Development Level

Tbio 6 | 11,445

IMPC Phenotype

increased lean body mass 1 | 172

Disease

Carcinoma 6 | 11,493
Astrocytoma, Pilocytic 4 | 3,081
colon cancer 4 | 1,478
ependymoma 4 | 4,679
glioblastoma 4 | 5,792
invasive ductal carcinoma 4 | 2,951
lung cancer 4 | 4,740
ovarian cancer 4 | 8,520
pituitary cancer 4 | 1,972
psoriasis 4 | 6,694
Atherosclerosis 3 | 291
Duchenne muscular dystrophy 3 | 601
Pick disease 3 | 1,894
adult high grade glioma 3 | 3,801
atypical teratoid / rhabdoid tumor 3 | 5,112
breast carcinoma 3 | 1,638
diabetes mellitus 3 | 1,728
ductal carcinoma in situ 3 | 1,745
limb girdle muscular dystrophy 2A 3 | 213
lung adenocarcinoma 3 | 2,716
malignant mesothelioma 3 | 3,232
oligodendroglioma 3 | 2,850
osteosarcoma 3 | 7,950
pancreatic cancer 3 | 2,398
ulcerative colitis 3 | 1,819
Breast cancer 2 | 3,578
Cancer 2 | 2,499
Degenerative disc disease 2 | 35
Down syndrome 2 | 499
Ehlers-Danlos syndrome 2 | 43
Melanoma 2 | 711
Myopia 2 | 176
Osteoarthritis 2 | 184
Rheumatoid arthritis 2 | 1,191
Schizophrenia 2 | 1,160
adrenocortical carcinoma 2 | 1,428
aldosterone-producing adenoma 2 | 665
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 510
cutaneous lupus erythematosus 2 | 1,057
cystic fibrosis 2 | 1,696
esophageal adenocarcinoma 2 | 737
gastric carcinoma 2 | 807
group 3 medulloblastoma 2 | 4,104
interstitial cystitis 2 | 2,312
intraductal papillary-mucinous adenoma (IPMA) 2 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 2 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung carcinoma 2 | 2,843
medulloblastoma, large-cell 2 | 6,241
non-small cell lung cancer 2 | 2,890
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,962
pterygium 2 | 76
sonic hedgehog group medulloblastoma 2 | 467
Abnormal vision 1 | 52
Aortic aneurysm 1 | 38
Brachydactyly 1 | 156
Cardiovascular system disease 1 | 246
Chondrodysplasia punctata 1 | 41
Chorioretinal atrophy 1 | 11
Corneal disease 1 | 31
Coxa valga 1 | 22
Coxa valga deformity 1 | 22
Decreased projection of maxilla 1 | 66
Decreased visual acuity, progressive 1 | 36
Deficiency of upper jaw bones 1 | 66
Dengue disease 1 | 23
Dentinogenesis imperfecta 1 | 25
Endometrial Neoplasms 1 | 55
Fatty liver disease 1 | 103
Fibrosis 1 | 44
Gaucher disease type 1 1 | 180
Gonorrhea 1 | 13
Hyperkyphosis 1 | 111
Hypoplasia of the maxilla 1 | 66
Hypoplastic feet 1 | 66
Hypotrophic maxilla 1 | 66
Kabuki syndrome 1 | 27
Kyphosis deformity of spine 1 | 114
Large intestine cancer 1 | 126
Leiomyoma 1 | 32
Limited elbow extension 1 | 19
Maxillary retrognathia 1 | 66
Muscular dystrophy 1 | 75
Pneumonia 1 | 174
Progressive visual loss 1 | 36
Retinal Detachment 1 | 51
Retrusion of upper jaw bones 1 | 66
Salivary Gland Neoplasms 1 | 46
Short-trunked dwarfism 1 | 13
Urinary Bladder Neoplasms 1 | 114
Vitreoretinal degeneration 1 | 9
X- linked recessive 1 | 110
X-linked cerebral adrenoleukodystrophy 1 | 116
Yellow fever 1 | 16
chronic kidney disease 1 | 90
facioscapulohumeral dystrophy 1 | 288
fascioscapulohumeral muscular dystrophy 1 | 100
head and neck cancer and chronic obstructive pulmonary disease 1 | 239
interstitial lung disease 1 | 298
posterior fossa group A ependymoma 1 | 468

Tissue

Endocrine System 6 | 18,159
Nervous System 6 | 16,725
Blood and immune system 5 | 16,909
Cardiovascular System 5 | 15,192
Digestive Tract 5 | 17,369
Female tissues 5 | 17,400
Liver and Pancreas 5 | 16,750
Male tissues 5 | 17,142
Respiratory system 5 | 16,393
Skin and soft tissues 5 | 17,230
Urinary Tract 5 | 16,678

Target Family

Non-IDG 6 | 12,091

Reactome Pathway

Defective CHST3 causes SEDCJD 6 | 6
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Versican core protein VCAN Tbio Non-IDG -2.88501 795.4 190
Chondroitin sulfate proteoglycan 5 CSPG5 Tbio Non-IDG -2.55925 360.8 181
Chondroitin sulfate proteoglycan 4 CSPG4 Tbio Non-IDG -2.20166 186.1 395
Neurocan core protein NCAN Tbio Non-IDG -2.19768 158.4 127
Decorin DCN Tbio Non-IDG -3.05208 1155.4 480
Biglycan BGN Tbio Non-IDG -2.73039 529.9 267