Development Level

Tbio 31 | 10,625
Tdark 7 | 7,003
Tchem 4 | 1,890

Collection

Eligible Kinase Proteins 1 | 134

IMPC Term

preweaning lethality, complete... 2 | 633
preweaning lethality, incomple... 2 | 260
abnormal behavior 1 | 226
abnormal spleen morphology 1 | 36
decreased bone mineral content 1 | 157
decreased fasted circulating g... 1 | 49
decreased lean body mass 1 | 195
decreased respiratory quotient 1 | 12
decreased startle reflex 1 | 48
hyperactivity 1 | 108
impaired righting response 1 | 19
increased blood urea nitrogen ... 1 | 44
increased circulating creatini... 1 | 29
increased total body fat amoun... 1 | 57
small kidney 1 | 10
small superior vagus ganglion 1 | 20

Disease

glioblastoma 21 | 5,572
medulloblastoma, large-cell 21 | 6,234
ovarian cancer 21 | 8,484
osteosarcoma 17 | 7,933
lung cancer 14 | 4,466
psoriasis 14 | 6,685
pilocytic astrocytoma 13 | 3,086
atypical teratoid / rhabdoid tumor 12 | 4,369
group 3 medulloblastoma 11 | 2,254
lung carcinoma 11 | 2,844
Breast cancer 10 | 3,094
non-small cell lung cancer 10 | 2,798
pediatric high grade glioma 10 | 2,712
primitive neuroectodermal tumor 10 | 3,031
subependymal giant cell astrocytoma 10 | 2,287
Multiple myeloma 9 | 1,327
invasive ductal carcinoma 9 | 2,950
Pick disease 8 | 1,893
posterior fossa group A ependymoma 8 | 1,511
astrocytic glioma 7 | 2,241
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
lung adenocarcinoma 7 | 2,713
malignant mesothelioma 7 | 3,162
oligodendroglioma 7 | 2,849
Waldenstrons macroglobulinemia 6 | 765
breast carcinoma 6 | 1,614
dermatomyositis 6 | 933
ependymoma 6 | 2,514
active Crohn's disease 5 | 918
acute quadriplegic myopathy 5 | 1,157
astrocytoma 5 | 1,493
colon cancer 5 | 1,475
ductal carcinoma in situ 5 | 1,745
intraductal papillary-mucinous carcinoma (IPMC) 5 | 2,988
Duchenne muscular dystrophy 4 | 602
Rheumatoid Arthritis 4 | 1,160
adult high grade glioma 4 | 2,148
atypical teratoid/rhabdoid tumor 4 | 1,095
diabetes mellitus 4 | 1,663
group 4 medulloblastoma 4 | 1,875
interstitial cystitis 4 | 2,299
intraductal papillary-mucinous adenoma (IPMA) 4 | 2,956
juvenile dermatomyositis 4 | 1,189
pancreatic cancer 4 | 2,300
pituitary cancer 4 | 1,972
ulcerative colitis 4 | 2,087
HIV Infections 3 | 100
Intellectual disability 3 | 573
Night Blindness 3 | 39
Skin Neoplasms 3 | 49
Squamous cell carcinoma 3 | 94
cystic fibrosis 3 | 1,665
medulloblastoma 3 | 1,524
non primary Sjogren syndrome sicca 3 | 840
posterior fossa group B ependymoma 3 | 1,530
primary pancreatic ductal adenocarcinoma 3 | 1,271
sonic hedgehog group medulloblastoma 3 | 1,482
Adult T-Cell Lymphoma/Leukemia 2 | 30
Amnesia 2 | 17
Bradyopsia 2 | 10
Congenital stationary night blindness 2 | 27
Diabetes Mellitus, Non-Insulin-Dependent 2 | 157
IGA Glomerulonephritis 2 | 454
Mammary Neoplasms 2 | 410
Neuropathy 2 | 210
Obesity 2 | 616
Parkinson's disease 2 | 364
Peripheral Neuropathy 2 | 303
Prostatic Neoplasms 2 | 471
Schizophrenia 2 | 501
Substance Withdrawal Syndrome 2 | 52
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
cutaneous lupus erythematosus 2 | 1,056
non-inflammatory breast cancer 2 | 208
primary Sjogren syndrome 2 | 789
sarcoidosis 2 | 358
Acquired metabolic disease 1 | 267
Animal Mammary Neoplasms 1 | 136
Blindness 1 | 84
Cataract 1 | 104
Colorectal Neoplasms 1 | 217
Depressive disorder 1 | 48
Gaucher disease type 1 1 | 171
Huntington's disease 1 | 72
Liver diseases 1 | 66
Lymphoma 1 | 56
Major Depressive Disorder 1 | 106
Mammary Neoplasms, Experimental 1 | 150
Muscle Weakness 1 | 92
Muscular dystrophy 1 | 48
Myopia 1 | 99
Neurodegenerative disease 1 | 383
Osteoporosis 1 | 257
Retinal Degeneration 1 | 49
Retinitis pigmentosa 1 | 153
Weight Gain 1 | 87
active ulcerative colitis 1 | 477
facioscapulohumeral dystrophy 1 | 286
hereditary spastic paraplegia 1 | 313
severe Alzheimer's disease 1 | 49

Tissue

Blood and immune system 42 | 17,995
Digestive Tract 42 | 18,473
Endocrine System 42 | 18,512
Female tissues 42 | 18,647
Liver and Pancreas 42 | 18,136
Male tissues 42 | 17,969
Nervous System 42 | 18,561
Skin and soft tissues 42 | 18,115
Urinary Tract 42 | 18,444
Cardiovascular System 41 | 17,958
Respiratory system 40 | 17,484

Target Family

Non-IDG 39 | 11,971
Kinase 3 | 634

Reactome Pathway

Cooperation of PDCL (PhLP1) an... 42 | 42
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
T-complex protein 1 subunit delta CCT4 Tbio Non-IDG -1.76354 56.6 151
T-complex protein 1 subunit theta CCT8 Tbio Non-IDG -1.45966 29.4 180
T-complex protein 1 subunit epsilon CCT5 Tbio Non-IDG -1.39059 24.5 183
Regulator of G-protein signaling 7 RGS7 Tbio Non-IDG -1.66114 49.5 132
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 GNB2 Tbio Non-IDG -0.43889 2.98 102
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 GNB1 Tbio Non-IDG -1.15715 18.1 144
Guanine nucleotide-binding protein G(i) subunit alpha-2 GNAI2 Tbio Non-IDG -1.23038 16.6 188
T-complex protein 1 subunit gamma CCT3 Tbio Non-IDG -2.17641 143.4 144
T-complex protein 1 subunit alpha TCP1 Tbio Non-IDG -2.24508 169.4 383
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 GNG8 Tdark Non-IDG -2.14544 154.5 32