Development Level

Tbio 71 | 11,445
Tchem 11 | 1,598
Tdark 7 | 6,588

IMPC Phenotype

decreased grip strength 3 | 116
decreased total body fat amoun... 3 | 207
abnormal embryo size 2 | 220
abnormal femur morphology 2 | 14
abnormal skin morphology 2 | 50
decreased body length 2 | 101
decreased bone mineral density 2 | 126
decreased vertical activity 2 | 208
embryonic growth retardation 2 | 106
embryonic lethality prior to t... 2 | 278
impaired glucose tolerance 2 | 75
increased fasted circulating g... 2 | 76
preweaning lethality, incomple... 2 | 499
short tibia 2 | 97
abnormal bone structure 1 | 187
abnormal ear morphology 1 | 9
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal kidney morphology 1 | 65
abnormal lens morphology 1 | 81
abnormal limb position 1 | 3
abnormal pelvic girdle bone mo... 1 | 12
abnormal pericardium morpholog... 1 | 26
abnormal radius morphology 1 | 8
abnormal seminal vesicle morph... 1 | 114
abnormal sleep behavior 1 | 70
abnormal tibia morphology 1 | 14
abnormal tooth morphology 1 | 24
abnormal ulna morphology 1 | 8
convulsive seizures 1 | 13
decreased bone mineral content 1 | 151
decreased caudal vertebrae num... 1 | 53
decreased circulating amylase ... 1 | 28
decreased circulating aspartat... 1 | 34
decreased circulating bilirubi... 1 | 19
decreased circulating fructosa... 1 | 30
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased circulating total pr... 1 | 49
decreased eosinophil cell numb... 1 | 24
decreased erythrocyte cell num... 1 | 62
decreased heart rate 1 | 18
decreased hematocrit 1 | 46
decreased hemoglobin content 1 | 68
decreased lymphocyte cell numb... 1 | 83
decreased mean corpuscular hem... 1 | 50
decreased mean corpuscular vol... 1 | 79
decreased threshold for audito... 1 | 26
dilated heart left ventricle 1 | 11
embryonic lethality prior to o... 1 | 239
enlarged lymph nodes 1 | 37
increased blood urea nitrogen ... 1 | 48
increased body length 1 | 32
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating HDL chol... 1 | 80
increased circulating alkaline... 1 | 122
increased circulating amylase ... 1 | 25
increased circulating calcium ... 1 | 34
increased circulating choleste... 1 | 66
increased circulating creatini... 1 | 38
increased circulating phosphat... 1 | 26
increased circulating triglyce... 1 | 42
increased grip strength 1 | 41
increased heart weight 1 | 62
increased large unstained cell... 1 | 5
increased mean corpuscular hem... 1 | 36
increased neutrophil cell numb... 1 | 46
increased or absent threshold ... 1 | 101
increased red blood cell distr... 1 | 34
increased total body fat amoun... 1 | 134
increased vertical activity 1 | 24
persistence of hyaloid vascula... 1 | 33
preweaning lethality, complete... 1 | 979
prolonged RR interval 1 | 8
thin skin 1 | 2

