Development Level

Tbio 23 | 10,625
Tchem 10 | 1,890
Tdark 4 | 7,003
Tclin 3 | 602

Collection

Eligible non-olfactory GPCR Proteins 23 | 143

IMPC Term

cataract 1 | 26
hyperactivity 1 | 108
impaired pupillary reflex 1 | 14
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased heart weight 1 | 37
mydriasis 1 | 9

Disease

medulloblastoma, large-cell 13 | 6,234
psoriasis 11 | 6,685
Carcinoma 10 | 2,147
Schizophrenia 7 | 501
adult high grade glioma 7 | 2,148
Autistic Disorder 6 | 320
Epilepsy 6 | 346
atypical teratoid / rhabdoid tumor 6 | 4,369
glioblastoma 6 | 5,572
osteosarcoma 6 | 7,933
primitive neuroectodermal tumor 6 | 3,031
Epilepsy, Temporal Lobe 5 | 23
Pelvic inflammatory disease 5 | 21
lung cancer 5 | 4,466
oligodendroglioma 5 | 2,849
pilocytic astrocytoma 5 | 3,086
Alcohol dependence 4 | 107
Attention deficit hyperactivity disorder 4 | 156
Parkinson's disease 4 | 364
Toxic encephalopathy 4 | 131
diabetes mellitus 4 | 1,663
posterior fossa group A ependymoma 4 | 1,511
subependymal giant cell astrocytoma 4 | 2,287
Alcoholic Intoxication, Chronic 3 | 41
Major Depressive Disorder 3 | 106
Melanoma 3 | 261
Narcolepsy 3 | 58
Nicotine dependence 3 | 53
Pick disease 3 | 1,893
astrocytic glioma 3 | 2,241
ependymoma 3 | 2,514
lung carcinoma 3 | 2,844
ovarian cancer 3 | 8,484
pituitary cancer 3 | 1,972
sonic hedgehog group medulloblastoma 3 | 1,482
Acquired immunodeficiency syndrome 2 | 164
Bipolar Disorder 2 | 266
Breast cancer 2 | 3,094
Cataplexy and narcolepsy 2 | 3
Cocaine-Related Disorders 2 | 88
Fragile X syndrome 2 | 31
Muscle Spasticity of Cerebral Origin 2 | 8
Muscle spasticity of spinal origin 2 | 8
Status Epilepticus 2 | 85
Substance-Related Disorders 2 | 114
astrocytoma 2 | 1,493
medulloblastoma 2 | 1,524
pediatric high grade glioma 2 | 2,712
tuberculosis 2 | 1,557
Adenoma 1 | 165
Amphetamine-Related Disorders 1 | 74
Amyotrophic Lateral Sclerosis 1 | 431
Anxiety Disorders 1 | 37
Asthenopia 1 | 11
Basal ganglia calcification 1 | 17
Calcinosis 1 | 62
Cardiovascular system disease 1 | 194
Cerebellar Ataxia 1 | 72
Cocaine dependence 1 | 24
Common cold 1 | 63
Congenital stationary night blindness 1 | 27
Dental caries 1 | 67
Disease of metabolism 1 | 15
Disuse amblyopia 1 | 3
Fibroma 1 | 16
Gastroesophageal reflux disease 1 | 37
Gliosis 1 | 16
Huntington's disease 1 | 72
Hyperactive behavior 1 | 31
Hypercalcemia 1 | 37
Hyperhomocysteinemia 1 | 34
Hyperparathyroidism 1 | 43
Hyperphosphatemia 1 | 32
Hypertension 1 | 287
Hypoparathyroidism 1 | 29
Hypophosphatemia 1 | 31
Idiopathic generalized epilepsy 1 | 15
Kidney disease 1 | 396
Mental depression 1 | 58
Multiple Sclerosis 1 | 498
Myopia 1 | 99
Nerve Degeneration 1 | 73
Neuralgia 1 | 16
Neurodegenerative disease 1 | 383
Night Blindness 1 | 39
Osteoporosis 1 | 257
Panic disorder 1 | 55
Prostate cancer 1 | 172
Psychoses, Substance-Induced 1 | 17
Rectal neoplasm 1 | 7
Retinitis 1 | 9
Secondary hyperparathyroidism 1 | 5
Small cell carcinoma of lung 1 | 45
Stomatitis 1 | 19
Type 2 diabetes mellitus 1 | 189
adrenocortical adenoma 1 | 134
atypical teratoid/rhabdoid tumor 1 | 1,095
glioblastoma multiforme 1 | 347
interstitial lung disease 1 | 291
substance-related disorder 1 | 105

