Development Level

Tchem 21 | 1,598
Tbio 15 | 11,445
Tdark 2 | 6,588
Tclin 1 | 613

IMPC Phenotype

preweaning lethality, incomple... 3 | 499
short tibia 3 | 97
abnormal skin coloration 2 | 25
abnormal vibrissa morphology 2 | 25
abnormal ear morphology 1 | 9
abnormal esophagus morphology 1 | 5
abnormal femur morphology 1 | 14
abnormal heart morphology 1 | 162
abnormal humerus morphology 1 | 11
abnormal joint morphology 1 | 23
abnormal pancreas morphology 1 | 13
abnormal pelvic girdle bone mo... 1 | 12
abnormal radius morphology 1 | 8
abnormal tail morphology 1 | 25
abnormal thyroid gland morphol... 1 | 3
abnormal tibia morphology 1 | 14
abnormal trachea morphology 1 | 3
abnormal ulna morphology 1 | 8
absent lymph nodes 1 | 3
anophthalmia 1 | 33
athymia 1 | 2
brachydactyly 1 | 19
decreased T cell number 1 | 15
decreased bone mineral content 1 | 151
decreased bone mineral density 1 | 126
decreased circulating alkaline... 1 | 46
decreased circulating aspartat... 1 | 34
decreased circulating chloride... 1 | 30
decreased circulating creatini... 1 | 39
decreased circulating free fat... 1 | 31
decreased circulating phosphat... 1 | 27
decreased circulating triglyce... 1 | 79
decreased eosinophil cell numb... 1 | 24
decreased prepulse inhibition 1 | 82
decreased total body fat amoun... 1 | 207
embryonic lethality prior to t... 1 | 278
enlarged lymph nodes 1 | 37
enlarged spleen 1 | 41
hypoactivity 1 | 132
impaired glucose tolerance 1 | 75
increased bone mineral content 1 | 108
increased bone mineral density 1 | 72
increased circulating alkaline... 1 | 122
increased fasted circulating g... 1 | 76
increased or absent threshold ... 1 | 101
increased vertical activity 1 | 24
premature death 1 | 5
preweaning lethality, complete... 1 | 979
small superior vagus ganglion 1 | 74

