Development Level

Tdark 57 | 7,003
Tbio 10 | 10,625
Tchem 1 | 1,890
Tclin 1 | 602

IMPC Phenotype

decreased circulating glucose ... 1 | 121

Disease

interstitial cystitis 13 | 2,299
ulcerative colitis 13 | 2,087
lung cancer 10 | 4,473
periodontitis 10 | 269
psoriasis 10 | 6,685
tuberculosis 10 | 1,563
lung adenocarcinoma 9 | 2,714
non-small cell lung cancer 9 | 2,798
osteosarcoma 9 | 7,933
chronic lymphosyte leukemia 8 | 232
Multiple myeloma 7 | 1,327
ovarian cancer 7 | 8,491
invasive ductal carcinoma 6 | 2,950
lung carcinoma 6 | 2,844
Amebiasis 5 | 22
Leukemia 5 | 88
Lymphoma 5 | 57
acute quadriplegic myopathy 5 | 1,157
adrenocortical carcinoma 5 | 1,427
cutaneous lupus erythematosus 5 | 1,056
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
juvenile dermatomyositis 5 | 1,189
medulloblastoma, large-cell 5 | 6,234
pancreatic cancer 5 | 2,300
pilocytic astrocytoma 5 | 3,086
primary Sjogren syndrome 5 | 788
primary pancreatic ductal adenocarcinoma 5 | 1,271
subependymal giant cell astrocytoma 5 | 2,287
Becker muscular dystrophy 4 | 187
Chronic obstructive pulmonary disease 4 | 147
Duchenne muscular dystrophy 4 | 602
Lupus erythematosus 4 | 80
colon cancer 4 | 1,475
cystic fibrosis and chronic rhinosinusitis 4 | 213
diabetes mellitus 4 | 1,663
esophageal adenocarcinoma 4 | 737
glioblastoma 4 | 5,572
head and neck cancer and chronic obstructive pulmonary disease 4 | 237
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
limb girdle muscular dystrophy 2A 4 | 156
pediatric high grade glioma 4 | 2,712
C1q DEFICIENCY 3 | 3
Complement component C1q deficiency 3 | 3
Myositis 3 | 24
astrocytoma 3 | 1,493
cystic fibrosis 3 | 1,670
dermatomyositis 3 | 966
non-small cell lung carcinoma 3 | 413
posterior fossa group A ependymoma 3 | 1,511
sonic hedgehog group medulloblastoma 3 | 1,482
systemic lupus erythematosus 3 | 172
Angioedema 2 | 36
Complement deficiency 2 | 15
Down syndrome 2 | 548
Ehlers-Danlos syndrome 2 | 42
Ehlers-Danlos syndrome, periodontitis type 2 | 2
IGA Glomerulonephritis 2 | 454
Immunoglobulin kappa light chain deficiency 2 | 2
Kappa-Chain Deficiency 2 | 2
Lupus Erythematosus, Systemic 2 | 73
Myocardial Ischemia 2 | 169
Polycystic Ovary Syndrome 2 | 334
Rheumatoid Arthritis 2 | 1,170
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
chronic kidney disease 2 | 90
gastric carcinoma 2 | 832
malignant mesothelioma 2 | 3,163
mucosa-associated lymphoid tissue lymphoma 2 | 480
nasopharyngeal carcinoma 2 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
pituitary cancer 2 | 1,972
Age related macular degeneration 1 | 84
Anxiety Disorders 1 | 37
Aortic aneurysm 1 | 34
Arthritis, Experimental 1 | 39
Bilirubin metabolic disorder 1 | 39
Connective tissue disease 1 | 59
Diabetic Retinopathy 1 | 53
Diarrhea 1 | 155
Gastroenteritis 1 | 46
Heart Diseases 1 | 42
Human immunodeficiency virus infectious disease 1 | 129
Hyperglycemia 1 | 120
Hypertriglyceridemia 1 | 18
Intestinal obstruction 1 | 16
Nephritis 1 | 63
Obstructive sleep apnea 1 | 28
Ovarian Cysts 1 | 34
Pancreatitis 1 | 97
Pelvic inflammatory disease 1 | 21
Pericarditis 1 | 14
Pleural empyema 1 | 10
Septic arthritis 1 | 8
Subacute thyroiditis 1 | 5
Subdural empyema 1 | 7
Substance Withdrawal Syndrome 1 | 55
Tonsillitis 1 | 18
Transient cerebral ischemia 1 | 14
adult-onset Still's disease 1 | 6

Tissue

Blood and immune system 54 | 17,994
Digestive Tract 54 | 18,472
Female tissues 54 | 18,646
Respiratory system 54 | 17,483
Skin and soft tissues 54 | 18,114
Liver and Pancreas 53 | 18,135
Urinary Tract 53 | 18,443
Cardiovascular System 51 | 17,957
Endocrine System 50 | 18,511
Nervous System 50 | 18,560
Male tissues 48 | 17,968

Target Family

Non-IDG 69 | 11,969

Reactome Pathway

Classical antibody-mediated co... 69 | 69
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Ig lambda-6 chain C region IGLC6 Tdark Non-IDG -1.81183 228.7 0
Immunoglobulin heavy variable 3-7 IGHV3-7 Tdark Non-IDG 0.00000 0
Immunoglobulin heavy variable 3-33 IGHV3-33 Tdark Non-IDG 0.00000 0
Immunoglobulin heavy variable 1-46 IGHV1-46 Tdark Non-IDG 0.00000 0
Immunoglobulin heavy variable 1-69 IGHV1-69 Tdark Non-IDG 0.00000 0
Complement C1r subcomponent C1R Tclin Non-IDG -2.51843 309.1 170
Ig lambda-7 chain C region IGLC7 Tdark Non-IDG -1.81183 228.7 0
Ig gamma-2 chain C region IGHG2 Tbio Non-IDG 0.00000 0
Ig gamma-1 chain C region IGHG1 Tbio Non-IDG 0.00000 0
Ig kappa chain C region IGKC Tbio Non-IDG 0.00000 0