Development Level

Tbio 31 | 11,651
Tchem 13 | 1,388
Tclin 3 | 612

IMPC Phenotype

decreased vertical activity 2 | 208
decreased circulating insulin ... 1 | 76
decreased fasted circulating g... 1 | 65
decreased heart rate 1 | 18
decreased neutrophil cell numb... 1 | 42
embryonic lethality prior to o... 1 | 239
embryonic lethality prior to t... 1 | 278
enlarged uterus 1 | 11
hydrometra 1 | 53
hyperactivity 1 | 148
improved glucose tolerance 1 | 79
increased circulating HDL chol... 1 | 80
increased circulating calcium ... 1 | 34
increased circulating creatini... 1 | 38
increased circulating magnesiu... 1 | 10
increased circulating total pr... 1 | 28
preweaning lethality, complete... 1 | 979
prolonged RR interval 1 | 8
small superior vagus ganglion 1 | 74

Disease

psoriasis 30 | 6,694
Cancer 29 | 2,499
interstitial cystitis 26 | 2,312
lung cancer 22 | 4,740
lung carcinoma 21 | 2,843
ovarian cancer 21 | 8,520
tuberculosis 21 | 2,010
Multiple Sclerosis 18 | 540
malignant mesothelioma 18 | 3,232
Rheumatoid arthritis 17 | 1,191
cutaneous lupus erythematosus 17 | 1,057
lung adenocarcinoma 17 | 2,716
osteosarcoma 16 | 7,950
ulcerative colitis 16 | 1,819
Carcinoma 15 | 11,493
Hypersensitivity reaction type II disease 15 | 253
adult high grade glioma 15 | 3,801
non-small cell lung cancer 15 | 2,890
Asthma 14 | 385
Hypersensitivity 14 | 63
cystic fibrosis 14 | 1,696
glioblastoma 14 | 5,792
invasive ductal carcinoma 14 | 2,951
Breast cancer 13 | 3,578
Pneumonia 13 | 174
breast carcinoma 13 | 1,638
pancreatic cancer 13 | 2,398
Arthritis 12 | 290
Lung disease 11 | 142
medulloblastoma, large-cell 11 | 6,241
primary Sjogren syndrome 11 | 735
Atherosclerosis 10 | 291
Dermatitis 10 | 157
Human immunodeficiency virus infectious disease 10 | 138
Inflammatory bowel disease 10 | 151
colon cancer 10 | 1,478
intraductal papillary-mucinous adenoma (IPMA) 10 | 2,955
intraductal papillary-mucinous carcinoma (IPMC) 10 | 2,989
sarcoidosis 10 | 370
active Crohn's disease 9 | 922
active ulcerative colitis 9 | 764
atypical teratoid / rhabdoid tumor 9 | 5,112
ductal carcinoma in situ 9 | 1,745
ependymoma 9 | 4,679
hepatocellular carcinoma 9 | 547
mucosa-associated lymphoid tissue lymphoma 9 | 484
Kidney disease 8 | 430
head and neck cancer 8 | 271
Astrocytoma, Pilocytic 7 | 3,081
Breast Neoplasms 7 | 445
Coronary artery disease 7 | 268
Liver Cirrhosis, Experimental 7 | 769
Mammary Neoplasms 7 | 425
Pulmonary Fibrosis 7 | 106
diabetes mellitus 7 | 1,728
esophageal adenocarcinoma 7 | 737
head and neck cancer and chronic obstructive pulmonary disease 7 | 239
juvenile dermatomyositis 7 | 1,187
nasopharyngeal carcinoma 7 | 1,058
periodontitis 7 | 293
Acquired immunodeficiency syndrome 6 | 197
Arthritis, Rheumatoid 6 | 174
Influenza 6 | 142
Malaria 6 | 160
Mesothelioma, Malignant 6 | 105
Status Epilepticus 6 | 98
gastric cancer 6 | 459
gastric carcinoma 6 | 807
intraductal papillary-mucinous neoplasm (IPMN) 6 | 3,291
non primary Sjogren syndrome sicca 6 | 891
pancreatic carcinoma 6 | 562
Atopic dermatitis 5 | 952
Barrett's esophagus 5 | 182
Cerebrovascular disease 5 | 238
Colitis, Ulcerative 5 | 59
Dermatitis, Atopic 5 | 37
Encephalitis 5 | 64
Hepatitis C 5 | 94
Hypertension 5 | 396
Vascular disease 5 | 319
posterior fossa group A ependymoma 5 | 468
Arsenic Poisoning 4 | 62
Biliary cirrhosis 4 | 45
Celiac disease 4 | 116
Dermatologic disorders 4 | 93
Eye disease 4 | 62
Glomerulonephritis 4 | 46
HIV Infections 4 | 102
Liver Cirrhosis, Biliary 4 | 33
Liver disease 4 | 237
Mastitis 4 | 48
Obesity 4 | 678
Osteoarthritis 4 | 184
Skin Diseases 4 | 71
chronic rhinosinusitis 4 | 512
nephrosclerosis 4 | 333
non-small cell lung carcinoma 4 | 317
subependymal giant cell astrocytoma 4 | 2,287
urothelial carcinoma 4 | 318
Pick disease 3 | 1,894

Tissue

Blood and immune system 47 | 16,909
Digestive Tract 47 | 17,369
Endocrine System 47 | 18,159
Female tissues 47 | 17,400
Liver and Pancreas 47 | 16,750
Male tissues 47 | 17,142
Respiratory system 46 | 16,393
Skin and soft tissues 46 | 17,230
Urinary Tract 46 | 16,678
Nervous System 45 | 16,725
Cardiovascular System 37 | 15,192

