease 4 | 126
Autosomal recessive predisposition 4 | 1,442
Brain Injuries 4 | 65
Eosinophilia 4 | 28
Hypersensitivity reaction type II disease 4 | 253
Hypertensive disease 4 | 292
Keratitis 4 | 62
Meningitis 4 | 67
Obesity 4 | 678
adrenocortical carcinoma 4 | 1,428
colon cancer 4 | 1,478
gastric carcinoma 4 | 807
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,989
invasive ductal carcinoma 4 | 2,951
lung adenocarcinoma 4 | 2,716
non-small cell lung cancer 4 | 2,890
pancreatic cancer 4 | 2,398
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Atherosclerosis 3 | 291
Brain Ischemia 3 | 110
Cell Transformation, Neoplastic 3 | 97
Cerebrovascular disease 3 | 238
Cholestasis 3 | 155
Cholestasis, Extrahepatic 3 | 25
Colorectal Neoplasms 3 | 243
Coronary artery disease 3 | 268
Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere 3 | 5
HERPES SIMPLEX ENCEPHALITIS, SUSCEPTIBILITY TO, 1 3 | 5
Heat Stroke 3 | 13
Herpes encephalitis 3 | 6
Inflammation 3 | 120
Kidney cancer 3 | 2,613
Kidney disease 3 | 430
Liver disease 3 | 237
Lung disease 3 | 142
Mantle cell lymphoma 3 | 23
Melioidosis 3 | 17
Multiple Sclerosis 3 | 540
Multiple myeloma 3 | 1,332
Neoplasm Invasiveness 3 | 161
Neoplastic Cell Transformation 3 | 89
Perinatal necrotizing enterocolitis 3 | 21
Peritonitis 3 | 43
Salmonellosis 3 | 42
aldosterone-producing adenoma 3 | 665
atypical teratoid / rhabdoid tumor 3 | 5,112
dermatomyositis 3 | 966
mucosa-associated lymphoid tissue lymphoma 3 | 484
oligodendroglioma 3 | 2,850
pancreatic carcinoma 3 | 562
periodontitis 3 | 293
pituitary cancer 3 | 1,972
Colonic Neoplasms 2 | 142
Diarrhea 2 | 253
Hepatic enzyme increased 2 | 81
Liver Dysfunction 2 | 99
Liver enzymes abnormal 2 | 81
Liver function test increased 2 | 81
Liver function tests abnormal finding 2 | 81
Subclinical abnormal liver function tests 2 | 81
Transaminases increased 2 | 81

Tissue

Blood and immune system 22 | 16,909
Cardiovascular System 22 | 15,192
Digestive Tract 22 | 17,369
Endocrine System 22 | 18,159
Female tissues 22 | 17,400
Liver and Pancreas 22 | 16,750
Male tissues 22 | 17,142
Nervous System 22 | 16,725
Respiratory system 22 | 16,393
Skin and soft tissues 22 | 17,230
Urinary Tract 22 | 16,678

Target Family

Non-IDG 15 | 12,091
Kinase 4 | 634
Transcription Factor 3 | 1,400

Reactome Pathway

Diseases of Immune System 22 | 22
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lymphocyte antigen 96 LY96 Tchem Non-IDG -2.77678 541.2 369
Toll-like receptor 6 TLR6 Tbio Non-IDG -2.18033 129.1 692
Platelet glycoprotein 4 CD36 Tbio Non-IDG -2.63884 376.0 1155
Nuclear factor NF-kappa-B p100 subunit NFKB2 Tchem Transcription Factor -2.29577 191.3 637
Myeloid differentiation primary response protein MyD88 MYD88 Tbio Non-IDG -3.26747 1795.4 672
NF-kappa-B essential modulator IKBKG Tbio Kinase -3.07452 1188.4 879
Interleukin-1 receptor-associated kinase 4 IRAK4 Tchem Kinase -2.28820 202.2 610
Toll-like receptor 10 TLR10 Tbio Non-IDG -1.80961 63.7 288
Inhibitor of nuclear factor kappa-B kinase subunit alpha CHUK Tchem Kinase -2.36360 203.6 1101
TIR domain-containing adapter molecule 1 TICAM1 Tbio Non-IDG -1.50467 33.0 226