Development Level

Tdark 57 | 7,003
Tbio 10 | 10,625
Tchem 1 | 1,890
Tclin 1 | 602

IMPC Term

decreased circulating glucose ... 1 | 121

Disease

interstitial cystitis 13 | 2,299
ulcerative colitis 13 | 2,087
lung cancer 10 | 4,466
periodontitis 10 | 269
psoriasis 10 | 6,685
tuberculosis 10 | 1,557
lung adenocarcinoma 9 | 2,713
non-small cell lung cancer 9 | 2,798
osteosarcoma 9 | 7,933
chronic lymphosyte leukemia 8 | 232
ovarian cancer 7 | 8,484
Multiple myeloma 6 | 1,327
invasive ductal carcinoma 6 | 2,950
lung carcinoma 6 | 2,844
Amebiasis 5 | 22
Leukemia 5 | 88
Lymphoma 5 | 56
acute quadriplegic myopathy 5 | 1,157
adrenocortical carcinoma 5 | 1,427
cutaneous lupus erythematosus 5 | 1,056
intraductal papillary-mucinous adenoma (IPMA) 5 | 2,956
juvenile dermatomyositis 5 | 1,189
medulloblastoma, large-cell 5 | 6,234
pancreatic cancer 5 | 2,300
pilocytic astrocytoma 5 | 3,086
primary Sjogren syndrome 5 | 789
primary pancreatic ductal adenocarcinoma 5 | 1,271
subependymal giant cell astrocytoma 5 | 2,287
Becker muscular dystrophy 4 | 187
Chronic obstructive pulmonary disease 4 | 146
Duchenne muscular dystrophy 4 | 602
Lupus erythematosus 4 | 80
colon cancer 4 | 1,475
cystic fibrosis and chronic rhinosinusitis 4 | 213
diabetes mellitus 4 | 1,663
esophageal adenocarcinoma 4 | 737
glioblastoma 4 | 5,572
head and neck cancer and chronic obstructive pulmonary disease 4 | 237
intraductal papillary-mucinous carcinoma (IPMC) 4 | 2,988
intraductal papillary-mucinous neoplasm (IPMN) 4 | 3,289
limb girdle muscular dystrophy 2A 4 | 156
pediatric high grade glioma 4 | 2,712
C1q DEFICIENCY 3 | 3
Myositis 3 | 24
astrocytoma 3 | 1,493
cystic fibrosis 3 | 1,665
dermatomyositis 3 | 933
non-small cell lung carcinoma 3 | 413
posterior fossa group A ependymoma 3 | 1,511
sonic hedgehog group medulloblastoma 3 | 1,482
Angioedema 2 | 36
Complement deficiency 2 | 15
Down syndrome 2 | 548
Ehlers-Danlos syndrome 2 | 42
IGA Glomerulonephritis 2 | 454
Kappa-Chain Deficiency 2 | 2
Lupus Erythematosus, Systemic 2 | 73
Myocardial Ischemia 2 | 169
Polycystic Ovary Syndrome 2 | 332
Rheumatoid Arthritis 2 | 1,160
autosomal dominant Emery-Dreifuss muscular dystrophy 2 | 499
chronic kidney disease 2 | 90
gastric carcinoma 2 | 832
malignant mesothelioma 2 | 3,162
mucosa-associated lymphoid tissue lymphoma 2 | 480
nasopharyngeal carcinoma 2 | 1,056
pancreatic ductal adenocarcinoma liver metastasis 2 | 1,795
pituitary cancer 2 | 1,972
systemic lupus erythematosus 2 | 156
Age related macular degeneration 1 | 84
Anxiety Disorders 1 | 37
Aortic aneurysm 1 | 34
Arthritis, Experimental 1 | 39
Bilirubin metabolic disorder 1 | 39
Brain disease 1 | 83
Connective tissue disease 1 | 59
Diabetic Retinopathy 1 | 53
Diarrhea 1 | 155
Fatty liver disease 1 | 84
Gastroenteritis 1 | 46
Human immunodeficiency virus infectious disease 1 | 92
Hyperglycemia 1 | 120
Hypertriglyceridemia 1 | 18
Hyperuricemia 1 | 35
Intestinal obstruction 1 | 16
Nephritis 1 | 29
Obstructive sleep apnea 1 | 28
Osteoarthritis 1 | 96
Ovarian Cysts 1 | 34
Pancreatitis 1 | 97
Pelvic inflammatory disease 1 | 21
Pericarditis 1 | 14
Septic arthritis 1 | 8
Subacute thyroiditis 1 | 5
Subdural empyema 1 | 7
Substance Withdrawal Syndrome 1 | 52
Tonsillitis 1 | 18
Transient cerebral ischemia 1 | 14
adult-onset Still's disease 1 | 6
non-small cell lung cancer and chronic obstructive pulmonary disease 1 | 7

Tissue

Blood and immune system 54 | 17,995
Digestive Tract 54 | 18,473
Female tissues 54 | 18,647
Respiratory system 54 | 17,484
Skin and soft tissues 54 | 18,115
Liver and Pancreas 53 | 18,136
Urinary Tract 53 | 18,444
Cardiovascular System 51 | 17,958
Endocrine System 50 | 18,512
Nervous System 50 | 18,561
Male tissues 48 | 17,969

Target Family

Non-IDG 69 | 11,971

Reactome Pathway

Classical antibody-mediated co... 69 | 69
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Immunoglobulin kappa variable 3-11 IGKV3-11 Tdark Non-IDG 0.00000 0
C-reactive protein CRP Tbio Non-IDG -4.51399 33883.5 1160
Complement C1q subcomponent subunit C C1QC Tbio Non-IDG -1.27032 17.5 141
Complement C1q subcomponent subunit B C1QB Tbio Non-IDG -1.63026 41.3 161
Complement C1q subcomponent subunit A C1QA Tbio Non-IDG -1.71898 50.3 208
Ig lambda-7 chain C region IGLC7 Tdark Non-IDG 228.7 0
Immunoglobulin lambda variable 1-44 IGLV1-44 Tdark Non-IDG 0.00000 0
Immunoglobulin heavy variable 1-2 IGHV1-2 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 3-15 IGKV3-15 Tdark Non-IDG 0.00000 0
Immunoglobulin kappa variable 2-28 IGKV2-28 Tdark Non-IDG 0.00000 0