Target Family

Non-IDG 27 | 12,091
GPCR 20 | 408

Reactome Pathway

Chemokine receptors bind chemo... 47 | 47
Signal Transduction 2,657 | 2,657
Immune System 2,101 | 2,101
Metabolism of proteins 2,091 | 2,091
Metabolism 2,081 | 2,081
Post-translational protein mod... 1,398 | 1,398
Gene expression (Transcription... 1,369 | 1,369
RNA Polymerase II Transcriptio... 1,228 | 1,228
Signaling by GPCR 1,217 | 1,217
Innate Immune System 1,176 | 1,176
GPCR downstream signalling 1,157 | 1,157
Generic Transcription Pathway 1,108 | 1,108
Developmental Biology 1,026 | 1,026
Adaptive Immune System 892 | 892
Disease 879 | 879
Cytokine Signaling in Immune s... 752 | 752
Metabolism of lipids 739 | 739
Vesicle-mediated transport 720 | 720
Transport of small molecules 717 | 717
Metabolism of RNA 682 | 682
Hemostasis 666 | 666
Membrane Trafficking 608 | 608
Cell Cycle 590 | 590
G alpha (s) signalling events 574 | 574
Neutrophil degranulation 539 | 539
Axon guidance 533 | 533
Cell Cycle, Mitotic 488 | 488
Cellular responses to external... 463 | 463
GPCR ligand binding 459 | 459
Signaling by Interleukins 448 | 448
Class I MHC mediated antigen p... 435 | 435
Signaling by Receptor Tyrosine... 430 | 430
Olfactory Signaling Pathway 428 | 428
Infectious disease 404 | 404
G alpha (i) signalling events 394 | 394
Cellular responses to stress 386 | 386
Signaling by Rho GTPases 386 | 386
Metabolism of amino acids and ... 370 | 370
Diseases of signal transductio... 367 | 367
Neuronal System 367 | 367
Transcriptional Regulation by ... 365 | 365
M Phase 344 | 344
Class A/1 (Rhodopsin-like rece... 322 | 322
Antigen processing: Ubiquitina... 306 | 306
Extracellular matrix organizat... 297 | 297
Translation 297 | 297
Signaling by WNT 293 | 293
Intracellular signaling by sec... 289 | 289
DNA Repair 288 | 288
Asparagine N-linked glycosylat... 287 | 287
MAPK family signaling cascades 285 | 285
Deubiquitination 276 | 276
Interferon Signaling 275 | 275
Immunoregulatory interactions ... 272 | 272
Metabolism of carbohydrates 271 | 271
Cell Cycle Checkpoints 270 | 270
Organelle biogenesis and maint... 261 | 261
PIP3 activates AKT signaling 259 | 259
RHO GTPase Effectors 257 | 257
Platelet activation, signaling... 256 | 256
HIV Infection 254 | 254
MAPK1/MAPK3 signaling 244 | 244
SLC-mediated transmembrane tra... 243 | 243
Processing of Capped Intron-Co... 238 | 238
RAF/MAP kinase cascade 238 | 238
Chromatin modifying enzymes 236 | 236
Chromatin organization 236 | 236
Neddylation 234 | 234
Transmission across Chemical S... 221 | 221
Biological oxidations 220 | 220
Signaling by ROBO receptors 219 | 219
Keratinization 216 | 216
rRNA processing 216 | 216
G alpha (q) signalling events 211 | 211
Cell surface interactions at t... 210 | 210
Phospholipid metabolism 209 | 209
Fc epsilon receptor (FCERI) si... 204 | 204
Transcriptional regulation by ... 203 | 203
Ub-specific processing proteas... 203 | 203
TCF dependent signaling in res... 199 | 199
Muscle contraction 198 | 198
rRNA processing in the nucleus... 192 | 192
Metabolism of vitamins and cof... 188 | 188
Peptide ligand-binding recepto... 188 | 188
mRNA Splicing 187 | 187
Cilium Assembly 186 | 186
Intra-Golgi and retrograde Gol... 186 | 186
Mitotic G2-G2/M phases 184 | 184
Mitotic Metaphase and Anaphase 183 | 183
G2/M Transition 182 | 182
Major pathway of rRNA processi... 182 | 182
Mitotic Anaphase 182 | 182
Mitotic Prometaphase 181 | 181
Fatty acid metabolism 180 | 180
mRNA Splicing - Major Pathway 179 | 179
Ion channel transport 177 | 177
Signaling by the B Cell Recept... 176 | 176
Regulation of expression of SL... 173 | 173
Programmed Cell Death 172 | 172
Interferon gamma signaling 171 | 171
Separation of Sister Chromatid... 170 | 170

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-C motif chemokine 27 CCL27 Tbio Non-IDG -2.72180 519.6 214
C-X-C motif chemokine 5 CXCL5 Tbio Non-IDG -2.44551 266.4 370
C-C chemokine receptor type 2 CCR2 Tchem GPCR -3.06548 1112.4 530
C-C motif chemokine 19 CCL19 Tbio Non-IDG -2.45693 253.7 310
C-X-C motif chemokine 10 CXCL10 Tbio Non-IDG -3.27118 1942.1 623
Platelet factor 4 PF4 Tbio Non-IDG -3.30967 2121.0 327
C-X-C chemokine receptor type 4 CXCR4 Tclin GPCR -3.41606 2525.3 1240
C-X-C motif chemokine 13 CXCL13 Tbio Non-IDG -2.76402 588.7 429
C-C motif chemokine 25 CCL25 Tbio Non-IDG -1.79784 59.1 303
C-X-C motif chemokine 9 CXCL9 Tbio Non-IDG -2.97954 923.8 413