Development Level

Tbio 10 | 11,651
Tdark 1 | 6,593

IMPC Phenotype

abnormal behavior 1 | 298
abnormal epididymis morphology 1 | 42
abnormal heart morphology 1 | 162
abnormal lens morphology 1 | 81
abnormal locomotor behavior 1 | 24
abnormal retina morphology 1 | 71
abnormal seminal vesicle morph... 1 | 114
abnormal testis morphology 1 | 43
cataract 1 | 92
decreased mean platelet volume 1 | 25
enlarged epididymis 1 | 31
enlarged heart 1 | 210
hypoactivity 1 | 132
preweaning lethality, incomple... 1 | 499
small testis 1 | 58

Disease

Carcinoma 6 | 11,493
ovarian cancer 6 | 8,520
psoriasis 6 | 6,694
medulloblastoma, large-cell 5 | 6,241
ulcerative colitis 4 | 1,819
Autosomal recessive predisposition 3 | 1,442
Ethylmalonic encephalopathy 3 | 12
cystic fibrosis 3 | 1,696
ductal carcinoma in situ 3 | 1,745
group 3 medulloblastoma 3 | 4,104
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 3 | 3,291
invasive ductal carcinoma 3 | 2,951
oligodendroglioma 3 | 2,850
osteosarcoma 3 | 7,950
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,962
tuberculosis 3 | 2,010
Astrocytoma, Pilocytic 2 | 3,081
Atherosclerosis 2 | 291
Breast cancer 2 | 3,578
Cerebellar Ataxia 2 | 304
Cognitive delay 2 | 608
Epilepsy 2 | 792
Global developmental delay 2 | 608
Liver Cirrhosis, Experimental 2 | 769
Melanoma 2 | 711
Mental and motor retardation 2 | 608
Pick disease 2 | 1,894
Seizures 2 | 596
adrenocortical carcinoma 2 | 1,428
atypical teratoid/rhabdoid tumor 2 | 357
colon cancer 2 | 1,478
glioblastoma 2 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
lung cancer 2 | 4,740
malignant mesothelioma 2 | 3,232
pituitary cancer 2 | 1,972
Abnormality of the retinal vasculature 1 | 59
Acidosis, Lactic 1 | 97
Animal Mammary Neoplasms 1 | 136
Argininosuccinic aciduria 1 | 17
Brain disease 1 | 96
Carcinoma, Hepatocellular 1 | 228
Cardiovascular system disease 1 | 246
Colitis 1 | 54
Common variable immunodeficiency 1 | 101
Coronary artery disease 1 | 268
Cystathioninuria 1 | 2
Death in early childhood 1 | 82
Death in infancy 1 | 82
Dental caries 1 | 164
Developmental regression 1 | 95
Diarrhea 1 | 253
Encephalopathies 1 | 43
Extrapyramidal Disorders 1 | 29
Extrapyramidal sign 1 | 29
Failure to gain weight 1 | 365
Fatty liver disease 1 | 103
Fine hair 1 | 42
Glycine encephalopathy 1 | 29
Homocystinuria 1 | 21
Hyperhomocysteinemia 1 | 37
Hypermethioninemia 1 | 11
Hypertension 1 | 396
Kidney disease 1 | 430
Lactic acidemia 1 | 95
Late tooth eruption 1 | 61
Leigh disease 1 | 100
Lens subluxation 1 | 12
Lipid metabolism disorder 1 | 114
Liver carcinoma 1 | 240
Long QT syndrome 1 | 39
Loss of developmental milestones 1 | 95
MYELODYSPLASTIC SYNDROME 1 | 53
Mammary Neoplasms, Animal 1 | 136
Mammary Neoplasms, Experimental 1 | 154
Mastitis 1 | 48
Mental deterioration in childhood 1 | 95
Methylmalonic acidemia 1 | 37
Microcephaly 1 | 166
Muscle Hypertonia 1 | 88
Neurodegenerative disease 1 | 414
Neurodevelopmental regression 1 | 95
Pediatric failure to thrive 1 | 365
Perinatal necrotizing enterocolitis 1 | 21
Psychomotor regression 1 | 95
Psychomotor regression beginning in infancy 1 | 95
Psychomotor regression in infants 1 | 95
Psychomotor regression, progressive 1 | 95
Pulmonary edema 1 | 17
Pyruvate decarboxylase deficiency 1 | 16
Retinal Neovascularization 1 | 4
Serine deficiency 1 | 9
Spinal Dysraphism 1 | 12
Toxic shock syndrome 1 | 28
Vitiligo 1 | 73
X-linked cerebral adrenoleukodystrophy 1 | 116
interstitial lung disease 1 | 298
tuberculosis and treatment for 3 months 1 | 179

Tissue

Blood and immune system 11 | 16,909
Cardiovascular System 11 | 15,192
Digestive Tract 11 | 17,369
Endocrine System 11 | 18,159
Female tissues 11 | 17,400
Liver and Pancreas 11 | 16,750
Male tissues 11 | 17,142
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Skin and soft tissues 11 | 17,230
Urinary Tract 11 | 16,678

Target Family

Enzyme 9 | 4,145
Non-IDG 1 | 12,091
Transporter 1 | 473

Reactome Pathway

Degradation of cysteine and ho... 11 | 11
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Thioredoxin, mitochondrial TXN2 Tbio Non-IDG -2.05954 125.2 260
Sulfite oxidase, mitochondrial SUOX Tbio Enzyme -2.03377 111.1 244
Cysteine dioxygenase type 1 CDO1 Tbio Enzyme -1.58332 35.3 90
Mitochondrial dicarboxylate carrier SLC25A10 Tbio Transporter -1.25522 17.2 72
Aspartate aminotransferase, mitochondrial GOT2 Tbio Enzyme -3.23630 1435.0 450
Thiosulfate:glutathione sulfurtransferase TSTD1 Tdark Enzyme 0.23 1.22 11
3-mercaptopyruvate sulfurtransferase MPST Tbio Enzyme -1.85628 72.4 79
Cysteine sulfinic acid decarboxylase CSAD Tbio Enzyme -2.16604 143.8 134
Persulfide dioxygenase ETHE1, mitochondrial ETHE1 Tbio Enzyme -1.85699 73.4 147
Thiosulfate sulfurtransferase TST Tbio Enzyme -2.35239 208.6 79