Tissue

Female tissues 38 | 18,647
Nervous System 38 | 18,561
Urinary Tract 38 | 18,444
Digestive Tract 36 | 18,473
Endocrine System 36 | 18,512
Blood and immune system 33 | 17,995
Cardiovascular System 33 | 17,958
Skin and soft tissues 33 | 18,115
Liver and Pancreas 31 | 18,136
Male tissues 30 | 17,969
Respiratory system 29 | 17,484

Target Family

GPCR 39 | 406
Non-IDG 1 | 11,971

Reactome Pathway

Class C/3 (Metabotropic glutam... 40 | 40
Signal Transduction 2,516 | 2,516
Immune System 2,184 | 2,184
Metabolism 2,132 | 2,132
Gene Expression 1,755 | 1,755
Metabolism of proteins 1,545 | 1,545
Innate Immune System 1,376 | 1,376
Signaling by GPCR 1,330 | 1,330
Developmental Biology 1,029 | 1,029
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,005 | 1,005
Adaptive Immune System 939 | 939
Disease 856 | 856
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 804 | 804
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 669 | 669
Membrane Trafficking 608 | 608
Cell Cycle 573 | 573
Axon guidance 542 | 542
Neutrophil degranulation 542 | 542
Signaling by Interleukins 501 | 501
Cell Cycle, Mitotic 471 | 471
Signalling by NGF 468 | 468
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 436 | 436
Class I MHC mediated antigen p... 431 | 431
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 424 | 424
Cellular responses to stress 416 | 416
DAP12 interactions 410 | 410
Infectious disease 392 | 392
NGF signalling via TRKA from t... 379 | 379
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 368 | 368
Diseases of signal transductio... 360 | 360
Signaling by EGFR 356 | 356
Transcriptional Regulation by ... 356 | 356
Metabolism of amino acids and ... 354 | 354
DAP12 signaling 347 | 347
Downstream signal transduction 344 | 344
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 330 | 330
Signaling by SCF-KIT 328 | 328
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 322 | 322
FCERI mediated MAPK activation 317 | 317
Signaling by Insulin receptor 313 | 313
Antigen processing: Ubiquitina... 302 | 302
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 291 | 291
Signaling by Wnt 291 | 291
IGF1R signaling cascade 290 | 290
IRS-related events triggered b... 290 | 290
Insulin receptor signalling ca... 289 | 289
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 286 | 286
MAPK family signaling cascades 284 | 284
Signaling by the B Cell Recept... 283 | 283
Asparagine N-linked glycosylat... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 278 | 278
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 269 | 269
M Phase 267 | 267
Interleukin-3, 5 and GM-CSF si... 263 | 263
RET signaling 262 | 262
Signalling to ERKs 255 | 255
Interleukin-2 signaling 254 | 254
Immunoregulatory interactions ... 252 | 252
VEGFR2 mediated cell prolifera... 250 | 250
RHO GTPase Effectors 249 | 249
Signalling to RAS 248 | 248
Interleukin receptor SHC signa... 247 | 247
G alpha (i) signalling events 245 | 245
Signaling by Leptin 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Prolonged ERK activation event... 244 | 244
MAPK1/MAPK3 signaling 243 | 243
Frs2-mediated activation 242 | 242
HIV Infection 242 | 242
ARMS-mediated activation 241 | 241
Signalling to p38 via RIT and ... 241 | 241
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 237 | 237
RAF/MAP kinase cascade 237 | 237
SHC1 events in EGFR signaling 237 | 237
SOS-mediated signalling 237 | 237
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Ub-specific processing proteas... 203 | 203

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Taste receptor type 1 member 3 TAS1R3 Tbio GPCR -2.19758 165.4 232
Taste receptor type 1 member 1 TAS1R1 Tbio GPCR -1.71516 50.8 165
Taste receptor type 2 member 42 TAS2R42 Tdark GPCR 0.11 0.69 13
Taste receptor type 2 member 4 TAS2R4 Tchem GPCR -1.19643 16.4 23
Taste receptor type 2 member 3 TAS2R3 Tbio GPCR -0.48474 3.19 77
Taste receptor type 2 member 1 TAS2R1 Tbio GPCR -1.00553 9.94 92
Taste receptor type 2 member 10 TAS2R10 Tbio GPCR -0.51188 3.76 77
Taste receptor type 2 member 9 TAS2R9 Tdark GPCR -0.24967 1.64 72
Taste receptor type 2 member 8 TAS2R8 Tbio GPCR -0.29740 1.91 25
Taste receptor type 2 member 7 TAS2R7 Tbio GPCR -0.48711 3.31 94