Disease

Carcinoma 31 | 11,493
ovarian cancer 22 | 8,520
Cancer 20 | 2,499
glioblastoma 17 | 5,792
osteosarcoma 17 | 7,950
psoriasis 17 | 6,694
Breast cancer 15 | 3,578
atypical teratoid / rhabdoid tumor 15 | 5,112
non-small cell lung cancer 15 | 2,890
pancreatic cancer 15 | 2,398
Astrocytoma, Pilocytic 14 | 3,081
lung cancer 14 | 4,740
malignant mesothelioma 14 | 3,232
cystic fibrosis 13 | 1,696
ulcerative colitis 13 | 1,819
Autosomal recessive predisposition 12 | 1,442
lung adenocarcinoma 12 | 2,716
invasive ductal carcinoma 11 | 2,951
Vascular disease 10 | 319
interstitial cystitis 10 | 2,312
intraductal papillary-mucinous neoplasm (IPMN) 10 | 3,291
lung carcinoma 10 | 2,843
periodontitis 10 | 293
primary pancreatic ductal adenocarcinoma 10 | 1,109
Alzheimer's disease 9 | 658
Arthritis 9 | 290
breast carcinoma 9 | 1,638
intraductal papillary-mucinous adenoma (IPMA) 9 | 2,955
medulloblastoma, large-cell 9 | 6,241
Atopic dermatitis 8 | 952
Kidney cancer 8 | 2,613
Liver Cirrhosis, Experimental 8 | 769
cutaneous lupus erythematosus 8 | 1,057
diabetes mellitus 8 | 1,728
ependymoma 8 | 4,679
intraductal papillary-mucinous carcinoma (IPMC) 8 | 2,989
Abortion, Spontaneous 7 | 109
Degenerative disc disease 7 | 35
Neoplasm Invasiveness 7 | 161
Rheumatoid arthritis 7 | 1,191
Short stature 7 | 531
Spontaneous abortion 7 | 113
ductal carcinoma in situ 7 | 1,745
gastric carcinoma 7 | 807
group 3 medulloblastoma 7 | 4,104
pituitary cancer 7 | 1,972
subependymal giant cell astrocytoma 7 | 2,287
Abnormality of epiphysis morphology 6 | 39
Duchenne muscular dystrophy 6 | 601
Hypoplastic mandible condyle 6 | 275
Mandibular hypoplasia 6 | 275
Micrognathism 6 | 275
adult high grade glioma 6 | 3,801
interstitial lung disease 6 | 298
nasopharyngeal carcinoma 6 | 1,058
pediatric high grade glioma 6 | 1,064
tuberculosis 6 | 2,010
Breast Neoplasms 5 | 445
Degenerative polyarthritis 5 | 115
Dental caries 5 | 164
Gait abnormality 5 | 135
Heart disease 5 | 306
Mammary Neoplasms 5 | 425
Osteoarthritis 5 | 184
Osteoporosis 5 | 363
Prostatic Neoplasms 5 | 495
Skin cancer 5 | 469
acute quadriplegic myopathy 5 | 1,158
group 4 medulloblastoma 5 | 1,855
head and neck cancer and chronic obstructive pulmonary disease 5 | 239
pancreatic ductal adenocarcinoma liver metastasis 5 | 1,962
primitive neuroectodermal tumor 5 | 3,035
Arthralgia 4 | 90
Arthritis, Rheumatoid 4 | 174
Asthma 4 | 385
Hip Dislocation, Congenital 4 | 48
Hypotrophic malar bone 4 | 129
Inflammatory bowel disease 4 | 151
Knee joint valgus deformity 4 | 56
Liver disease 4 | 237
Lung disease 4 | 142
Malar flattening 4 | 129
Multiple Sclerosis 4 | 540
Neoplasm Metastasis 4 | 168
Platyspondyly 4 | 56
Rotting teeth 4 | 73
Skin disease 4 | 66
Synovitis 4 | 78
active Crohn's disease 4 | 922
astrocytoma 4 | 1,146
colon cancer 4 | 1,478
esophageal adenocarcinoma 4 | 737
inflammatory breast cancer 4 | 286
mucosa-associated lymphoid tissue lymphoma 4 | 484
primary Sjogren syndrome 4 | 735
urothelial carcinoma 4 | 318
Endometriosis 3 | 540
autosomal dominant Emery-Dreifuss muscular dystrophy 3 | 510
fibroadenoma 3 | 559
progressive supranuclear palsy 3 | 676

Tissue

Blood and immune system 39 | 16,909
Digestive Tract 39 | 17,369
Female tissues 39 | 17,400
Urinary Tract 39 | 16,678
Endocrine System 38 | 18,159
Liver and Pancreas 37 | 16,750
Male tissues 37 | 17,142
Skin and soft tissues 37 | 17,230
Respiratory system 36 | 16,393
Nervous System 34 | 16,725
Cardiovascular System 30 | 15,192

Target Family

Enzyme 22 | 4,145
Non-IDG 17 | 12,091

Reactome Pathway

Collagen degradation 39 | 39
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Collagen alpha-1(XXIII) chain COL23A1 Tbio Non-IDG -0.49550 1.85 112
Collagen alpha-1(XII) chain COL12A1 Tbio Non-IDG -1.36571 21.4 38
Disintegrin and metalloproteinase domain-containing protein 9 ADAM9 Tchem Enzyme -2.08807 122.3 258
Collagen alpha-1(XV) chain COL15A1 Tbio Non-IDG -1.18716 15.5 74
Collagen alpha-1(XVIII) chain COL18A1 Tbio Non-IDG -3.18339 1561.4 433
Collagen alpha-1(XVI) chain COL16A1 Tbio Non-IDG -0.91124 6.99 35
Collagen alpha-1(XVII) chain COL17A1 Tbio Non-IDG -2.75473 576.3 123
Collagen alpha-1(XIX) chain COL19A1 Tbio Non-IDG -0.75672 6.18 137
Matrix metalloproteinase-15 MMP15 Tchem Enzyme -1.69065 43.4 351
Transmembrane protease serine 6 TMPRSS6 Tchem Enzyme -2.03522 125.4 122