Development Level

Tdark 71 | 6,588
Tbio 48 | 11,445
Tchem 8 | 1,598
Tclin 5 | 613

IMPC Phenotype

cardiovascular system phenotyp... 2 | 36
decreased mean corpuscular vol... 2 | 79
increased circulating sodium l... 2 | 71
preweaning lethality, incomple... 2 | 499
abnormal behavior 1 | 298
abnormal kidney morphology 1 | 65
abnormal placement of pupils 1 | 6
abnormal seminal vesicle morph... 1 | 114
abnormal vertebrae morphology 1 | 18
decreased bone mineral content 1 | 151
decreased erythrocyte cell num... 1 | 62
decreased fasted circulating g... 1 | 65
decreased grip strength 1 | 116
decreased lymphocyte cell numb... 1 | 83
decreased prepulse inhibition 1 | 82
decreased red blood cell distr... 1 | 41
hyperactivity 1 | 148
hypoactivity 1 | 132
increased aggression 1 | 4
increased erythrocyte cell num... 1 | 39
increased heart rate variabili... 1 | 7
increased hematocrit 1 | 46
increased hemoglobin content 1 | 45
increased mean corpuscular hem... 1 | 96
increased monocyte cell number 1 | 63
increased neutrophil cell numb... 1 | 46
polycystic kidney 1 | 15
short tibia 1 | 97
shortened RR interval 1 | 17
small superior vagus ganglion 1 | 74
thrombocytopenia 1 | 56
tremors 1 | 39

Disease

Carcinoma 39 | 11,493
lung cancer 31 | 4,740
psoriasis 29 | 6,694
lung adenocarcinoma 27 | 2,716
non-small cell lung cancer 27 | 2,890
ovarian cancer 27 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 26 | 1,962
lung carcinoma 25 | 2,843
ulcerative colitis 25 | 1,819
Autosomal recessive predisposition 24 | 1,442
interstitial cystitis 24 | 2,312
osteosarcoma 23 | 7,950
tuberculosis 20 | 2,010
intraductal papillary-mucinous adenoma (IPMA) 19 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 18 | 2,989
periodontitis 18 | 293
malignant mesothelioma 17 | 3,232
glioblastoma 16 | 5,792
invasive ductal carcinoma 16 | 2,951
Age related macular degeneration 15 | 72
Cancer 15 | 2,499
Kidney disease 15 | 430
intraductal papillary-mucinous neoplasm (IPMN) 15 | 3,291
pancreatic cancer 14 | 2,398
Astrocytoma, Pilocytic 13 | 3,081
adrenocortical carcinoma 13 | 1,428
Complement deficiency 12 | 14
Immunologic Deficiency Syndromes 12 | 113
Systemic lupus erythematosus 12 | 194
subependymal giant cell astrocytoma 12 | 2,287
Anemia 11 | 365
Hemolytic-Uremic Syndrome 11 | 30
chronic lymphosyte leukemia 11 | 204
Breast cancer 10 | 3,578
Duchenne muscular dystrophy 10 | 601
Kidney cancer 10 | 2,613
Melanoma 10 | 711
Meningitis 10 | 67
Rheumatoid arthritis 10 | 1,191
colon cancer 10 | 1,478
dermatomyositis 10 | 966
ependymoma 10 | 4,679
medulloblastoma, large-cell 10 | 6,241
mucosa-associated lymphoid tissue lymphoma 10 | 484
primary Sjogren syndrome 10 | 735
Multiple myeloma 9 | 1,332
Vascular disease 9 | 319
cystic fibrosis 9 | 1,696
diabetes mellitus 9 | 1,728
juvenile dermatomyositis 9 | 1,187
limb girdle muscular dystrophy 2A 9 | 213
Lupus Erythematosus, Systemic 8 | 67
Skin cancer 8 | 469
acute quadriplegic myopathy 8 | 1,158
group 3 medulloblastoma 8 | 4,104
pituitary cancer 8 | 1,972
Atopic dermatitis 7 | 952
Atypical Hemolytic Uremic Syndrome 7 | 9
Increased susceptibility to bacterial infections 7 | 42
Liver Cirrhosis, Experimental 7 | 769
Macular degeneration 7 | 65
Pneumonia 7 | 174
Prone to bacterial infection 7 | 42
Recurrent bacterial infection 7 | 42
Schizophrenia 7 | 1,160
Thrombocytopenia 7 | 197
adult high grade glioma 7 | 3,801
atypical teratoid / rhabdoid tumor 7 | 5,112
autosomal dominant Emery-Dreifuss muscular dystrophy 7 | 510
breast carcinoma 7 | 1,638
cutaneous lupus erythematosus 7 | 1,057
nasopharyngeal carcinoma 7 | 1,058
primary pancreatic ductal adenocarcinoma 7 | 1,109
Arthritis 6 | 290
Autoimmune Diseases 6 | 67
HEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1 6 | 7
Progressive relapsing multiple sclerosis 6 | 19
Purpura 6 | 43
astrocytoma 6 | 1,146
esophageal adenocarcinoma 6 | 737
oligodendroglioma 6 | 2,850
sonic hedgehog group medulloblastoma 6 | 467
3MC syndrome 5 | 6
Asthma 5 | 385
Atherosclerosis 5 | 291
Becker muscular dystrophy 5 | 191
Bronchiectasis 5 | 64
Complement deficiency disease 5 | 6
Diarrhea 5 | 253
Liver disease 5 | 237
Lymphoma 5 | 81
Multiple Sclerosis 5 | 540
Skin disease 5 | 66
active ulcerative colitis 5 | 764
astrocytic glioma 5 | 2,597
chronic kidney disease 5 | 90
cystic fibrosis and chronic rhinosinusitis 5 | 214
ductal carcinoma in situ 5 | 1,745
gastric carcinoma 5 | 807
non-small cell lung carcinoma 5 | 317

Tissue

Liver and Pancreas 55 | 16,750
Urinary Tract 54 | 16,678
Endocrine System 52 | 18,159
Blood and immune system 48 | 16,909
Digestive Tract 48 | 17,369
Skin and soft tissues 48 | 17,230
Female tissues 47 | 17,400
Male tissues 46 | 17,142
Respiratory system 46 | 16,393
Nervous System 42 | 16,725
Cardiovascular System 40 | 15,192

Target Family

Non-IDG 118 | 12,091
Enzyme 10 | 4,145
GPCR 3 | 408
Transcription Factor 1 | 1,400

Reactome Pathway

Complement cascade 132 | 132
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Complement receptor type 1 CR1 Tbio Non-IDG -3.36509 2362.6 700
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 1D-39 IGKV1D-39 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 1-16 IGKV1-16 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 1-12 IGKV1-12 Tdark Non-IDG 0.00000 0
Immunoglobulin lambda constant 1 IGLC1 Tbio Non-IDG -1.96217 230.7 0
Complement factor H-related protein 5 CFHR5 Tbio Non-IDG -1.46067 30.5 146
Granzyme M GZMM Tbio Enzyme -2.65427 401.1 77
Immunoglobulin lambda constant 6 IGLC6 Tdark Non-IDG -1.96217 230.7 0
Membrane cofactor protein CD46 Tbio Non-IDG -2.94025 875.6 770