Development Level

Tbio 7 | 11,445
Tchem 2 | 1,598

IMPC Phenotype

abnormal tooth morphology 1 | 24
decreased circulating glucose ... 1 | 126
decreased circulating serum al... 1 | 82
decreased circulating sodium l... 1 | 22
decreased erythrocyte cell num... 1 | 62
increased circulating LDL chol... 1 | 13
increased circulating alkaline... 1 | 122
increased circulating bilirubi... 1 | 16
increased circulating choleste... 1 | 66
increased circulating free fat... 1 | 20
increased circulating triglyce... 1 | 42
increased mean corpuscular hem... 1 | 36
increased total body fat amoun... 1 | 134

Disease

Atherosclerosis 8 | 291
Coronary artery disease 8 | 268
Lipid metabolism disorder 7 | 114
Hypercholesterolemia, Familial 6 | 23
Hyperlipoproteinemia Type II 6 | 12
Obesity 6 | 678
diabetes mellitus 6 | 1,728
psoriasis 6 | 6,694
Cardiovascular system disease 5 | 246
osteosarcoma 5 | 7,950
Autosomal recessive predisposition 4 | 1,442
Cardiovascular Diseases 4 | 59
Familial hyperlipidemia 4 | 6
Hypercholesterolemia 4 | 44
Hypercholesterolemia, Autosomal Dominant, Type B 4 | 5
Hyperlipidemia 4 | 43
Hypertension 4 | 396
Kidney disease 4 | 430
Pancreatitis 4 | 123
Serum cholesterol raised 4 | 22
invasive ductal carcinoma 4 | 2,951
pancreatic ductal adenocarcinoma liver metastasis 4 | 1,962
Arcus Senilis 3 | 11
Breast cancer 3 | 3,578
Carcinoma 3 | 11,493
Dyslipidemias 3 | 27
Hyperglycemia 3 | 137
Hyperlipidemias 3 | 17
Hyperlipoproteinemia Type IIa 3 | 11
Hypertensive disease 3 | 292
Hypertriglyceridemia 3 | 17
Myocardial Infarction 3 | 151
Schizophrenia 3 | 1,160
Splenomegaly 3 | 190
Vascular disease 3 | 319
ductal carcinoma in situ 3 | 1,745
Amyloidosis 2 | 67
Arcus juvenilis 2 | 5
Atopic dermatitis 2 | 952
Cancer 2 | 2,499
Cerebrovascular disease 2 | 238
Coronary Disease 2 | 25
Coronary heart disease 2 | 16
Drug Eruptions 2 | 18
Eruptive xanthoma 2 | 3
Eyelid Xanthoma 2 | 5
Fatty liver disease 2 | 103
Heart disease 2 | 306
Hepatomegaly 2 | 285
Hyperinsulinism 2 | 133
Hyperlipoproteinemia Type I 2 | 2
Hyperlipoproteinemia Type V 2 | 3
Hyperlipoproteinemia type III 2 | 4
Hypertriglyceridemia result 2 | 37
Hypobetalipoproteinemias 2 | 5
Kidney Failure 2 | 111
Lipidemia retinalis 2 | 4
Liver Cirrhosis, Experimental 2 | 769
Liver Neoplasms, Experimental 2 | 59
Liver disease 2 | 237
Low density lipoprotein decreased 2 | 5
Low density lipoprotein increased 2 | 8
Lung Neoplasms 2 | 232
Metabolic syndrome X 2 | 52
Steatohepatitis 2 | 44
Type 2 diabetes mellitus 2 | 272
Xanthelasma of periocular region 2 | 5
Xanthoma 2 | 5
Xanthoma of periocular region 2 | 5
Xanthomatosis 2 | 12
adult high grade glioma 2 | 3,801
breast carcinoma 2 | 1,638
fibroadenoma 2 | 559
glioblastoma 2 | 5,792
intraductal papillary-mucinous neoplasm (IPMN) 2 | 3,291
lung adenocarcinoma 2 | 2,716
malignant mesothelioma 2 | 3,232
nasopharyngeal carcinoma 2 | 1,058
non-small cell lung cancer 2 | 2,890
oligodendroglioma 2 | 2,850
ovarian cancer 2 | 8,520
Abetalipoproteinemia 1 | 7
Carotid Artery Diseases 1 | 11
Carotid stenosis 1 | 5
Delirium 1 | 10
Edema 1 | 81
Emphysema 1 | 12
Hepatolenticular Degeneration 1 | 24
Hepatosplenomegaly 1 | 22
Hypotriglyceridaemia 1 | 3
Impaired left ventricular function 1 | 16
Left-Sided Heart Failure 1 | 16
Long tract signs 1 | 3
Macular Degeneration, Age-Related, 1 1 | 9
Nausea 1 | 20
Neurofibrillary degeneration (morphologic abnormality) 1 | 9
Pathological accumulation of air in tissues 1 | 10
Plaque build-up in arteries supplying blood to heart 1 | 6
Renal Artery Stenosis 1 | 9
Renal glomerular disease 1 | 12

Tissue

Digestive Tract 9 | 17,369
Endocrine System 9 | 18,159
Female tissues 9 | 17,400
Liver and Pancreas 9 | 16,750
Skin and soft tissues 9 | 17,230
Blood and immune system 8 | 16,909
Male tissues 8 | 17,142
Urinary Tract 8 | 16,678
Respiratory system 6 | 16,393
Cardiovascular System 5 | 15,192
Nervous System 5 | 16,725

Target Family

Non-IDG 8 | 12,091
Enzyme 1 | 4,145

Reactome Pathway

Chylomicron remodeling 9 | 9
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 GPIHBP1 Tbio Non-IDG -1.82315 79.6 104
Apolipoprotein A-V APOA5 Tbio Non-IDG -2.58826 425.0 481
Lipoprotein lipase LPL Tchem Enzyme -3.09646 876.3 338
Apolipoprotein B-100 APOB Tchem Non-IDG -4.00022 10024.1 856
Apolipoprotein C-III APOC3 Tbio Non-IDG -2.93348 875.2 267
Apolipoprotein C-II APOC2 Tbio Non-IDG -2.51086 342.7 22
Apolipoprotein A-II APOA2 Tbio Non-IDG -2.81123 595.2 420
Apolipoprotein E APOE Tbio Non-IDG -4.20176 15904.9 976
Apolipoprotein A-IV APOA4 Tbio Non-IDG -2.45218 211.8 324