Development Level

Tbio 23 | 10,625
Tchem 10 | 1,890
Tdark 4 | 7,003
Tclin 3 | 602

Collection

GPCR: IDG Consortium (Targets) 23 | 128

IMPC Phenotype

cataract 1 | 26
hyperactivity 1 | 108
impaired pupillary reflex 1 | 14
increased circulating HDL chol... 1 | 63
increased circulating choleste... 1 | 53
increased heart weight 1 | 37
mydriasis 1 | 9

Disease

medulloblastoma, large-cell 13 | 6,234
psoriasis 11 | 6,685
Carcinoma 10 | 2,147
Schizophrenia 7 | 503
adult high grade glioma 7 | 2,148
Autistic Disorder 6 | 320
Epilepsy 6 | 346
atypical teratoid / rhabdoid tumor 6 | 4,369
glioblastoma 6 | 5,572
osteosarcoma 6 | 7,933
primitive neuroectodermal tumor 6 | 3,031
Epilepsy, Temporal Lobe 5 | 23
Pelvic inflammatory disease 5 | 21
lung cancer 5 | 4,473
oligodendroglioma 5 | 2,849
pilocytic astrocytoma 5 | 3,086
Alcohol dependence 4 | 107
Attention deficit hyperactivity disorder 4 | 156
Parkinson's disease 4 | 364
Toxic encephalopathy 4 | 131
diabetes mellitus 4 | 1,663
posterior fossa group A ependymoma 4 | 1,511
subependymal giant cell astrocytoma 4 | 2,287
Alcoholic Intoxication, Chronic 3 | 41
Major Depressive Disorder 3 | 106
Melanoma 3 | 261
Narcolepsy 3 | 69
Nicotine dependence 3 | 53
Pick disease 3 | 1,893
astrocytic glioma 3 | 2,241
ependymoma 3 | 2,514
lung carcinoma 3 | 2,844
ovarian cancer 3 | 8,491
pituitary cancer 3 | 1,972
sonic hedgehog group medulloblastoma 3 | 1,482
Acquired immunodeficiency syndrome 2 | 164
Bipolar Disorder 2 | 266
Breast cancer 2 | 3,098
Cataplexy and narcolepsy 2 | 3
Cocaine-Related Disorders 2 | 88
Fragile X syndrome 2 | 31
Muscle Spasticity of Cerebral Origin 2 | 8
Muscle spasticity of spinal origin 2 | 8
Status Epilepticus 2 | 85
Substance-Related Disorders 2 | 114
astrocytoma 2 | 1,493
medulloblastoma 2 | 1,524
pediatric high grade glioma 2 | 2,712
tuberculosis 2 | 1,563
Adenoma 1 | 165
Amyotrophic Lateral Sclerosis 1 | 432
Anxiety Disorders 1 | 37
Asthenopia 1 | 11
Basal ganglia calcification 1 | 17
Calcinosis 1 | 63
Cardiovascular system disease 1 | 194
Cerebellar Ataxia 1 | 72
Cocaine dependence 1 | 24
Common cold 1 | 63
Congenital stationary night blindness 1 | 28
Dental caries 1 | 67
Diabetic Neuropathies 1 | 13
Disease of metabolism 1 | 15
Disuse amblyopia 1 | 3
Enophthalmos 1 | 12
Fibroma 1 | 16
Gastroesophageal reflux disease 1 | 37
Gliosis 1 | 16
Hemochromatosis 1 | 55
Huntington's disease 1 | 72
Hyperactive behavior 1 | 31
Hypercalcemia 1 | 37
Hyperhomocysteinemia 1 | 34
Hyperparathyroidism 1 | 43
Hyperphosphatemia 1 | 32
Hypocalcemia, Autosomal Dominant 1 1 | 2
Hypoparathyroidism 1 | 29
Hypophosphatemia 1 | 31
Idiopathic generalized epilepsy 1 | 15
Interstitial nephritis 1 | 6
Mental depression 1 | 58
Multiple Endocrine Neoplasia Type 1 1 | 30
Myopia 1 | 99
Nerve Degeneration 1 | 73
Neuralgia 1 | 16
Neurodegenerative disease 1 | 383
Night Blindness 1 | 39
Osteoporosis 1 | 259
Panic disorder 1 | 55
Psychoses, Substance-Induced 1 | 17
Rectal neoplasm 1 | 7
Retinitis 1 | 9
Secondary hyperparathyroidism 1 | 6
Small cell carcinoma of lung 1 | 45
Stomatitis 1 | 19
Suppression amblyopia 1 | 6
adrenocortical adenoma 1 | 134
atypical teratoid/rhabdoid tumor 1 | 1,095
interstitial lung disease 1 | 292
substance-related disorder 1 | 104

Tissue

Female tissues 38 | 18,646
Nervous System 38 | 18,560
Urinary Tract 38 | 18,443
Digestive Tract 36 | 18,472
Endocrine System 36 | 18,511
Blood and immune system 33 | 17,994
Cardiovascular System 33 | 17,957
Skin and soft tissues 33 | 18,114
Liver and Pancreas 31 | 18,135
Male tissues 30 | 17,968
Respiratory system 29 | 17,483

Target Family

GPCR 39 | 408
Non-IDG 1 | 11,969

Reactome Pathway

Class C/3 (Metabotropic glutam... 40 | 40
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Metabotropic glutamate receptor 2 GRM2 Tchem GPCR -2.74553 574.9 269
Taste receptor type 2 member 45 TAS2R45 Tdark Non-IDG 0.00000 0
Taste receptor type 2 member 38 TAS2R38 Tbio GPCR -2.18733 151.7 62
Metabotropic glutamate receptor 6 GRM6 Tbio GPCR -1.97457 89.0 238
Taste receptor type 1 member 3 TAS1R3 Tbio GPCR -2.22623 165.4 232
Taste receptor type 1 member 1 TAS1R1 Tbio GPCR -1.74507 50.8 165
Metabotropic glutamate receptor 8 GRM8 Tchem GPCR -1.94182 88.2 272
Gamma-aminobutyric acid type B receptor subunit 2 GABBR2 Tclin GPCR -1.94197 83.3 313
Gamma-aminobutyric acid type B receptor subunit 1 GABBR1 Tclin GPCR -2.39487 246.1 321
G-protein coupled receptor family C group 6 member A GPRC6A Tbio GPCR -1.62030 46.6 158