Development Level

Tdark 57 | 7,003
Tbio 42 | 10,625
Tchem 5 | 1,890
Tclin 2 | 602

IMPC Term

increased circulating sodium l... 2 | 71
abnormal locomotor activation 1 | 26
cardiovascular system phenotyp... 1 | 35
decreased circulating glucose ... 1 | 121
decreased heart rate variabili... 1 | 11
decreased prepulse inhibition 1 | 52
increased aggression 1 | 2
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
shortened RR interval 1 | 19
thrombocytopenia 1 | 46

Disease

lung cancer 28 | 4,466
non-small cell lung cancer 25 | 2,798
ovarian cancer 25 | 8,484
ulcerative colitis 25 | 2,087
psoriasis 24 | 6,685
lung adenocarcinoma 23 | 2,713
lung carcinoma 23 | 2,844
interstitial cystitis 21 | 2,299
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,795
osteosarcoma 19 | 7,933
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
tuberculosis 17 | 1,557
invasive ductal carcinoma 16 | 2,950
glioblastoma 14 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
malignant mesothelioma 14 | 3,162
pancreatic cancer 14 | 2,300
Complement deficiency 13 | 15
adrenocortical carcinoma 13 | 1,427
periodontitis 13 | 269
pilocytic astrocytoma 13 | 3,086
chronic lymphosyte leukemia 12 | 232
subependymal giant cell astrocytoma 12 | 2,287
Age related macular degeneration 10 | 84
Cancer 10 | 2,346
Kidney disease 10 | 396
colon cancer 10 | 1,475
medulloblastoma, large-cell 10 | 6,234
Duchenne muscular dystrophy 9 | 602
Immunologic Deficiency Syndromes 9 | 16
dermatomyositis 9 | 933
mucosa-associated lymphoid tissue lymphoma 9 | 480
primary Sjogren syndrome 9 | 789
Anemia 8 | 252
Breast cancer 8 | 3,094
Multiple myeloma 8 | 1,327
Rheumatoid Arthritis 8 | 1,160
Vascular disease 8 | 281
acute quadriplegic myopathy 8 | 1,157
astrocytoma 8 | 1,493
cutaneous lupus erythematosus 8 | 1,056
juvenile dermatomyositis 8 | 1,189
limb girdle muscular dystrophy 2A 8 | 156
primary pancreatic ductal adenocarcinoma 8 | 1,271
IGA Glomerulonephritis 7 | 454
cystic fibrosis 7 | 1,665
esophageal adenocarcinoma 7 | 737
hemolytic-uremic syndrome 7 | 28
pituitary cancer 7 | 1,972
posterior fossa group A ependymoma 7 | 1,511
systemic lupus erythematosus 7 | 156
Atopic dermatitis 6 | 944
Atypical Hemolytic Uremic Syndrome 6 | 9
Becker muscular dystrophy 6 | 187
Carcinoma 6 | 2,147
Lupus erythematosus 6 | 80
Macular degeneration 6 | 41
Meningitis 6 | 46
Progressive relapsing multiple sclerosis 6 | 18
breast carcinoma 6 | 1,614
diabetes mellitus 6 | 1,663
gastric carcinoma 6 | 832
pediatric high grade glioma 6 | 2,712
sonic hedgehog group medulloblastoma 6 | 1,482
Amebiasis 5 | 22
Down syndrome 5 | 548
Leukemia 5 | 88
Lupus Erythematosus, Systemic 5 | 73
Lymphoma 5 | 56
Thrombocytopenia 5 | 105
atypical teratoid / rhabdoid tumor 5 | 4,369
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
cystic fibrosis and chronic rhinosinusitis 5 | 213
group 3 medulloblastoma 5 | 2,254
group 4 medulloblastoma 5 | 1,875
head and neck cancer and chronic obstructive pulmonary disease 5 | 237
nasopharyngeal carcinoma 5 | 1,056
oligodendroglioma 5 | 2,849
3MC syndrome 4 | 4
Chronic obstructive pulmonary disease 4 | 146
Type 1 diabetes mellitus 4 | 101
active Crohn's disease 4 | 918
aldosterone-producing adenoma 4 | 664
chronic kidney disease 4 | 90
ductal carcinoma in situ 4 | 1,745
interstitial lung disease 4 | 291
Arthritis 3 | 248
Atherosclerosis 3 | 275
Endometriosis 3 | 535
Juvenile arthritis 3 | 124
Malaria 3 | 140
Multiple Sclerosis 3 | 498
adult high grade glioma 3 | 2,148
astrocytic glioma 3 | 2,241
chronic rhinosinusitis 3 | 512
fibroadenoma 3 | 557
hepatocellular carcinoma 3 | 532
nephrosclerosis 3 | 329
pancreatic carcinoma 3 | 567

Tissue

Blood and immune system 91 | 17,995
Digestive Tract 91 | 18,473
Female tissues 91 | 18,647
Respiratory system 91 | 17,484
Skin and soft tissues 91 | 18,115
Liver and Pancreas 90 | 18,136
Urinary Tract 90 | 18,444
Cardiovascular System 88 | 17,958
Endocrine System 87 | 18,512
Nervous System 87 | 18,561
Male tissues 84 | 17,969

Target Family

Non-IDG 98 | 11,971
Enzyme 4 | 4,146
GPCR 3 | 406
Transcription Factor 1 | 1,400

Reactome Pathway

Complement cascade 106 | 106
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Complement component C9 C9 Tbio Non-IDG -1.85517 71.0 229
Complement C1q subcomponent subunit C C1QC Tbio Non-IDG -1.27032 17.5 141
Complement C1q subcomponent subunit B C1QB Tbio Non-IDG -1.63026 41.3 161
Complement C1q subcomponent subunit A C1QA Tbio Non-IDG -1.71898 50.3 208
Ig lambda-7 chain C region IGLC7 Tdark Non-IDG 228.7 0
CD59 glycoprotein CD59 Tbio Non-IDG -3.23780 1768.6 739
Immunoglobulin lambda variable 1-44 IGLV1-44 Tdark Non-IDG 0.00000 0
Immunoglobulin heavy variable 1-2 IGHV1-2 Tdark Non-IDG 0.00000 0