Development Level

Tdark 57 | 7,003
Tbio 42 | 10,625
Tchem 5 | 1,890
Tclin 2 | 602

IMPC Phenotype

increased circulating sodium l... 2 | 71
abnormal locomotor activation 1 | 26
cardiovascular system phenotyp... 1 | 35
decreased circulating glucose ... 1 | 121
decreased heart rate variabili... 1 | 11
decreased prepulse inhibition 1 | 52
increased aggression 1 | 2
increased erythrocyte cell num... 1 | 26
increased hematocrit 1 | 36
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 93
shortened RR interval 1 | 19
thrombocytopenia 1 | 46

Disease

lung cancer 28 | 4,473
non-small cell lung cancer 25 | 2,798
ovarian cancer 25 | 8,491
ulcerative colitis 25 | 2,087
psoriasis 24 | 6,685
lung adenocarcinoma 23 | 2,714
lung carcinoma 23 | 2,844
interstitial cystitis 21 | 2,299
pancreatic ductal adenocarcinoma liver metastasis 20 | 1,795
osteosarcoma 19 | 7,933
intraductal papillary-mucinous adenoma (IPMA) 18 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 17 | 2,988
tuberculosis 17 | 1,563
invasive ductal carcinoma 16 | 2,950
glioblastoma 14 | 5,572
intraductal papillary-mucinous neoplasm (IPMN) 14 | 3,289
malignant mesothelioma 14 | 3,163
pancreatic cancer 14 | 2,300
Complement deficiency 13 | 15
adrenocortical carcinoma 13 | 1,427
periodontitis 13 | 269
pilocytic astrocytoma 13 | 3,086
chronic lymphosyte leukemia 12 | 232
subependymal giant cell astrocytoma 12 | 2,287
Age related macular degeneration 10 | 84
Cancer 10 | 2,346
Kidney disease 10 | 397
colon cancer 10 | 1,475
medulloblastoma, large-cell 10 | 6,234
Duchenne muscular dystrophy 9 | 602
Immunologic Deficiency Syndromes 9 | 16
Multiple myeloma 9 | 1,327
dermatomyositis 9 | 966
mucosa-associated lymphoid tissue lymphoma 9 | 480
primary Sjogren syndrome 9 | 788
Anemia 8 | 252
Breast cancer 8 | 3,098
Rheumatoid Arthritis 8 | 1,170
Vascular disease 8 | 281
acute quadriplegic myopathy 8 | 1,157
astrocytoma 8 | 1,493
cutaneous lupus erythematosus 8 | 1,056
juvenile dermatomyositis 8 | 1,189
limb girdle muscular dystrophy 2A 8 | 156
primary pancreatic ductal adenocarcinoma 8 | 1,271
systemic lupus erythematosus 8 | 172
IGA Glomerulonephritis 7 | 454
cystic fibrosis 7 | 1,670
esophageal adenocarcinoma 7 | 737
hemolytic-uremic syndrome 7 | 28
pituitary cancer 7 | 1,972
posterior fossa group A ependymoma 7 | 1,511
Atopic dermatitis 6 | 944
Atypical Hemolytic Uremic Syndrome 6 | 9
Becker muscular dystrophy 6 | 187
Carcinoma 6 | 2,147
Lupus erythematosus 6 | 80
Macular degeneration 6 | 44
Meningitis 6 | 46
Progressive relapsing multiple sclerosis 6 | 18
breast carcinoma 6 | 1,614
diabetes mellitus 6 | 1,663
gastric carcinoma 6 | 832
pediatric high grade glioma 6 | 2,712
sonic hedgehog group medulloblastoma 6 | 1,482
Amebiasis 5 | 22
Down syndrome 5 | 548
Leukemia 5 | 88
Lupus Erythematosus, Systemic 5 | 73
Lymphoma 5 | 57
Thrombocytopenia 5 | 105
atypical teratoid / rhabdoid tumor 5 | 4,369
autosomal dominant Emery-Dreifuss muscular dystrophy 5 | 499
cystic fibrosis and chronic rhinosinusitis 5 | 213
group 3 medulloblastoma 5 | 2,254
group 4 medulloblastoma 5 | 1,875
head and neck cancer and chronic obstructive pulmonary disease 5 | 237
nasopharyngeal carcinoma 5 | 1,056
oligodendroglioma 5 | 2,849
3MC syndrome 4 | 4
Chronic obstructive pulmonary disease 4 | 147
Type 1 diabetes mellitus 4 | 104
active Crohn's disease 4 | 918
aldosterone-producing adenoma 4 | 664
chronic kidney disease 4 | 90
ductal carcinoma in situ 4 | 1,745
interstitial lung disease 4 | 292
Arthritis 3 | 248
Atherosclerosis 3 | 275
Endometriosis 3 | 535
Juvenile arthritis 3 | 124
Malaria 3 | 140
Multiple Sclerosis 3 | 498
adult high grade glioma 3 | 2,148
astrocytic glioma 3 | 2,241
chronic rhinosinusitis 3 | 512
fibroadenoma 3 | 557
hepatocellular carcinoma 3 | 550
nephrosclerosis 3 | 329
pancreatic carcinoma 3 | 567

Tissue

Blood and immune system 91 | 17,994
Digestive Tract 91 | 18,472
Female tissues 91 | 18,646
Respiratory system 91 | 17,483
Skin and soft tissues 91 | 18,114
Liver and Pancreas 90 | 18,135
Urinary Tract 90 | 18,443
Cardiovascular System 88 | 17,957
Endocrine System 87 | 18,511
Nervous System 87 | 18,560
Male tissues 84 | 17,968

Target Family

Non-IDG 98 | 11,969
Enzyme 4 | 4,146
GPCR 3 | 408
Transcription Factor 1 | 1,400

Reactome Pathway

Complement cascade 106 | 106
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Complement receptor type 1 CR1 Tbio Non-IDG -3.34929 2279.9 502
Complement C3 C3 Tbio Non-IDG -3.54548 3337.1 965
Complement C5 C5 Tclin Non-IDG -2.22372 154.9 317
Collectin-10 COLEC10 Tbio Non-IDG -0.02576 5.25 61
Granzyme M GZMM Tbio Enzyme -2.62966 380.8 62
Ig lambda-6 chain C region IGLC6 Tdark Non-IDG -1.81183 228.7 0
Collectin-11 COLEC11 Tbio Non-IDG -1.28501 18.8 91
Membrane cofactor protein CD46 Tbio Non-IDG -2.92514 849.0 564
Complement C2 C2 Tbio Non-IDG -2.05345 88.6 180
Complement factor I CFI Tbio Non-IDG -2.46470 268.2 287