Development Level

Tdark 17 | 6,588
Tbio 15 | 11,445
Tchem 6 | 1,598

IMPC Phenotype

abnormal vibrissa morphology 1 | 25
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased heart rate 1 | 18
increased mean corpuscular vol... 1 | 92
preweaning lethality, incomple... 1 | 499
prolonged RR interval 1 | 8

Disease

diabetes mellitus 11 | 1,728
Carcinoma 9 | 11,493
psoriasis 7 | 6,694
lung cancer 6 | 4,740
ovarian cancer 6 | 8,520
ulcerative colitis 6 | 1,819
glioblastoma 5 | 5,792
osteosarcoma 5 | 7,950
Breast cancer 4 | 3,578
Cancer 4 | 2,499
Pneumonia 4 | 174
cutaneous lupus erythematosus 4 | 1,057
cystic fibrosis 4 | 1,696
lung carcinoma 4 | 2,843
tuberculosis 4 | 2,010
Arthritis 3 | 290
Astrocytoma, Pilocytic 3 | 3,081
Bipolar Disorder 3 | 666
Colitis, Ulcerative 3 | 59
Inflammatory bowel disease 3 | 151
Otitis Media 3 | 52
Rheumatoid arthritis 3 | 1,191
Tonsillitis 3 | 16
active Crohn's disease 3 | 922
active ulcerative colitis 3 | 764
adult high grade glioma 3 | 3,801
interstitial cystitis 3 | 2,312
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,989
invasive ductal carcinoma 3 | 2,951
medulloblastoma, large-cell 3 | 6,241
pancreatic cancer 3 | 2,398
periodontitis 3 | 293
subependymal giant cell astrocytoma 3 | 2,287
Acne 2 | 52
Adverse reaction to drug 2 | 61
Arthritis, Rheumatoid 2 | 174
Asthma 2 | 385
Atherosclerosis 2 | 291
Atrioventricular Septal Defect 2 | 22
Bacterial vaginosis 2 | 15
Brain Injuries 2 | 65
Candidiasis 2 | 55
Clostridium difficile colitis 2 | 12
Common cold 2 | 67
Congenital diaphragmatic hernia 2 | 67
Coronary artery disease 2 | 268
Crohn's disease 2 | 321
Dermatitis 2 | 157
Drug-Related Side Effects and Adverse Reactions 2 | 62
Human immunodeficiency virus infectious disease 2 | 138
Hypersensitivity 2 | 63
Hypersensitivity reaction type II disease 2 | 253
Inflammatory Bowel Diseases 2 | 35
Keratitis 2 | 62
Kidney disease 2 | 430
Leprosy 2 | 73
Liver disease 2 | 237
Lung disease 2 | 142
Lyme disease 2 | 26
Mastitis 2 | 48
Obesity 2 | 678
Prevention of Thromboembolism with Chronic Atrial Fibrillation 2 | 5
Prevention of deep vein thrombosis 2 | 7
Pulmonary Fibrosis 2 | 106
Waldenstrons macroglobulinemia 2 | 765
astrocytic glioma 2 | 2,597
breast carcinoma 2 | 1,638
ependymoma 2 | 4,679
hepatocellular carcinoma 2 | 547
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
malignant mesothelioma 2 | 3,232
mucosa-associated lymphoid tissue lymphoma 2 | 484
primary pancreatic ductal adenocarcinoma 2 | 1,109
sarcoidosis 2 | 370
urothelial carcinoma 2 | 318
ventricular septal defect 2 | 20
Acquired immunodeficiency syndrome 1 | 197
Acute Promyelocytic Leukemia 1 | 40
Age related macular degeneration 1 | 72
Carcinoma of colon 1 | 32
Celiac disease 1 | 116
Deglutition Disorders 1 | 132
Dental caries 1 | 164
Dyspnea 1 | 76
Eosinophilia 1 | 28
Filariasis 1 | 21
Leptospirosis 1 | 18
Leukemia, Promyelocytic, Acute 1 | 36
Lytic lesion 1 | 32
Meningitis 1 | 67
Pancreatitis 1 | 123
Perinatal necrotizing enterocolitis 1 | 21
Rotting teeth 1 | 73
Skin Ulcer 1 | 48
Telangiectasia of the skin 1 | 39
Vitiligo 1 | 73
chronic kidney disease 1 | 90
hypopigmented skin patch 1 | 59
pulmonary tuberculosis 1 | 9

Tissue

Male tissues 34 | 17,142
Endocrine System 22 | 18,159
Skin and soft tissues 18 | 17,230
Digestive Tract 17 | 17,369
Female tissues 16 | 17,400
Blood and immune system 14 | 16,909
Liver and Pancreas 13 | 16,750
Urinary Tract 12 | 16,678
Nervous System 11 | 16,725
Respiratory system 11 | 16,393
Cardiovascular System 8 | 15,192

Target Family

Non-IDG 34 | 12,091
Enzyme 2 | 4,145
GPCR 2 | 408

Reactome Pathway

Defensins 38 | 38
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Beta-defensin 118 DEFB118 Tbio Non-IDG -0.54407 3.50 7
Beta-defensin 126 DEFB126 Tbio Non-IDG -1.32124 21.5 11
Beta-defensin 133 DEFB133 Tdark Non-IDG 0.00000 4
Beta-defensin 135 DEFB135 Tdark Non-IDG 0.78 0.14 3
Beta-defensin 136 DEFB136 Tdark Non-IDG 0.00000 5
Putative beta-defensin 109B DEFB109B Tdark Non-IDG 0.00000 0
Beta-defensin 112 DEFB112 Tdark Non-IDG -0.45230 3.00 53
Beta-defensin 110 DEFB110 Tdark Non-IDG 0.34 0.34 7
Beta-defensin 114 DEFB114 Tbio Non-IDG -0.60687 3.71 6
Beta-defensin 113 DEFB113 Tdark Non-IDG 0.12 0.42 3