Disease

Carcinoma 79 | 11,493
ovarian cancer 65 | 8,520
glioblastoma 56 | 5,792
Astrocytoma, Pilocytic 47 | 3,081
Breast cancer 46 | 3,578
ependymoma 45 | 4,679
atypical teratoid / rhabdoid tumor 44 | 5,112
lung cancer 44 | 4,740
Kidney cancer 41 | 2,613
non-small cell lung cancer 41 | 2,890
pancreatic cancer 41 | 2,398
psoriasis 41 | 6,694
osteosarcoma 40 | 7,950
malignant mesothelioma 37 | 3,232
lung adenocarcinoma 36 | 2,716
medulloblastoma, large-cell 36 | 6,241
Autosomal recessive predisposition 35 | 1,442
interstitial cystitis 35 | 2,312
adult high grade glioma 31 | 3,801
intraductal papillary-mucinous adenoma (IPMA) 30 | 2,955
intraductal papillary-mucinous neoplasm (IPMN) 30 | 3,291
intraductal papillary-mucinous carcinoma (IPMC) 29 | 2,989
invasive ductal carcinoma 29 | 2,951
cystic fibrosis 28 | 1,696
pituitary cancer 28 | 1,972
Duchenne muscular dystrophy 25 | 601
breast carcinoma 25 | 1,638
gastric carcinoma 25 | 807
primitive neuroectodermal tumor 25 | 3,035
ulcerative colitis 24 | 1,819
lung carcinoma 23 | 2,843
esophageal adenocarcinoma 20 | 737
nasopharyngeal carcinoma 20 | 1,058
primary pancreatic ductal adenocarcinoma 20 | 1,109
Liver Cirrhosis, Experimental 19 | 769
Short stature 19 | 531
group 3 medulloblastoma 19 | 4,104
juvenile dermatomyositis 19 | 1,187
pancreatic ductal adenocarcinoma liver metastasis 19 | 1,962
ductal carcinoma in situ 18 | 1,745
Acquired scoliosis 17 | 281
Curvature of spine 17 | 282
Myopia 17 | 176
autosomal dominant Emery-Dreifuss muscular dystrophy 17 | 510
subependymal giant cell astrocytoma 17 | 2,287
Cancer 16 | 2,499
Skin cancer 16 | 469
Degenerative polyarthritis 15 | 115
Melanoma 15 | 711
oligodendroglioma 15 | 2,850
urothelial carcinoma 15 | 318
Becker muscular dystrophy 14 | 191
Hypoplastic mandible condyle 14 | 275
Mandibular hypoplasia 14 | 275
Micrognathism 14 | 275
Platyspondyly 14 | 56
colon cancer 14 | 1,478
group 4 medulloblastoma 14 | 1,855
interstitial lung disease 14 | 298
pediatric high grade glioma 14 | 1,064
Atrophic scar 13 | 18
Cataract 13 | 297
Dental caries 13 | 164
Liver cancer 13 | 604
Osteoarthritis 13 | 184
diabetes mellitus 13 | 1,728
tuberculosis 13 | 2,010
Hyperkyphosis 12 | 111
Kyphosis deformity of spine 12 | 114
Pick disease 12 | 1,894
active Crohn's disease 12 | 922
adrenocortical carcinoma 12 | 1,428
limb girdle muscular dystrophy 2A 12 | 213
Abortion, Spontaneous 11 | 109
Atopic dermatitis 11 | 952
Joint hyperflexibility 11 | 78
Osteogenesis imperfecta 11 | 34
Respiratory Insufficiency 11 | 132
Respiratory function loss 11 | 121
Spontaneous abortion 11 | 113
astrocytic glioma 11 | 2,597
astrocytoma 11 | 1,146
cutaneous lupus erythematosus 11 | 1,057
Blue sclera 10 | 32
Congenital clubfoot 10 | 109
Contracture 10 | 96
Contracture of joint 10 | 93
Ehlers-Danlos syndrome 10 | 43
Epidermolysis bullosa 10 | 21
Flexion contracture 10 | 93
Flexion contractures of joints 10 | 93
Hernia, Inguinal 10 | 89
Hypotrophic malar bone 10 | 129
Lens Opacities 10 | 231
Malar flattening 10 | 129
Rotting teeth 10 | 73
fibroadenoma 10 | 559
head and neck cancer and chronic obstructive pulmonary disease 10 | 239
periodontitis 9 | 293
pterygium 9 | 76

Tissue

Endocrine System 89 | 18,159
Female tissues 89 | 17,400
Blood and immune system 88 | 16,909
Digestive Tract 88 | 17,369
Male tissues 88 | 17,142
Skin and soft tissues 86 | 17,230
Urinary Tract 86 | 16,678
Liver and Pancreas 85 | 16,750
Nervous System 85 | 16,725
Respiratory system 82 | 16,393
Cardiovascular System 81 | 15,192

Target Family

Non-IDG 59 | 12,091
Enzyme 30 | 4,145

Reactome Pathway

Collagen formation 89 | 89
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Collagen alpha-1(IV) chain COL4A1 Tbio Non-IDG -2.28595 186.9 391
Collagen alpha-1(VIII) chain COL8A1 Tbio Non-IDG -1.31054 16.6 116
Collagen alpha-1(XXVIII) chain COL28A1 Tdark Non-IDG 0.78 0.10 6
Collagen alpha-1(XXV) chain COL25A1 Tbio Non-IDG -0.99093 10.6 119
Collagen alpha-2(V) chain COL5A2 Tbio Non-IDG -1.69982 44.6 96
Collagen alpha-1(XIX) chain COL19A1 Tbio Non-IDG -0.75672 6.18 137
Collagen alpha-1(XXI) chain COL21A1 Tbio Non-IDG -0.67130 4.90 89
Collagen alpha-1(XXIII) chain COL23A1 Tbio Non-IDG -0.49550 1.85 112
Collagen alpha-1(XII) chain COL12A1 Tbio Non-IDG -1.36571 21.4 38
Collagen alpha-1(XVIII) chain COL18A1 Tbio Non-IDG -3.18339 1561.4 433