Development Level

Tbio 26 | 10,625
Tchem 19 | 1,890
Tclin 3 | 602

IMPC Phenotype

decreased NK T cell number 2 | 28
increased circulating total pr... 2 | 20
preweaning lethality, complete... 2 | 633
decreased CD8-positive, alpha-... 1 | 26
decreased alpha-beta T cell nu... 1 | 12
decreased circulating glucose ... 1 | 121
decreased circulating insulin ... 1 | 75
decreased circulating thyroxin... 1 | 5
decreased dendritic cell numbe... 1 | 3
decreased fasted circulating g... 1 | 49
decreased grip strength 1 | 123
decreased lumbar vertebrae num... 1 | 62
improved glucose tolerance 1 | 56
increased KLRG1-positive gamma... 1 | 2
increased circulating HDL chol... 1 | 63
increased circulating calcium ... 1 | 32
increased circulating creatini... 1 | 29
increased effector memory CD8-... 1 | 14
increased effector memory T-he... 1 | 5
increased gamma-delta T cell n... 1 | 16
increased monocyte cell number 1 | 27
increased myeloid cell number 1 | 2
increased sacral vertebrae num... 1 | 62
increased thoracic vertebrae n... 1 | 8

Disease

psoriasis 31 | 6,685
Cancer 28 | 2,346
interstitial cystitis 26 | 2,299
lung cancer 23 | 4,473
ulcerative colitis 23 | 2,087
ovarian cancer 22 | 8,491
lung carcinoma 21 | 2,844
tuberculosis 20 | 1,563
lung adenocarcinoma 18 | 2,714
Multiple Sclerosis 17 | 498
cutaneous lupus erythematosus 17 | 1,056
Rheumatoid Arthritis 16 | 1,170
osteosarcoma 16 | 7,933
Hypersensitivity reaction type II disease 15 | 235
invasive ductal carcinoma 15 | 2,950
malignant mesothelioma 15 | 3,163
non-small cell lung cancer 15 | 2,798
Asthma 14 | 349
breast carcinoma 14 | 1,614
cystic fibrosis 14 | 1,670
glioblastoma 14 | 5,572
primary Sjogren syndrome 14 | 788
Hypersensitivity 13 | 63
Pneumonia 13 | 133
adult high grade glioma 13 | 2,148
pancreatic cancer 13 | 2,300
posterior fossa group A ependymoma 13 | 1,511
Breast cancer 12 | 3,098
Arthritis 11 | 248
Lung disease 11 | 136
intraductal papillary-mucinous adenoma (IPMA) 11 | 2,956
intraductal papillary-mucinous carcinoma (IPMC) 11 | 2,988
medulloblastoma, large-cell 11 | 6,234
Atherosclerosis 10 | 275
Inflammatory bowel disease 10 | 142
atypical teratoid / rhabdoid tumor 10 | 4,369
colon cancer 10 | 1,475
ductal carcinoma in situ 10 | 1,745
hepatocellular carcinoma 10 | 550
sarcoidosis 10 | 368
Dermatitis 9 | 141
Human immunodeficiency virus infectious disease 9 | 129
active Crohn's disease 9 | 918
mucosa-associated lymphoid tissue lymphoma 9 | 480
Kidney disease 8 | 397
gastric carcinoma 8 | 832
head and neck cancer 8 | 270
Coronary artery disease 7 | 240
esophageal adenocarcinoma 7 | 737
intraductal papillary-mucinous neoplasm (IPMN) 7 | 3,289
juvenile dermatomyositis 7 | 1,189
nasopharyngeal carcinoma 7 | 1,056
periodontitis 7 | 269
pilocytic astrocytoma 7 | 3,086
Atopic dermatitis 6 | 944
Influenza 6 | 142
Mammary Neoplasms 6 | 410
Status Epilepticus 6 | 85
Vascular disease 6 | 281
diabetes mellitus 6 | 1,663
head and neck cancer and chronic obstructive pulmonary disease 6 | 237
pancreatic carcinoma 6 | 567
Acquired immunodeficiency syndrome 5 | 164
Barrett's esophagus 5 | 185
Cerebrovascular disease 5 | 231
Dermatitis, Atopic 5 | 45
Pulmonary Fibrosis 5 | 66
chronic rhinosinusitis 5 | 512
gastric cancer 5 | 436
Arsenic Poisoning 4 | 59
Biliary cirrhosis 4 | 33
Celiac disease 4 | 112
Dermatologic disorders 4 | 65
Encephalitis 4 | 54
Eye disease 4 | 55
Glomerulonephritis 4 | 36
HIV Infections 4 | 99
Hepatitis C 4 | 90
Malaria 4 | 140
Mastitis 4 | 48
Obesity 4 | 616
adrenocortical carcinoma 4 | 1,427
nephrosclerosis 4 | 329
non-small cell lung carcinoma 4 | 413
pediatric high grade glioma 4 | 2,712
pituitary cancer 4 | 1,972
subependymal giant cell astrocytoma 4 | 2,287
urothelial carcinoma 4 | 318
Contact Dermatitis 3 | 80
Endometriosis 3 | 535
Myocardial Ischemia 3 | 169
Pick disease 3 | 1,893
Prostatic Neoplasms 3 | 471
Waldenstrons macroglobulinemia 3 | 764
acute myeloid leukemia 3 | 785
aldosterone-producing adenoma 3 | 664
dermatomyositis 3 | 966
pancreatic ductal adenocarcinoma liver metastasis 3 | 1,795
primary pancreatic ductal adenocarcinoma 3 | 1,271
sonic hedgehog group medulloblastoma 3 | 1,482

