Development Level

Tbio 19 | 10,625
Tchem 5 | 1,890
Tdark 3 | 7,003
Tclin 2 | 602

IMPC Term

abnormal bone mineralization 1 | 55
decreased B cell number 1 | 30
decreased body weight 1 | 174
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 41
decreased circulating choleste... 1 | 85
decreased circulating free fat... 1 | 39
decreased circulating triglyce... 1 | 83
decreased mature B cell number 1 | 25
increased IgG1 level 1 | 1
increased T cell number 1 | 15
increased exploration in new e... 1 | 56
preweaning lethality, complete... 1 | 633
preweaning lethality, incomple... 1 | 260

Disease

psoriasis 15 | 6,685
ovarian cancer 12 | 8,484
intraductal papillary-mucinous neoplasm (IPMN) 11 | 3,289
lung adenocarcinoma 11 | 2,713
lung cancer 11 | 4,466
osteosarcoma 11 | 7,933
pancreatic cancer 11 | 2,300
Cancer 10 | 2,346
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,988
ulcerative colitis 10 | 2,087
lung carcinoma 9 | 2,844
Breast cancer 8 | 3,094
interstitial cystitis 8 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,956
Carcinoma 7 | 2,147
cystic fibrosis 7 | 1,665
medulloblastoma, large-cell 7 | 6,234
nasopharyngeal carcinoma 7 | 1,056
non-small cell lung cancer 7 | 2,798
esophageal adenocarcinoma 6 | 737
glioblastoma 5 | 5,572
invasive ductal carcinoma 5 | 2,950
primary Sjogren syndrome 5 | 789
Adenoma 4 | 165
Asthma 4 | 349
Biliary papillomatosis 4 | 4
Otitis media 4 | 32
active Crohn's disease 4 | 918
breast carcinoma 4 | 1,614
colon cancer 4 | 1,475
dermatomyositis 4 | 933
diabetes mellitus 4 | 1,663
group 3 medulloblastoma 4 | 2,254
mucosa-associated lymphoid tissue lymphoma 4 | 480
pilocytic astrocytoma 4 | 3,086
subependymal giant cell astrocytoma 4 | 2,287
Gastritis 3 | 44
Lupus erythematosus 3 | 80
Multiple myeloma 3 | 1,327
Stomach Neoplasms 3 | 282
Waldenstrons macroglobulinemia 3 | 765
active ulcerative colitis 3 | 477
adult high grade glioma 3 | 2,148
astrocytoma 3 | 1,493
chronic lymphosyte leukemia 3 | 232
gastric carcinoma 3 | 832
head and neck cancer and chronic obstructive pulmonary disease 3 | 237
interstitial lung disease 3 | 291
malignant mesothelioma 3 | 3,162
non primary Sjogren syndrome sicca 3 | 840
pediatric high grade glioma 3 | 2,712
spina bifida 3 | 1,064
tuberculosis 3 | 1,557
urothelial carcinoma 3 | 318
Allergic hypersensitivity disease 2 | 123
Allergic rhinitis 2 | 91
Alzheimer's disease 2 | 644
Atopic dermatitis 2 | 944
Blastic phase chronic myeloid leukemia 2 | 58
Bronchitis 2 | 44
Cherubism 2 | 14
Chronic Myelocytic Leukemia Accelerated Phase 2 | 59
Chronic obstructive pulmonary disease 2 | 146
Common cold 2 | 63
Common wart 2 | 5
Down syndrome 2 | 548
Dry eye syndrome 2 | 13
Endometrial cancer 2 | 25
Gastrointestinal system disease 2 | 50
Kidney cancer 2 | 118
Lung diseases 2 | 48
Melanoma 2 | 261
Mesothelioma 2 | 40
Multiple Sclerosis 2 | 498
Pneumonia 2 | 133
Sinusitis 2 | 30
Systemic scleroderma 2 | 66
cutaneous lupus erythematosus 2 | 1,056
ductal carcinoma in situ 2 | 1,745
juvenile dermatomyositis 2 | 1,189
non-small cell lung carcinoma 2 | 413
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
periodontitis 2 | 269
pituitary cancer 2 | 1,972
posterior fossa group A ependymoma 2 | 1,511
tuberculosis and treatment for 6 months 2 | 686
Chronic Lymphocytic Leukemia 1 | 242
Colitis 1 | 46
Drug allergy 1 | 36
Hypersensitivity 1 | 63
Liver cancer 1 | 31
Peripheral T-cell lymphoma 1 | 24
Proteinuria 1 | 63
Thyrotoxicosis 1 | 38
Urticaria 1 | 53
atypical teratoid/rhabdoid tumor 1 | 1,095
cystic fibrosis and chronic rhinosinusitis 1 | 213
facioscapulohumeral dystrophy 1 | 286
pulmonary arterial hypertension 1 | 36
tuberculosis and treatment for 3 months 1 | 327

Tissue

Cardiovascular System 27 | 17,958
Digestive Tract 27 | 18,473
Respiratory system 27 | 17,484
Urinary Tract 27 | 18,444
Blood and immune system 26 | 17,995
Endocrine System 26 | 18,512
Female tissues 26 | 18,647
Liver and Pancreas 26 | 18,136
Nervous System 26 | 18,561
Skin and soft tissues 26 | 18,115
Male tissues 25 | 17,969

Target Family

Non-IDG 25 | 11,971
Kinase 3 | 634
Enzyme 1 | 4,146

Reactome Pathway

Dectin-2 family 29 | 29
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Mucin-1 MUC1 Tbio Non-IDG -3.49560 3532.0 1851
Mucin-3B MUC3B Tdark Non-IDG -0.48407 3.54 0
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 PLCG2 Tchem Enzyme -2.37849 233.2 634
Mucin-16 MUC16 Tchem Non-IDG -2.01137 120.3 0
C-type lectin domain family 4 member D CLEC4D Tbio Non-IDG -1.33503 21.4 153
C-type lectin domain family 10 member A CLEC10A Tbio Non-IDG -1.98972 104.6 184
Mucin-2 MUC2 Tbio Non-IDG -2.85699 723.7 0
Mucin-5AC MUC5AC Tchem Non-IDG -2.96111 932.0 284
C-type lectin domain family 4 member C CLEC4C Tbio Non-IDG -1.88719 77.5 100
Mucin-5B MUC5B Tbio Non-IDG -3.17792 1495.3 128