Development Level

Tbio 14 | 11,651
Tclin 4 | 612
Tchem 3 | 1,388

IMPC Phenotype

abnormal seminal vesicle morph... 2 | 114
enlarged heart 2 | 210
preweaning lethality, complete... 2 | 979
decreased bone mineral content 1 | 151
decreased circulating creatini... 1 | 39
decreased circulating phosphat... 1 | 27
decreased mean corpuscular vol... 1 | 79
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
pale yolk sac 1 | 25
preweaning lethality, incomple... 1 | 499
tremors 1 | 39

Disease

Carcinoma 16 | 11,493
Thrombophilia 15 | 38
Autosomal recessive predisposition 11 | 1,442
Cancer 10 | 2,499
Venous Thrombosis 10 | 47
Atherosclerosis 9 | 291
Cerebrovascular disease 9 | 238
Coronary artery disease 9 | 268
Pulmonary embolism 9 | 55
Thrombosis 9 | 46
lung cancer 9 | 4,740
ovarian cancer 9 | 8,520
pancreatic ductal adenocarcinoma liver metastasis 9 | 1,962
Disseminated intravascular coagulation 8 | 38
Epistaxis 8 | 43
Protein C deficiency 8 | 19
intraductal papillary-mucinous adenoma (IPMA) 8 | 2,955
lung carcinoma 8 | 2,843
lung adenocarcinoma 7 | 2,716
Deep Vein Thrombosis 6 | 8
Kidney cancer 6 | 2,613
Thrombocytopenia 6 | 197
Venous Thromboembolism 6 | 8
intraductal papillary-mucinous carcinoma (IPMC) 6 | 2,989
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
non-small cell lung cancer 6 | 2,890
pancreatic cancer 6 | 2,398
Blood protein disease 5 | 11
Congenital afibrinogenemia 5 | 11
Ecchymosis 5 | 66
Gingival Hemorrhage 5 | 18
Hemarthrosis 5 | 12
Hypertension 5 | 396
Increased tendency to bruise 5 | 66
Kidney disease 5 | 430
Purpura 5 | 43
Thrombophlebitis 5 | 19
Vascular disease 5 | 319
atypical teratoid / rhabdoid tumor 5 | 5,112
ductal carcinoma in situ 5 | 1,745
ependymoma 5 | 4,679
interstitial cystitis 5 | 2,312
invasive ductal carcinoma 5 | 2,951
osteosarcoma 5 | 7,950
ulcerative colitis 5 | 1,819
Antithrombin III deficiency 4 | 14
Blood Coagulation Disorders 4 | 42
Breast cancer 4 | 3,578
Gastrointestinal Hemorrhage 4 | 52
Hemophilia B 4 | 11
Liver disease 4 | 237
Lung disease 4 | 142
Myocardial Infarction 4 | 151
Partial thromboplastin time increased (finding) 4 | 11
Peripheral vascular disease 4 | 87
Placental abruption 4 | 18
Purpura fulminans 4 | 9
Thromboembolism 4 | 15
Thrombosis of cerebral veins 4 | 6
Vasculitis 4 | 80
astrocytic glioma 4 | 2,597
cystic fibrosis 4 | 1,696
diabetes mellitus 4 | 1,728
mucosa-associated lymphoid tissue lymphoma 4 | 484
oligodendroglioma 4 | 2,850
pancreatic carcinoma 4 | 562
psoriasis 4 | 6,694
tuberculosis 4 | 2,010
Alzheimer's disease 3 | 658
Anemia 3 | 365
Antiphospholipid syndrome 3 | 19
Astrocytoma, Pilocytic 3 | 3,081
Autoimmune Diseases 3 | 67
Bleeding tendency 3 | 37
Brain Ischemia 3 | 110
Budd-Chiari syndrome 3 | 12
Cerebrovascular accident 3 | 63
Cholestasis 3 | 155
Duchenne muscular dystrophy 3 | 601
Factor V deficiency 3 | 8
Heart disease 3 | 306
Highly variable severity 3 | 157
Hypersensitivity reaction type II disease 3 | 253
Hypofibrinogenemia 3 | 4
Joint swelling 3 | 26
Liver Cirrhosis 3 | 181
Liver Cirrhosis, Experimental 3 | 769
Lupus erythematosus 3 | 57
Menorrhagia 3 | 25
Portal vein thrombosis 3 | 12
Prenatal onset 3 | 139
Prevention of deep vein thrombosis 3 | 7
Prothrombin time increased 3 | 7
Respiratory Distress Syndrome, Adult 3 | 40
Spontaneous abortion 3 | 113
Stomach Neoplasms 3 | 300
Variable expressivity 3 | 157
adult high grade glioma 3 | 3,801
pituitary cancer 3 | 1,972
primary Sjogren syndrome 3 | 735

Tissue

Digestive Tract 21 | 17,369
Endocrine System 20 | 18,159
Liver and Pancreas 20 | 16,750
Skin and soft tissues 20 | 17,230
Urinary Tract 20 | 16,678
Blood and immune system 19 | 16,909
Female tissues 19 | 17,400
Male tissues 19 | 17,142
Respiratory system 18 | 16,393
Nervous System 17 | 16,725
Cardiovascular System 14 | 15,192

Target Family

Non-IDG 14 | 12,091
Enzyme 6 | 4,145
GPCR 1 | 408

Reactome Pathway

Common Pathway of Fibrin Clot ... 21 | 21
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Myeloblastin PRTN3 Tchem Enzyme -3.46597 2968.8 397
Platelet factor 4 PF4 Tbio Non-IDG -3.30967 2121.0 327
Antithrombin-III SERPINC1 Tclin Non-IDG -3.98451 9678.9 580
Fibrinogen beta chain FGB Tbio Non-IDG -2.09043 116.8 352
Coagulation factor XIII A chain F13A1 Tchem Enzyme -2.31587 200.8 726
Coagulation factor X F10 Tclin Enzyme -3.12757 1386.9 376
Vitamin K-dependent protein S PROS1 Tbio Non-IDG -3.36389 2143.9 268
Glia-derived nexin SERPINE2 Tbio Non-IDG -2.56699 376.5 215
Platelet factor 4 variant PF4V1 Tbio Non-IDG -1.35415 23.0 86
Coagulation factor VIII F8 Tbio Non-IDG -3.59602 3983.5 652