Tissue

Blood and immune system 48 | 17,994
Digestive Tract 47 | 18,472
Female tissues 47 | 18,646
Respiratory system 47 | 17,483
Endocrine System 46 | 18,511
Liver and Pancreas 46 | 18,135
Nervous System 46 | 18,560
Skin and soft tissues 46 | 18,114
Urinary Tract 46 | 18,443
Cardiovascular System 45 | 17,957
Male tissues 45 | 17,968

Target Family

Non-IDG 27 | 11,969
GPCR 21 | 408

Reactome Pathway

Chemokine receptors bind chemo... 48 | 48
Signal Transduction 2,515 | 2,515
Immune System 2,183 | 2,183
Metabolism 2,131 | 2,131
Gene Expression 1,754 | 1,754
Metabolism of proteins 1,544 | 1,544
Innate Immune System 1,375 | 1,375
Signaling by GPCR 1,329 | 1,329
Developmental Biology 1,028 | 1,028
GPCR downstream signaling 1,015 | 1,015
Post-translational protein mod... 1,004 | 1,004
Adaptive Immune System 938 | 938
Disease 855 | 855
Generic Transcription Pathway 852 | 852
Cytokine Signaling in Immune s... 803 | 803
Metabolism of lipids and lipop... 797 | 797
Vesicle-mediated transport 705 | 705
Hemostasis 669 | 669
Transmembrane transport of sma... 668 | 668
Membrane Trafficking 608 | 608
Cell Cycle 572 | 572
Neutrophil degranulation 542 | 542
Axon guidance 541 | 541
Signaling by Interleukins 500 | 500
Cell Cycle, Mitotic 470 | 470
Signalling by NGF 467 | 467
GPCR ligand binding 456 | 456
Gastrin-CREB signalling pathwa... 435 | 435
Class I MHC mediated antigen p... 430 | 430
Olfactory Signaling Pathway 430 | 430
Fc epsilon receptor (FCERI) si... 423 | 423
Cellular responses to stress 415 | 415
DAP12 interactions 409 | 409
Infectious disease 391 | 391
NGF signalling via TRKA from t... 378 | 378
Signaling by Rho GTPases 378 | 378
Signaling by PDGF 367 | 367
Diseases of signal transductio... 359 | 359
Transcriptional Regulation by ... 356 | 356
Signaling by EGFR 355 | 355
Metabolism of amino acids and ... 353 | 353
DAP12 signaling 346 | 346
Downstream signal transduction 343 | 343
Neuronal System 343 | 343
Organelle biogenesis and maint... 334 | 334
Signaling by VEGF 329 | 329
Signaling by SCF-KIT 327 | 327
Class A/1 (Rhodopsin-like rece... 322 | 322
VEGFA-VEGFR2 Pathway 321 | 321
FCERI mediated MAPK activation 316 | 316
Signaling by Insulin receptor 312 | 312
Antigen processing: Ubiquitina... 301 | 301
Extracellular matrix organizat... 292 | 292
Signaling by Type 1 Insulin-li... 290 | 290
Signaling by Wnt 290 | 290
IGF1R signaling cascade 289 | 289
