Development Level

Tbio 27 | 11,651
Tchem 6 | 1,388
Tdark 4 | 6,593
Tclin 2 | 612

Collection

GPCR: IDG Consortium (Targets) 23 | 126

IMPC Phenotype

increased circulating triglyce... 2 | 42
abnormal eye morphology 1 | 68
abnormal heart morphology 1 | 162
cataract 1 | 92
decreased vertical activity 1 | 208
enlarged heart 1 | 210
hyperactivity 1 | 148
impaired pupillary reflex 1 | 26
increased circulating choleste... 1 | 66
increased heart weight 1 | 62
increased hemoglobin content 1 | 45
increased kidney weight 1 | 6
increased mean platelet volume 1 | 45
limb grasping 1 | 41
microphthalmia 1 | 26
mydriasis 1 | 6

Disease

Carcinoma 27 | 11,493
medulloblastoma, large-cell 13 | 6,241
psoriasis 10 | 6,694
Alcoholic Intoxication, Chronic 9 | 289
Kidney cancer 9 | 2,613
Schizophrenia 8 | 1,160
adult high grade glioma 8 | 3,801
lung cancer 8 | 4,740
atypical teratoid / rhabdoid tumor 7 | 5,112
ependymoma 7 | 4,679
glioblastoma 7 | 5,792
Autistic Disorder 6 | 364
group 3 medulloblastoma 6 | 4,104
primitive neuroectodermal tumor 6 | 3,035
Astrocytoma, Pilocytic 5 | 3,081
Epilepsy 5 | 792
Epilepsy, Temporal Lobe 5 | 23
Melanoma 5 | 711
Pelvic inflammatory disease 5 | 21
diabetes mellitus 5 | 1,728
oligodendroglioma 5 | 2,850
osteosarcoma 5 | 7,950
Alcohol dependence 4 | 107
Attention Deficit Disorder with Hyperactivity 4 | 21
Attention deficit hyperactivity disorder 4 | 278
Bipolar Disorder 4 | 666
Liver cancer 4 | 604
Major Depressive Disorder 4 | 301
Parkinson's disease 4 | 392
Toxic encephalopathy 4 | 141
Unipolar Depression 4 | 250
astrocytic glioma 4 | 2,597
subependymal giant cell astrocytoma 4 | 2,287
Alcoholism 3 | 45
Breast cancer 3 | 3,578
Common cold 3 | 69
Mental Depression 3 | 333
Narcolepsy 3 | 72
Nicotine dependence 3 | 54
Pick disease 3 | 1,894
Skin cancer 3 | 469
ovarian cancer 3 | 8,520
pituitary cancer 3 | 1,972
Acquired immunodeficiency syndrome 2 | 197
Autosomal recessive predisposition 2 | 1,442
Cataplexy and narcolepsy 2 | 3
Cocaine-Related Disorders 2 | 92
Dental caries 2 | 164
Depressive disorder 2 | 409
Fragile X syndrome 2 | 34
Intellectual disability 2 | 1,016
Mood Disorders 2 | 184
Muscle Spasticity of Cerebral Origin 2 | 8
Muscle spasticity of spinal origin 2 | 8
Obesity 2 | 678
Status Epilepticus 2 | 98
Substance-Related Disorders 2 | 115
Suppression amblyopia 2 | 8
addicted to cocaine 2 | 4
lung carcinoma 2 | 2,843
tuberculosis 2 | 2,010
Acquired metabolic disease 1 | 336
Anxiety Disorders 1 | 38
Atrophy of cerebellum 1 | 103
Autosomal recessive congenital ichthyosis 11 1 | 10
Blepharoptosis 1 | 231
Brain Injuries 1 | 65
Cerebellar degeneration 1 | 103
Cocaine Dependence 1 | 51
Congenital stationary night blindness 1 | 29
DOID:2627 1 | 94
Difficulties with night vision 1 | 87
Dilated ventricles (finding) 1 | 121
Disease of metabolism 1 | 18
Dysarthria 1 | 192
Enophthalmos 1 | 75
Esotropia 1 | 31
Gastroesophageal reflux disease 1 | 110
Hemeralopia 1 | 4
Hyperactive behavior 1 | 91
Hyperkinesis 1 | 32
Hypotrichosis 1 1 | 15
Infantile onset 1 | 238
Infratentorial atrophy 1 | 103
Myocardial Infarction 1 | 151
Myopia 1 | 176
Nerve Degeneration 1 | 121
Neuralgia 1 | 20
Night Blindness 1 | 101
Night blindness, congenital stationary 1 | 16
Pain agnosia 1 | 104
Panic disorder 1 | 61
Rectal neoplasm 1 | 6
Retinal Degeneration 1 | 106
Retinitis pigmentosa 10 1 | 6
Slow progression 1 | 89
Spinocerebellar Ataxias 1 | 34
Tremor 1 | 113
interstitial lung disease 1 | 298
obsessive-compulsive disorder 1 | 61

Tissue

Endocrine System 25 | 18,159
Female tissues 24 | 17,400
Blood and immune system 20 | 16,909
Male tissues 19 | 17,142
Nervous System 19 | 16,725
Digestive Tract 18 | 17,369
Skin and soft tissues 18 | 17,230
Liver and Pancreas 15 | 16,750
Urinary Tract 15 | 16,678
Respiratory system 14 | 16,393
Cardiovascular System 6 | 15,192

Target Family

GPCR 38 | 408
Non-IDG 1 | 12,091

Reactome Pathway

Class C/3 (Metabotropic glutam... 39 | 39
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Metabotropic glutamate receptor 2 GRM2 Tchem GPCR -2.77035 612.3 315
Taste receptor type 2 member 8 TAS2R8 Tbio GPCR -0.53821 3.18 29
Taste receptor type 2 member 7 TAS2R7 Tbio GPCR -0.64156 4.31 106
Taste receptor type 1 member 3 TAS1R3 Tbio GPCR -2.25430 179.4 244
Taste receptor type 2 member 41 TAS2R41 Tbio GPCR 0.40 1.00 69
Taste receptor type 2 member 38 TAS2R38 Tbio GPCR -2.22573 165.0 81
Metabotropic glutamate receptor 6 GRM6 Tbio GPCR -1.98705 92.3 263
Taste receptor type 2 member 45 TAS2R45 Tdark Non-IDG 0.00000 0
Taste receptor type 2 member 31 TAS2R31 Tbio GPCR -0.87986 6.94 69
Taste receptor type 2 member 46 TAS2R46 Tbio GPCR -0.87469 6.92 9