Development Level

Tbio 2 | 11,445

Disease

Adenocarcinoma of lung 2 | 142
Adenocarcinoma of lung (disorder) 2 | 60
Cancer 2 | 2,499
Carcinoma 2 | 11,493
Endometrial Neoplasms 2 | 55
Endometrial cancer 2 | 311
Endometrial carcinoma 2 | 15
Lynch syndrome 2 | 35
Microsatellite Instability 2 | 12
group 3 medulloblastoma 2 | 4,104
Abdominal Pain 1 | 98
Abnormality of the abdomen 1 | 14
Adenoma 1 | 167
Adenomatous Polyposis Coli 1 | 16
Anxiety 1 | 136
Anxiety disease 1 | 113
Attention deficit hyperactivity disorder 1 | 278
Autosomal recessive predisposition 1 | 1,442
Axillary freckling 1 | 5
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1 1 | 13
Basal cell carcinoma 1 | 54
Basal cell nevi 1 | 23
Birthmark 1 | 35
Breast cancer 1 | 3,578
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5 1 | 1
Cafe-au-Lait Spots 1 | 37
Chronic obstructive pulmonary disease 1 | 184
Colorectal Neoplasms, Hereditary Nonpolyposis 1 | 9
Colorectal cancer 1 | 25
Constipation 1 | 181
DOID:2627 1 | 94
Death in early adulthood 1 | 24
Death in early childhood 1 | 82
Death in infancy 1 | 82
Depressive disorder 1 | 409
Down syndrome 1 | 499
Dyschezia 1 | 135
Epilepsy 1 | 792
Familial adenomatous polyposis 1 | 32
Fatigue 1 | 182
Fibrous skin tumor of tuberous sclerosis 1 | 18
Gastric leiomyoma 1 | 3
Gastrointestinal Hemorrhage 1 | 52
Hematologic Neoplasms 1 | 22
Hereditary Nonpolyposis Colorectal Cancer 1 | 11
Hereditary Nonpolyposis Colorectal Neoplasms 1 | 8
Hereditary nonpolyposis colorectal carcinoma 1 | 18
Hyperpigmented macules 1 | 42
Increased gastric cancer 1 | 21
Intermittent migraine headaches 1 | 68
Intracranial hypertension 1 | 32
Irritation - emotion 1 | 68
Kidney cancer 1 | 2,613
Leukemia 1 | 104
Lymphoma 1 | 81
Lynch Syndrome 1 1 | 4
Malabsorption 1 | 82
Malignant tumor of colon 1 | 19
Migraine Disorders 1 | 76
Muir-Torre syndrome 1 | 4
Multiple myeloma 1 | 1,332
Muscle Hypertonia 1 | 88
Muscle hypotonia 1 | 571
Nausea and vomiting 1 | 97
Neuroblastoma 1 | 80
Prostatic Neoplasms 1 | 495
Rectal Neoplasms 1 | 18
Rhabdomyosarcoma 1 | 39
Sebaceous adenoma 1 | 26
Seizures 1 | 596
Stomach Neoplasms 1 | 300
Torre-Muir syndrome 1 | 3
Tumor Predisposition Syndrome 1 | 6
Turcot syndrome 1 | 5
Turcot syndrome (disorder) 1 | 5
Waldenstrons macroglobulinemia 1 | 765
Weight decreased 1 | 103
atypical teratoid / rhabdoid tumor 1 | 5,112
dermatomyositis 1 | 966
ependymoma 1 | 4,679
glioblastoma 1 | 5,792
intraductal papillary-mucinous adenoma (IPMA) 1 | 2,955
invasive ductal carcinoma 1 | 2,951
juvenile dermatomyositis 1 | 1,187
lung adenocarcinoma 1 | 2,716
lung cancer 1 | 4,740
medulloblastoma 1 | 720
medulloblastoma, large-cell 1 | 6,241
nasopharyngeal carcinoma 1 | 1,058
non-small cell lung cancer 1 | 2,890
osteosarcoma 1 | 7,950
ovarian cancer 1 | 8,520
pediatric high grade glioma 1 | 1,064
primitive neuroectodermal tumor 1 | 3,035
psoriasis 1 | 6,694
subependymal giant cell astrocytoma 1 | 2,287

Tissue

Blood and immune system 2 | 16,909
Cardiovascular System 2 | 15,192
Digestive Tract 2 | 17,369
Endocrine System 2 | 18,159
Female tissues 2 | 17,400
Liver and Pancreas 2 | 16,750
Male tissues 2 | 17,142
Nervous System 2 | 16,725
Respiratory system 2 | 16,393
Skin and soft tissues 2 | 17,230
Urinary Tract 2 | 16,678

Target Family

Epigenetic 1 | 242
Non-IDG 1 | 12,091

Reactome Pathway

Defective Mismatch Repair Asso... 2 | 2
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
DNA mismatch repair protein Msh6 MSH6 Tbio Epigenetic -2.72594 572.3 479
DNA mismatch repair protein Msh3 MSH3 Tbio Non-IDG -2.44872 276.2 202