IRS-related events triggered b... 289 | 289
Insulin receptor signalling ca... 288 | 288
Metabolism of carbohydrates 288 | 288
DNA Repair 286 | 286
IRS-mediated signalling 285 | 285
MAPK family signaling cascades 283 | 283
Asparagine N-linked glycosylat... 282 | 282
Signaling by the B Cell Recept... 282 | 282
SLC-mediated transmembrane tra... 280 | 280
Deubiquitination 277 | 277
Interferon Signaling 275 | 275
Platelet activation, signaling... 274 | 274
NCAM signaling for neurite out... 268 | 268
M Phase 266 | 266
Interleukin-3, 5 and GM-CSF si... 262 | 262
RET signaling 261 | 261
Signalling to ERKs 254 | 254
Interleukin-2 signaling 253 | 253
Immunoregulatory interactions ... 252 | 252
RHO GTPase Effectors 249 | 249
VEGFR2 mediated cell prolifera... 249 | 249
Signalling to RAS 247 | 247
Interleukin receptor SHC signa... 246 | 246
G alpha (i) signalling events 245 | 245
Fatty acid, triacylglycerol, a... 244 | 244
Signaling by Leptin 244 | 244
Prolonged ERK activation event... 243 | 243
MAPK1/MAPK3 signaling 242 | 242
Frs2-mediated activation 241 | 241
HIV Infection 241 | 241
ARMS-mediated activation 240 | 240
Signalling to p38 via RIT and ... 240 | 240
Chromatin modifying enzymes 237 | 237
Chromatin organization 237 | 237
GRB2 events in EGFR signaling 236 | 236
RAF/MAP kinase cascade 236 | 236
SHC1 events in EGFR signaling 236 | 236
SOS-mediated signalling 236 | 236
Processing of Capped Intron-Co... 235 | 235
Biological oxidations 215 | 215
Keratinization 213 | 213
Transmission across Chemical S... 210 | 210
rRNA processing 209 | 209
Ion channel transport 204 | 204
Phospholipid metabolism 202 | 202

This is where graphics are reside..
Name Gene Development Level Target Family Log Novelty  Pubmed Score  Antibody Count  Knowledge Availability 
C-X-C chemokine receptor type 1 CXCR1 Tchem GPCR -2.45436 257.8 324
Atypical chemokine receptor 3 ACKR3 Tchem GPCR -1.80879 81.4 385
C-C motif chemokine 28 CCL28 Tbio Non-IDG -2.19589 130.9 158
C-X-C motif chemokine 2 CXCL2 Tchem Non-IDG -2.41448 214.2 170
C-X-C motif chemokine 3 CXCL3 Tbio Non-IDG -1.92093 74.7 158
C-X-C motif chemokine 11 CXCL11 Tbio Non-IDG -2.70030 491.1 279
Growth-regulated alpha protein CXCL1 Tbio Non-IDG -3.10318 1174.2 351
C-X-C motif chemokine 16 CXCL16 Tbio Non-IDG -2.11956 154.1 229
Interleukin-8 CXCL8 Tchem Non-IDG -3.98343 9346.7 993
C-C motif chemokine 1 CCL1 Tbio Non-IDG -2.44724 261.3 157