Development Level

Tbio 7 | 10,625
Tchem 1 | 1,890
Tdark 1 | 7,003

IMPC Phenotype

abnormal QRS complex 1 | 25
abnormal sleep behavior 1 | 63
convulsive seizures 1 | 11
decreased threshold for audito... 1 | 32
increased body length 1 | 20
increased fasted circulating g... 1 | 68

Disease

glioblastoma 7 | 5,572
ovarian cancer 7 | 8,491
pediatric high grade glioma 7 | 2,712
pilocytic astrocytoma 6 | 3,086
Breast cancer 5 | 3,098
atypical teratoid / rhabdoid tumor 5 | 4,369
interstitial cystitis 5 | 2,299
malignant mesothelioma 5 | 3,163
posterior fossa group A ependymoma 5 | 1,511
primitive neuroectodermal tumor 5 | 3,031
Duchenne muscular dystrophy 4 | 602
medulloblastoma, large-cell 4 | 6,234
non-small cell lung cancer 4 | 2,798
osteosarcoma 4 | 7,933
pancreatic cancer 4 | 2,300
ulcerative colitis 4 | 2,087
cystic fibrosis 3 | 1,670
gastric carcinoma 3 | 832
group 3 medulloblastoma 3 | 2,254
intraductal papillary-mucinous adenoma (IPMA) 3 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 3 | 2,988
juvenile dermatomyositis 3 | 1,189
lung carcinoma 3 | 2,844
primary pancreatic ductal adenocarcinoma 3 | 1,271
psoriasis 3 | 6,685
Biliary cirrhosis 2 | 33
Bladder Neoplasm 2 | 109
Cancer 2 | 2,346
Cutis laxa 2 | 28
Hepatitis B 2 | 103
Hepatitis C 2 | 90
Hepatolenticular Degeneration 2 | 24
Iris disease 2 | 9
Irregular astigmatism 2 | 11
Osteogenesis imperfecta 2 | 34
Polycystic Ovary Syndrome 2 | 334
active Crohn's disease 2 | 918
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,289
limb girdle muscular dystrophy 2A 2 | 156
lung adenocarcinoma 2 | 2,714
lung cancer 2 | 4,473
sonic hedgehog group medulloblastoma 2 | 1,482
Acquired metabolic disease 1 | 267
Allergic hypersensitivity disease 1 | 123
Allergic rhinitis 1 | 92
Aortic aneurysm 1 | 34
Aortic valve insufficiency 1 | 22
Arthritis 1 | 248
Atherosclerosis 1 | 275
Atopic dermatitis 1 | 944
Atrial heart septal defect 1 | 15
Attention deficit hyperactivity disorder 1 | 156
Autosomal recessive non-syndromic intellectual disability 1 | 8
Becker muscular dystrophy 1 | 187
Carcinoma 1 | 2,147
Cardiovascular system disease 1 | 194
Cataract 1 | 104
Cleft palate 1 | 125
Cutis Laxa, Autosomal Recessive, Type 1A 1 | 3
Cutis Laxa, Autosomal Recessive, Type I 1 | 3
Dentinogenesis imperfecta 1 | 24
Ellis-Van Creveld syndrome 1 | 19
Exfoliation syndrome 1 | 8
Familial thoracic aortic aneurysm and aortic dissection 1 | 13
Gaucher disease type 3 1 | 76
Glaucoma 1 | 135
Keratoconus 1 | 49
Mammary Neoplasms 1 | 410
Menkes disease 1 | 20
Neoplasm Invasiveness 1 | 127
Neoplastic Cell Transformation 1 | 81
Oral Submucous Fibrosis 1 | 18
Osteogenesis imperfecta type III (disorder) 1 | 11
Ostium secundum atrial septal defect 1 | 8
Pulmonary hypertension 1 | 52
Squamous cell carcinoma of esophagus 1 | 82
Trichorhinophalangeal syndrome type II 1 | 14
Umbilical hernia 1 | 18
Vernal conjunctivitis 1 | 2
adrenocortical carcinoma 1 | 1,427
astrocytic glioma 1 | 2,241
atypical teratoid/rhabdoid tumor 1 | 1,095
autosomal dominant Emery-Dreifuss muscular dystrophy 1 | 499
breast carcinoma 1 | 1,614
cystic fibrosis and chronic rhinosinusitis 1 | 213
diabetes mellitus 1 | 1,663
esophageal adenocarcinoma 1 | 737
fascioscapulohumeral muscular dystrophy 1 | 100
head and neck cancer 1 | 270
interstitial lung disease 1 | 292
medulloblastoma 1 | 1,524
mucosa-associated lymphoid tissue lymphoma 1 | 480
non-small cell lung carcinoma 1 | 413
oligodendroglioma 1 | 2,849
osteogenesis imperfecta type 3 1 | 11
pancreatic ductal adenocarcinoma liver metastasis 1 | 1,795
pituitary cancer 1 | 1,972
post-traumatic stress disorder 1 | 45
tuberculosis 1 | 1,563
urothelial carcinoma 1 | 318

Tissue

Blood and immune system 9 | 17,994
Cardiovascular System 9 | 17,957
Digestive Tract 9 | 18,472
Endocrine System 9 | 18,511
Female tissues 9 | 18,646
Liver and Pancreas 9 | 18,135
Male tissues 9 | 17,968
Nervous System 9 | 18,560
Respiratory system 9 | 17,483
Skin and soft tissues 9 | 18,114
Urinary Tract 9 | 18,443

Target Family

Enzyme 6 | 4,146
Non-IDG 3 | 11,969

Reactome Pathway

Crosslinking of collagen fibri... 9 | 9
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Lysyl oxidase homolog 4 LOXL4 Tbio Enzyme -1.32760 22.2 124
Lysyl oxidase homolog 3 LOXL3 Tbio Enzyme -1.18771 14.5 89
Procollagen C-endopeptidase enhancer 1 PCOLCE Tbio Enzyme -1.70526 50.9 128
Tolloid-like protein 1 TLL1 Tbio Non-IDG -1.40917 23.4 60
Bone morphogenetic protein 1 BMP1 Tchem Non-IDG -2.34268 220.1 155
Lysyl oxidase homolog 1 LOXL1 Tbio Enzyme -2.53721 344.5 145
Lysyl oxidase homolog 2 LOXL2 Tbio Enzyme -2.17984 142.0 237
Protein-lysine 6-oxidase LOX Tbio Enzyme -3.33078 2063.0 465
Tolloid-like protein 2 TLL2 Tdark Non-IDG -0.95989 5.61 29